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3D printing constitutes a technological advancement, revolutionizing contemporary industry by enabling manufacturers to fabricate intricate, customized components efficiently and precisely from digital blueprints. Moreover, the fusion of 3D printing with cutting‐edge materials has given rise to compelling elements boasting a diverse range of applications. For this reason, this work describes the incorporation of a luminescent material, NaYF4, doped with Yb3+ and Er3+, embedded in resin for 3D printing to create motorized luminescent gears. The fabricated luminescent gears take advantage of the intensity ratio between the Er3+ emissions at 525 nm (2H11/2 → 4I15/2) and 550 nm (4S3/2 → 4I15/2), which are thermally coupled, to detect the slight temperature variations that gears undergo through friction. This technique can be complementary to thermovision, proving especially valuable for monitoring temperature in elements where measurement with thermographic cameras or direct contact thermometers is hampered. The findings demonstrate that optical measurements provide enhanced (statistical) precision in temperature readings compared to thermovision, with δT = 0.07 K for luminescence thermometry as opposed to δT = 0.3 K for the thermal camera. This work can inspire new research directions using 3D printing and materials with exciting properties, fostering innovative solutions in contemporary industrial technologies. [ABSTRACT FROM AUTHOR]

Background: There is growing evidence regarding the prognostic utility of ratios such as neutrophil‐to‐lymphocyte ratio (NLR), platelet‐to‐lymphocyte ratio (PLR), and systemic immune‐inflammatory index (SIII) in head and neck squamous cell carcinoma (HNSCC). However, most studies to date include heterogeneous series with different treatments or tumor subsites. Methods: We collected data from 201 patients with stage I–II glottic squamous cell carcinoma treated with transoral laser surgery. NLR, PLR, and SIII were calculated from preoperative cell blood count, cut‐off points were obtained by ROC curve analysis, and survival rates were calculated. Results: High NLR (p = 0.012) and SIII (p = 0.037), but not PLR (p = 0.48), were associated with worse disease‐specific survival (DSS). A similar trend was observed with overall survival (OS), although it did not reach statistical significance. On multivariable analyses, both high NLR (HR = 3.8, 95% CI = 1.5–9.9, p = 0.006) and high SIII (HR = 2.77, 95% CI = 1.1–6.9, p = 0.03) were significantly associated with shortened DSS. Conclusions: Preoperative NLR and SIII emerge as independent prognostic biomarkers for early‐stage surgically treated glottic tumors and could guide individualized follow‐up. [ABSTRACT FROM AUTHOR]

Low‐valent cobalt complexes equipped with phosphorous type of ligands can promote the intramolecular (3+2) cycloaddition of alkylidenecyclopropanes (ACPs) with alkenes and with allenes. Dienes can also be used as partners, but they afford seven‐membered cycloadducts. The reactions are fully diastereoselective and, in some cases, we also observed moderate enantioselectivities, especially when using chiral phosphite ligands. [ABSTRACT FROM AUTHOR]

Nonlinear optical materials are essential in areas such as nanophotonics, optical information processing, and biomedical imaging. However, nanomaterials employed for these diverse applications to date are efficient only for one type of nonlinear optical activity. Herein, the first multimodal nonlinear optically active class of nanomaterials based on lanthanide‐doped lithium niobate nanoparticles, which simultaneously exhibit unprecedentedly efficient second and third harmonic generation, as well as up‐conversion photoluminescence, is reported. These dielectric nanoparticles retain their high nonlinear optical conversion efficiency both as powder and as aqueous colloidal solution. The high stability also allows for the fabrication of optically active biocompatible micron‐sized fibers and polymer‐based 3D‐printable objects, as well as for fingerprint detection. Finally, the first 8‐bit coding platform purely based on multimodal nonlinear optical activity originating from different parametric and nonparametric processes is demonstrated, showcasing the technological potential of these materials for both anti‐counterfeiting and advanced optical information processing. [ABSTRACT FROM AUTHOR]

Pyrroles and indoles bearing N‐allenyl tethers participate in a variety of iridium‐catalyzed cycloisomerization processes initiated by a C−H activation step, to deliver a diversity of synthetically relevant azaheterocyclic products. By appropriate selection of the ancillary ligand and the substitution pattern of the allene, the reactions can diverge from simple intramolecular hydrocarbonations to tandem processes involving intriguing mechanistic issues. Accordingly, a wide range of heterocyclic structures ranging from dihydro‐indolizines and pyridoindoles to tetrahydroindolizines, as well as cyclopropane‐fused tetrahydroindolizines can be obtained. Moreover, by using chiral ligands, these cascade processes can be carried out in an enantioselective manner. DFT studies provide insights into the underlying mechanisms and justify the observed chemo‐ regio‐ and stereoselectivities. [ABSTRACT FROM AUTHOR]