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The global expansion of photovoltaic (PV) power plants, especially in ecologically fragile regions like the Gobi Desert, highlights the suitability of such areas for large-scale PV development. The most direct impact of PV development in the Gobi Desert is temperature change that results from the land-use-induced albedo changes; however, the detailed and systemic understanding of the effects of PV expansion on land surface temperature remains limited. This study focuses on the 16 largest PV plants in the Chinese Gobi Desert, utilizing remote sensing data to assess their effects on land surface temperature. Our result showed a cooling effect during the daytime (−0.69 ± 0.10 °C), but a warming effect during the nighttime (0.23 ± 0.05 °C); the overall effect on the daily mean was a cooling effect (−0.22 ± 0.05 °C). Seasonal variations were observed, with the most significant cooling effect in autumn and the weakest in summer. The PV area was the most significant factor which influenced the temperature variation across PV plants. Our findings enrich our understanding of the environmental effects arising from the construction of PV plants and provide vital information for the design and management of increasingly renewable electricity systems globally. [ABSTRACT FROM AUTHOR]

Background: Long noncoding RNAs (lncRNAs) have emerged as key players in tumorigenesis and tumour progression. However, the biological functions and potential mechanisms of lncRNAs in colorectal cancer (CRC) are unclear. Methods: The novel lncRNA POU6F2-AS1 was identified through bioinformatics analysis, and its expression in CRC patients was verified via qRT–PCR and FISH. In vitro and in vivo experiments, such as BODIPY staining, Oil Red O staining, triglyceride (TAG) assays, and liquid chromatography mass spectrometry (LC-MS) were subsequently performed with CRC specimens and cells to determine the clinical significance, and functional roles of POU6F2-AS1. Biotinylated RNA pull-down, RIP, Me-RIP, ChIP, and patient-derived organoid (PDO) culture assays were performed to confirm the underlying mechanism of POU6F2-AS1. Results: The lncRNA POU6F2-AS1 is markedly upregulated in CRC and associated with adverse clinicopathological features and poor overall survival in CRC patients. Functionally, POU6F2-AS1 promotes the growth and lipogenesis of CRC cells both in vitro and in vivo. Mechanistically, METTL3-induced m6A modification is involved in the upregulation of POU6F2-AS1. Furthermore, upregulated POU6F2-AS1 could tether YBX1 to the FASN promoter to induce transcriptional activation, thus facilitating the growth and lipogenesis of CRC cells. Conclusions: Our data revealed that the upregulation of POU6F2-AS1 plays a critical role in CRC fatty acid metabolism and might provide a novel promising biomarker and therapeutic target for CRC. [ABSTRACT FROM AUTHOR]