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In late December 2019, a novel coronavirus, COVID −19 originated in Wuhan city of China, and significant improvement in not only the air quality but also the water quality. Therefore, the current study demonstrates the changes in water quality parameters of the Ghaggar river, Punjab, India. The variations in the water quality of the Ghaggar river have been examined during the pre-, during, and post-pandemic periods. The maximum temperature of the Ghaggar river for all monitoring stations was between 28 to 37°C during the pandemic period, whereas the maximum dissolved oxygen value varied from 3 to 7 mg/L. The maximum pH obtained from the monitoring stations was reported to be 7.7 to 8.0, except chhatbir monitoring station (7.6). The maximum biochemical oxygen demand for all monitoring stations was found to be between 18–53 mg/L. Strong positive correlations were observed between total coliform and fecal coliform for pre (0.76) and during (0.89) the pandemic periods. Similar significant positive correlations were recorded between BOD and conductivity for pre (0.75) and during (0.58) pandemic periods. [ABSTRACT FROM AUTHOR]

First case of severe acute respiratory syndrome coronavirus-2 was detected in Wuhan province of china. Within a year, the vaccine development process accelerated and emergency approval was rolled out for vaccines. Covishield, an adenovirus vector-based vaccine manufactured by Serum Institute of India, was granted emergency use approval by the subject expert committee under Drug Controller General of India in India in the month of January. Numerous adverse effects are still under study following vaccination. Among them, a very rare complication reported is Guillain-Barre syndrome (GBS). The relation between coronavirus disease 19 (COVID-19) vaccine and GBS is still not clear. Here, we present a case of a 32-year-old female with no comorbidities, presented with complaints of bilateral weakness in lower limbs which gradually progressed to upper limbs along with bilateral facial palsy. She had taken her first shot of Covishield vaccine last month. She has no risk factors for GBS, which suggests that it was caused by the vaccine. She was admitted to intensive care unit for further management. This report might help physicians to be more vigilant in evaluating GBS cases especially in the current COVID-19 pandemic era. [ABSTRACT FROM AUTHOR]