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Your search keyword '"Pelosi, Giuseppe"' showing total 7 results
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7 results on '"Pelosi, Giuseppe"'

4. Biphenotypic lung carcinoma with coexpression of TTF-1 and ΔNP63/P40 within most of the same individual cells: a further case confirming poor prognosis and a review of literature

Author

Marando, Alessandro, primary, Zagni, Moreno, additional, Negrelli, Mariachiara, additional, Valtorta, Emanuele, additional, Lauricella, Calogero, additional, Motta, Valentina, additional, Veronese, Silvio, additional, Cerea, Giulio, additional, Giannetta, Laura Giuseppina, additional, Ciarlo, Gabriele, additional, Signorelli, Diego, additional, Pizzutilo, Elio Gregory, additional, Bonoldi, Emanuela, additional, and Pelosi, Giuseppe, additional

Published
2024
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7. SMARCB1/INI1-deficient undifferentiated tumour of the thorax: a case report and review of the literature.

Author

Zagni M, Marando A, Negrelli M, Lauricella C, Motta V, Paglino G, Veronese S, Valtorta E, Bonoldi E, and Pelosi G

Subjects
Humans, Nuclear Proteins genetics, Nuclear Proteins deficiency, Male, Female, Biomarkers, Tumor analysis, Biomarkers, Tumor genetics, Middle Aged, Lung Neoplasms pathology, Lung Neoplasms genetics, Lung Neoplasms diagnosis, SMARCB1 Protein deficiency, SMARCB1 Protein genetics, Transcription Factors genetics, Transcription Factors deficiency, Thoracic Neoplasms pathology, Thoracic Neoplasms genetics, DNA Helicases deficiency, DNA Helicases genetics
Abstract

The 5th WHO classification of thoracic tumours includes thoracic SMARCA4-deficient undifferentiated tumour (SMARCA4-UT) among the "other epithelial tumours of the lung" chapter. Herein, we present a case of undifferentiated thoracic neoplasm with retention of SMARCA4 expression, lack of NUT fusion protein and loss of SMARCB1/INI1 expression. After presenting the clinical and pathological features of the tumour, we carried out a review of the literature on the same topic. Albeit very rare, we believe this entity should be included in the heterogeneous group of undifferentiated neoplasms of the thorax., (Copyright © 2024 Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology.)

Published
2024
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