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The purpose of the paper was to assess the impact of climate changes on agricultural development and food security in Ukraine and Slovakia using statistical data from Statistical Office of the Slovak Republic, State Statistics Service of Ukraine, Eurostat, Food and Agriculture Organization and other sources. The comparison method was used to evaluate changes in agricultural development indicators, as well as climate changes in 1998-2021 in Ukraine and Slovakia. The main indicators of agricultural development used in the research were agricultural raw materials exports(%), agricultural raw materials imports (%), agriculture value added (% of GDP), agriculture value added (annual % growth), agriculture value added (current US$), cereal production (metric tons), cereal yield (kg per hectare), crop production index, food production index. Correlation and regression equations were used to establish the relationship between climatic factors and agricultural development indicators. The multiple correlations between air temperature and indicators of agricultural development was r=0.75 for Ukraine, r=0.69 for Slovakia. Using neuromodeling tools, the indicators of cereal production volumes and cereals yields in Ukraine and Slovakia in 2024-2033 were predicted. Tables were used to summarize the results. In conclusion, it should be noted that climatic conditions should be analyzed in each sector of crop production, and measures should be taken to adapt technologies for the gradual expansion of obligations for the production and export of agricultural products to world markets. [ABSTRACT FROM AUTHOR]