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Uncontrollable bleeding caused by severe trauma is life-threatening. Therefore, it is of great significance to develop hemostatic materials that meet the rapid hemostasis of wounds. In this study, a water-triggered shape memory carboxylated cellulose nanofiber/sodium alginate/montmorillonite (CNSAMMTCa) composite hemostatic sponge was prepared, which can promote coagulation by concentrating the blood and activating intrinsic pathway. The anisotropic three-dimensional porous structure formed by directional freeze-drying technology improved the performance of composite sponges which showed good prospects in rapid hemostasis. The results showed that CNSAMMTCa composite sponge had good porous structure, water absorption ability, cytocompatibility and blood cell aggregation capacity. Simultaneously, we confirmed that CNSA3MMT2Ca has best coagulation performance in the mouse censored bleeding model and liver rupture bleeding model. Therefore, CNSAMMTCa composite hemostatic sponge is a safe and efficient rapid hemostatic material which is expected to become an alternative material for clinical hemostatic materials., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier B.V. All rights reserved.)

The growing application of flotation reagents (e.g., xanthate collectors) exacerbates water pollution in mined sites. Semiconductor-based photocatalysis is widely recognized as an efficient and green technology for treating mineral processing wastewater. However, the on-site practical application of powdery photocatalysts is still unsatisfactory because of their poor photochemical stability and limited recyclability. In this work, a flexible CdS/mixed cellulose composite membrane (CdS/MCM) was synthesized via a simple impregnation–precipitation process, and such a material has not been reported so far. CdS nanoparticles were embedded into the holes of MCM but did not block the membrane channels, avoiding the over-agglomeration of CdS nanoparticles. Compared with CdS powder, CdS/MCM had higher photocatalytic property. The degradation efficiency for sodium ethyl xanthate, potassium butyl xanthate, and potassium amyl xanthate over the optimized 0.175CdS/MCM exceeded 96%. Moreover, the separation of CdS/MCM from the pollution solution was easy, and CdS/MCM could be reused more than five times without any deactivation. This work opens new avenues in beneficiation wastewater treatment by rationally designing high-performance, low-cost CdS/MCM materials. [ABSTRACT FROM AUTHOR]

Hemostasis of deep irregular wounds is a severe problem in clinical practice. The development of rapid-acting hemostatic agents for deep and irregular wound is urgently needed. Here, sodium alginate/carboxycellulose/polydopamine (SA/CNF/PDA) microspheres was prepared by reverse emulsification and crosslinking with Ca2+, and SA/CNF/PDA composite hemostatic microspheres with porous structure were obtained by freeze-drying. SA/CNF/PDA composite hemostatic microspheres exhibited excellent porosity and water absorption which could rapidly absorb blood on the wound surface. Moreover, SA/CNF/PDA composite microspheres demonstrated remarkable hemostatic capabilities both in vitro and in vivo. It exhibited strong hemostatic performance in models of mouse tail-break and liver damage. Especially in liver injury model, it was completely hemostatic in 95 s, and blood loss (19.3 mg). The hemostatic efficacy of the SA/CNF/PDA composite microspheres was amplified through the stimulation of both exogenous and endogenous coagulation pathways. Therefore, SA/CNF/PDA composite hemostatic microspheres are suitable for rapid hemostasis of deep irregular wounds which are potential rapid hemostatic material for surgical application. • SA/CNF/PDA hemostatic microsphere was obtained by reverse emulsification and freeze-drying. • SA/CNF/PDA microsphere stopped bleeding within 95 s in liver injury model. • The activation of exogenous and endogenous coagulation pathways were activated. [ABSTRACT FROM AUTHOR]