1. Dosimetry and treatment efficiency of SBRT using TaiChiB radiotherapy system for two-lung lesions with one overlapping organs at risk.
- Author
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Duan, Yanhua, Feng, Aihui, Wang, Hao, Chen, Hua, Gu, Hengle, Shao, Yan, Huang, Ying, Shen, Zhenjiong, Kong, Qing, and Xu, Zhiyong
- Subjects
MEDICAL dosimetry ,LUNGS ,STEREOTACTIC radiotherapy ,RADIOTHERAPY ,SPINAL cord ,ROTATIONAL motion - Abstract
Purpose: This study aims to assess the dosimetry and treatment efficiency of TaiChiB-based Stereotactic Body Radiotherapy (SBRT) plans applying to treat two-lung lesions with one overlapping organs at risk. Methods: For four retrospective patients diagnosed with two-lung lesions each patient, four treatment plans were designed including Plan
Edge , TaiChiB linac-based, RGS-based, and a linac-RGS hybrid (PlanTCLinac , PlanTCRGS , and PlanTCHybrid ). Dosimetric metrics and beam-on time were employed to evaluate and compare the TaiChiB-based plans against PlanEdge . Results: For Conformity Index (CI), PlanTCRGS outperformed all other plans with an average CI of 1.06, as opposed to PlanEdge′ s 1.33. Similarly, for R50 % , PlanTCRGS was superior with an average R50 % of 3.79, better than PlanEdge′ s 4.28. In terms of D2 cm , PlanTCRGS also led with an average of 48.48%, compared to PlanEdge′ s 56.25%. For organ at risk (OAR) sparing, PlanTCRGS often displayed the lowest dosimetric values, notably for the spinal cord (Dmax 5.92 Gy) and lungs (D1500cc 1.00 Gy, D1000cc 2.61 Gy, V10 Gy 15.14%). However, its high Dmax values for the heart and great vessels sometimes exceeded safety thresholds. PlanTCHybrid presented a balanced approach, showing doses comparable to or better than PlanEdge without crossing safety limits. In terms of beam-on time, PlanTCLinac emerged as the most efficient treatment option in three out of four cases, followed closely by PlanEdge in one case. PlanTCRGS , despite its dosimetric advantages, was the least efficient, recording notably longer beam-on times, with a peak at 33.28 minutes in Case 2. Conclusion: For patients with two-lung lesions treated by SBRT whose one lesion overlaps with OARs, the PlanTCHybrid delivered by TaiChiB digital radiotherapy system can be recommended as a clinical option. [ABSTRACT FROM AUTHOR]- Published
- 2024
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