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1. Switching from prednisolone to dexamethasone in difficult-to-treat rheumatoid arthritis.

Author

Kerstens, Floor, Spijkers, Karin, Wolthuis, David, Boers, Maarten, Herwaarden, Noortje van, and Cate, David ten

Subjects
GLUCOCORTICOIDS, PREDNISOLONE, GENERIC drug substitution, DEXAMETHASONE, BIOAVAILABILITY, GENETIC variation, ISOENZYMES, RHEUMATOID arthritis, PHARMACODYNAMICS
Abstract

The article reports a response after switching from prednisole to dexamethasone in three D2T-RA patients with active disease despite prednisolone. Topics discussed include possible mechanisms why response to different glucocorticoids (GCs) may vary, pharmacodynamic differences between GCs, and characteristics of 3 ACPA-positive patients switched from prednisolone to dexamethasone.

Published
2024
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