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BACKGROUND: Beamforming is vital for medical ultrasound imaging systems. The generalized sidelobe canceller (GSC) beamforming can improve the image quality of lateral resolution, but its performance improvement in contrast and robustness is limited. OBJECTIVE: This paper proposes an improved generalized sidelobe canceller algorithm based on multi-apodization with cross-correlation (MAXB-IGSC), which aims to improve the contrast and robustness of ultrasound imaging while maintaining the high image resolution and background speckle quality of GSC. METHODS: The proposed MAXB-IGSC uses multiple pairs of complementary received apodization functions to process the echo data individually to obtain multiple pairs of data sets. The average of their normalized cross-correlation coefficients is then calculated and utilized to determine the adaptive subarray length of the GSC covariance matrix and weights the output of the improved GSC. RESULTS: The MAXB-IGSC improves the contrast ratio (CR) by 171.18% in anechoic cyst simulation and by 91.23%/130.97%/171.76% in geabr_0 (a dataset from the University of Michigan) experiment compared with GSC, respectively. Furthermore, MAXB-IGSC exhibits significant noise immunity, which greatly improves the robustness of the imaging. The technology also maintains the brightness and uniformity of the background speckle. CONCLUSION: The proposed MAXB-IGSC has potential for obtaining high-quality ultrasound images in clinical applications. [ABSTRACT FROM AUTHOR]

Ultrasound plane-wave imaging has the advantage of high frame rate in addition to high data volume. High data sampling rates and large amounts of data storage can become bottlenecks in ultrasound system design. Although compressed sensing technology can help reduce the burden of sampling and transmission, it achieves relatively low image quality because of its reliance solely on signal sparsity. Therefore, we proposed reconstructing the ultrasound signal by applying additional prior knowledge, such as plane-wave imaging and its echo characteristics. Inspired by multi-hypothesis prediction methods in video compression coding, the plane-wave multi-hypothesis prediction compressed sensing reconstruction method was proposed to improve the accuracy of reconstructions. We applied multi-hypothesis prediction and residual reconstruction on the plane wave to enhance the quality of reconstruction and correct predicted values. Also, to acquire high-quality hypotheses, two hypothesis acquisition schemes were evaluated, constructing search windows on both preceding and subsequent frames as well as the reference frame. Compared with traditional reconstruction methods that rely on sparsity, multi-hypothesis prediction compressed sensing methods can reduce signal reconstruction errors and significantly eliminate image artifacts. Furthermore, by using improved hypotheses, signal reconstruction and image quality can be enhanced, resulting in higher contrast. Comparative simulation experimental results based on the publicly available Plane-Wave Imaging Challenge in Medical Ultrasound (PICMUS) and acoustic radiation force imaging data sets demonstrate that the proposed method outperforms other methods in both reconstruction errors and image quality. This helps to reduce the complexity of sampling and transmission of the ultrasound system. [ABSTRACT FROM AUTHOR]