1. Mesenchymal stem cell therapy for COVID-19 infection.
- Author
-
Alavi-Dana, Seyyed Mohammad Matin, Gholami, Yazdan, Meghdadi, Mohammadreza, Fadaei, Mohammad Saleh, and Askari, Vahid Reza
- Subjects
- *
MESENCHYMAL stem cells , *COVID-19 , *COVID-19 treatment , *STEM cell treatment , *CYTOKINE release syndrome - Abstract
COVID-19 emerged in December 2019 in Wuhan, China, spread worldwide rapidly, and caused millions of deaths in a short time. Many preclinical and clinical studies were performed to discover the most efficient therapy to reduce the mortality of COVID-19 patients. Among various approaches for preventing and treating COVID-19, mesenchymal stem cell (MSC) therapy can be regarded as a novel and efficient treatment for managing COVID-19 patients. In this review, we explain the pathogenesis of COVID-19 infection in humans and discuss the role of MSCs in suppressing the inflammation and cytokine storm produced by COVID-19. Then, we reviewed the clinical trial and systematic review studies that investigated the safety and efficacy of MSC therapy in the treatment of COVID-19 infection. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF