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Copyright of Modern Preventive Medicine is the property of Modern Preventive Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the feasibility of utilizing three-dimensional (3D) printing technology for designing a lateral closing wedge osteotomy plate for assisting in osteotomy for cubitus varus deformity in children. Methods Retrospective analysis was conducted for the relevant clinical data of 45 children of cubitus varus deformity treated with the assistance of a 3D printed lateral closing wedge osteotomy plate from January 2020 to January 2022 in the pediatric orthopaedic ward of Chia Tai Shaoyang Orthopedic Hospital. There were 35 boys and 10 girls. The involved side was left (n=24) and right ( n=21). Perioperative values of carrying angle, anteversion angle and range of motion of elbow joint were measured. Elbow joint function was assessed by the Oppenheim Elbow Function Score. Results At the last follow-up, carrying angle of affected elbow joint was (11.3±1.6)°. There was no statistically significant difference as compared to unaffected side (P=0.085>0.05). Maximal extension angle of affected limb at the last follow-up ranged from -10° to 15° (average 3.7°) and maximal flexion angle ranged from 125° to 145° (average 134.6°). There was no statistically significant difference as compared to unaffected side ( P=0.12>0.05). According to the Oppenheim Elbow Function Score, the excellent/decent rate was 93%. Conclusions For cubitus varus deformity in children, using a 3D printed lateral closing wedge osteotomy plate for assisting in osteotomy may offer a simpler, more accurate and mini-invasive correction, achieving favorable clinical outcomes. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Chongqing University of Technology (Natural Science) is the property of Chongqing University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the vitamin D nutritional status and influencing factors of primary and middle school students in poverty areas of Guizhou Province, and to provide scientific basis for the development of targeted nutritional improvement measures. Methods A total of 2,519 students from 4 primary and4 middle schools in 9 key monitoring counties (districts) in Guizhou Province, where the Nutrition Improvement Program for Rural Compulsory Education Students was implemented in 2023, were selected for questionnaire surveys, physical examinations, and blood biochemistry tests using multistage cluster sampling methods. Multifactorial logistic regression was used to analyze the current status of vitamin D nutrition and its influencing factors. Results The average vitamin D level of primary and middle school students in poverty areas of Guizhou Province was (22. 59 ± 6. 66) ng/ml, and the rate of low vitamin D was 37. 51%. The prevalence of low vitamin D among female students (46. 17%) was higher than that of male students (29. 11%), and the difference was statistically significant 仗2 = 78. 213, P < 0. 001). There was a significant difference in the rate of low vitamin D among students in different regions 仗2 二 23. 454, P <0. 001), and the rate of low vitamin D tended to increase with age = 44. 905, P <0. 001). The results of multifactorial logistic regression analysis showed that, compared with the corresponding reference group, ethnic minorities (OR = 0. 706, 95% CI: 0. 590 - 0. 844), physical activity M60 min/d (OR = 0. 791, 95% CI: 0. 663 - 0. 943), and living in the countryside (OR - 0. 747, 95% CI: 0. 616 -0.906) were protective factors for low vitamin D levels; obesity (OR =2. 133, 95% C/: 1.390 - 3.272), female students (OR 二2. 238, 95% CI: 1.882 -2.662), the 11-13 years old group (OR =1. 849, 95% CI: 1. 521 - 2. 248) and the 14 - 17 years old group (OR = 2. 000, 95% CI: 1. 576 - 2. 539) were risk factors for low vitamin D levels. Conclusion High rates of low vitamin D among primary and middle school students in poverty areas of Guizhou Province require the development of personalized nutritional interventions to improve vitamin D nutritional status. [ABSTRACT FROM AUTHOR]

Objective: To prepare anti-human IgE nanobody by phage display technology, and to establish a method for hypersensitivity detection of cat dander specific IgE antibody. Methods: Allergen bio-information of cat was searched in WHO/IUIS Allergen Database. After synthesizing sequence, recombinant cat dander allergenic protein Fel d 1 was expressed and purified in prokaryotic expression system. Human IgE was used to immunize Bactrian camel and RNA were extracted from lymphocyte to construct phage display library. Library capacity, diversity and insertion rate were analyzed, anti-human IgE nanobody were obtained by screening and identification. A magnetic particle chemical method for cat dander specific IgE antibody detection was established using recombinant allergen-coupled magnetic particles and acridine ester-labeled nanobodies. Results: Capacity of phage display library was 1.88×108 cfu/ml, insertion rate was 93.6%, and purity of nanobody was >95%. Linear range of the method based on nanobody was 0.1~100 U/ml, who was consistent with ImmunoCAP detection system by clinical data. Conclusion: Nanobody-based cat dander specific IgE antibody hypersensitivity assay is successfully prepared, providing a technical basis for auxiliary diagnosis of cat allergic diseases. [ABSTRACT FROM AUTHOR]

Objective To investigate the correlation between 25-hydroxyvitamin D3 [25 (OH) D3] levels and insulin resistance, urine pH, and other factors in newly diagnosed type 2 diabetes mellitus (T2 DM) patients. Methods The levels of 25 (OH) D3 were measured in 325 non-diabetic patients (normal control group, n=325) and 208 newly diagnosed T2 DM patients (newly diagnosed T2 DM group, n=208) .Based on the levels of 25 (OH) D3,newly diagnosed T2 DM patients were divided into vitamin D deficiency group (n=92) and non-deficiency group (n=116). The level of25 (OH) D3 was considered deficient if it was ＜20 ng/mL and sufficient if it was 20-100 ng/mL. The correlation between 25 (OH) D3 and insulin resistance, urine pH, etc., was analyzed using SPSS 26.0.Results The level of 25 (OH) D3 in the newly diagnosed T2 DM group was higher than that in the normal control group (P ＜0.01); the age, glycated hemoglobin, insulin resistance index, urine pH, free triiodothyronine (FT3), and free thyroxine (FT4) in the deficiency group were higher than those in the non-deficiency group (P ＜0.05), while there was no statistically significant difference in pancreatic function index, fasting C-peptide, serum calcium, and thyroid-stimulating hormone (TSH) between the two groups (P＞ 0.05). Logistic regression analysis showed that glycated hemoglobin (OR=1.776, P ＜0.05) and insulin resistance index (OR=1.289, P ＜0.05) were risk factors for vitamin D deficiency in newly diagnosed T2 DM patients. Conclusion The level of 25 (OH) D3 in the newly diagnosed T2 DM group was lower than that in the normal control group. Higher glycated hemoglobin and insulin resistance index are risk factors for vitamin D deficiency in patients with T2 DM. [ABSTRACT FROM AUTHOR]

Copyright of China Synthetic Fiber Industry is the property of Sinopec Baling Petrochemical Company and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)