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This article discusses a case-control study that examined the prevalence of zinc hypersensitivity in patients with primary Sjögren syndrome (pSS). The study found that more than half of the patients with pSS were hypersensitive to zinc, compared to none of the healthy controls. The study suggests that zinc allergy may contribute to chronic inflammation in some patients with pSS and supports a connection between pSS and metal allergies. However, further research with larger sample sizes is needed to confirm these findings and understand the mechanisms involved. [Extracted from the article]