Search

Your search keyword '"Carson, Dennis A."' showing total 2 results
Start Over Author "Carson, Dennis A." Publication Year Range This year
2 results on '"Carson, Dennis A."'

2. Importance of Toll-Like Receptor 9 in Host Defense against M1T1 Group A Streptococcus Infections

Author

Zinkernagel, Annelies S., Hruz, Petr, Uchiyama, Satoshi, von Köckritz-Blickwede, Maren, Schuepbach, Reto A., Hayashi, Tomoko, Carson, Dennis A., and Nizet, Victor

Abstract

Timely recognition and elimination of invasive group A Streptococcus (GAS) by innate immunity is crucial to control infection. The intracellular pattern recognition receptor Toll-like receptor 9 (TLR9) promotes macrophage hypoxia-inducible factor-1α levels, oxidative burst and nitric oxide production in response to GAS. TLR9 contributes to GAS clearance in vivo in both localized cutaneous and systemic infection models.

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results