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Objectives: We evaluated studies that used the World Health Organization's (WHO) AirQ and AirQ+ tools for air pollution (AP) health risk assessment (HRA) and provided best practice suggestions for future assessments. Methods: We performed a comprehensive review of studies using WHO's AirQ and AirQ+ tools, searching several databases for relevant articles, reports, and theses from inception to Dec 31, 2022. Results: We identified 286 studies that met our criteria. The studies were conducted in 69 countries, with most (57%) in Iran, followed by Italy and India (~8% each). We found that many studies inadequately report air pollution exposure data, its quality, and validity. The decisions concerning the analysed population size, health outcomes of interest, baseline incidence, concentration-response functions, relative risk values, and counterfactual values are often not justified, sufficiently. Many studies lack an uncertainty assessment. Conclusion: Our review found a number of common shortcomings in the published assessments. We suggest better practices and urge future studies to focus on the quality of input data, its reporting, and associated uncertainties. [ABSTRACT FROM AUTHOR]

The first total synthesis of dragocins A−C, remarkable natural products containing an unusual C4' oxidized ribose architecture bridged by a polyhydroxylated pyrrolidine, is presented through a route featuring a number of uncommon maneuvers. Several generations towards the target molecules are presented, including the spectacular failure of a key C−H oxidation on a late‐stage intermediate. The final route features rapid, stereocontrolled access to a densely functionalized pyrrolidine and an unprecedented diastereoselective oxidative electrochemical cyclization to forge the hallmark 9‐membered ring. Preliminary studies suggest this electrochemical oxidation protocol is generally useful. [ABSTRACT FROM AUTHOR]

Younger and highly skilled generations are one of the major driving forces of a successful transformation to a circular economy (CE); therefore, this paper intends to assess the prevalent behaviour, attitudes, and knowledge of the CE by university students. The study focuses specifically on Portuguese students. Some new conclusions were added to the existent literature. Our conclusions show that, although students engage in several types of CE behaviour and have positive attitudes, these mostly include actions such as reducing food waste, recycling practices, or purchasing energy-efficient products. Circular consumption habits like remanufactured products, second-hand purchases, the sharing economy, and product-as-a-service systems (PSSs) still need further implementation. However, we determine that the level of knowledge of the CE goes beyond the conventional recycling premise. Moreover, we have included an innovative part, based on a probit model, by studying how knowledge of the CE affects students' behaviour and attitudes and conclude that it positively influences them. Other variables such as age, gender, and level of education are also found to influence actions and attitudes. As a result, this study can significantly improve the overview of the current situation and provide a starting point for measuring the effectiveness of future policies to be defined. [ABSTRACT FROM AUTHOR]

The first total synthesis of dragocins A-C, remarkable natural products containing an unusual C4' oxidized ribose architecture bridged by a polyhydroxylated pyrrolidine, is presented through a route featuring a number of uncommon maneuvers. Several generations towards the target molecules are presented, including the spectacular failure of a key C-H oxidation on a late-stage intermediate. The final route features rapid, stereocontrolled access to a densely functionalized pyrrolidine and an unprecedented diastereoselective oxidative electrochemical cyclization to forge the hallmark 9-membered ring. Preliminary studies suggest this electrochemical oxidation protocol is generally useful., (© 2024 Wiley‐VCH GmbH.)