1. Self-reported workplace bullying and subsequent risk of diagnosed mental disorders and psychotropic drug prescriptions: A register-based prospective cohort study of 75,252 participants.
- Author
-
Conway PM, Erlangsen A, Grynderup MB, Clausen T, Bjørner JB, Burr H, Francioli L, Garde AH, Hansen ÅM, Magnusson Hanson LL, Kirchheiner-Rasmussen J, Kristensen TS, Mikkelsen EG, Stenager E, Thorsen SV, Villadsen E, Høgh A, and Rugulies R
- Subjects
- Humans, Female, Male, Adult, Prospective Studies, Denmark epidemiology, Middle Aged, Risk Factors, Drug Prescriptions statistics & numerical data, Young Adult, Surveys and Questionnaires, Proportional Hazards Models, Adolescent, Aged, Bullying statistics & numerical data, Psychotropic Drugs adverse effects, Psychotropic Drugs therapeutic use, Mental Disorders epidemiology, Mental Disorders drug therapy, Registries, Workplace statistics & numerical data, Self Report
- Abstract
Background: Evidence concerning workplace bullying as a risk factor for mental disorders is currently limited to depressive disorders and mainly based on non-clinical assessments. This study aims to examine the prospective association of self-reported workplace bullying with different types of register-based hospital-diagnosed mental disorders and redeemed psychotropic drug prescriptions., Methods: Using a cohort study design, we examined a pooled dataset of 75,252 participants from 14 questionnaire-based surveys conducted between 2004 and 2014. In the questionnaires, workplace bullying was measured by a single item. The questionnaires were linked to Danish registers on hospital-diagnosed mental disorders and redeemed psychotropic drug prescriptions up to 2016. Data were analysed by multivariate Cox proportional hazard models, including only participants without a history of mental disorders or prescriptions since 1995., Results: After adjustment for sex, age, marital and socio-economic status, workplace bullying was associated with an excess risk of any mental disorder (HR 1.37; 95 % CI: 1.17-1.59) as well as mood disorders and neurotic, stress-related, and somatoform disorders. In stratified analyses, this association were statistically significant only among women. Workplace bullying was also associated with any psychotropic drug prescription (fully-adjusted HR 1.43; 95 % CI: 1.35-1.53). This association was observed in both sexes and for all prescriptions, including anxiolytics, hypnotics and sedatives, antidepressants, and nootropics., Limitations: Firm conclusions about sex-related differences cannot be drawn. Residual confounding by unmeasured factors such as personality cannot be ruled out., Conclusions: Workplace bullying was associated with higher risks of diagnosed mental disorders among women and psychotropic drug prescriptions in both sexes., Competing Interests: Declaration of competing interest None., (Copyright © 2024. Published by Elsevier B.V.)
- Published
- 2025
- Full Text
- View/download PDF