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En este trabajo pretendemos mostrar que la influyente tesis historiográfica de la “filosofía como forma de vida” de Pierre Hadot según la cual, el sello distintivo de la filosofía antigua fue la consistencia entre vida y doctrina, no es una tesis empírica rastreable históricamente, sino un ejemplar más de la denominada “falacia normativista” a través de la cual Hadot proyectó su concepción de la filosofía proveniente del monacato católico y del existencialismo. Consideramos que sin este importante apoyo el ideal mismo de consistencia entre vida y doctrina pierde una de sus principales bazas. Finalmente, y apelando a evidencia empírica reciente, mostramos que dicho ideal tampoco se concretiza en nuestros días.

Summary: Background: The proportion of people living with HIV (PLWHIV) co-infected with HCV in Mexico was unknown. Our aim was to estimate the seroprevalence of HCV among adults with HIV in Mexico. Methods: Using a complex-survey design, we collected blood samples and applied structured questionnaires between May 2nd, 2019 and February 17th, 2020 in a nationally, representative sample of adults receiving care for HIV-infection in 24 randomly selected HIV-care centres in 8 socio-demographically regions in Mexico. We tested serum for anti-HCV IgG antibodies and collected data on risky exposures. We estimated the seroprevalence of HCV and associated exposures using regression models and the Taylor linearization method to account for the cluster effect by region and centre. Findings: We collected blood samples of 2545 participants. Most participants were men (75.8%) with a median age of 37 years. The estimated seroprevalence of HCV is 3.9% (95% CI 3.1%–4.7%). Only 39 of 99 participants (40%) with HCV antibodies had active replication determined by RNA quantification. Seroprevalence of HCV was significantly higher among people with life-time history of imprisonment (9%, 95% CI 4.4%–13.6%), tattoo use (5.9%, 95% CI 3.9%–8%), and lifetime (22.3%, 95% CI 12.1%–32.6%) and recent (49.3%, 95% CI 18.3%–80.3%) injecting-drug use. Interpretation: Seroprevalence of HCV infection among PLWHIV in Mexico is ten times as high as the seroprevalence for the general population. The national program for HCV elimination focused in PLWHIV should target people that use injecting drugs and living in prisons. Funding: Abbvie Farmacéuticos, S.A de C.V Mexico through Investigator Initiated Study (2018).