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1. Type of calcineurin inhibitor and long-term outcomes following liver transplantation in patients with primary biliary cholangitis – an ELTR study

Author

Mirza, Darius, Heneghan, Michael, Lodge, Peter, Oniscu, Gabriel, Thorburn, Douglas, Allison, Michael, Pratschke, Johann, Manas, Derek, Bennet, William, Line, Pal-Dag, Hot, Emir, Zieniewicz, Krzysztof, Ericzon, Bo Goran, Fronek, Jiri, Klempnauer, Jurgen L., Rasmussen, Allan, Romagnoli, Renato, Nemec, Petr, Nordin, Arno, Paul, Andreas, De Simone, Paolo, Porte, R.J., Berlakovich, Gabriela, Cherqui, Daniel, Pirenne, Jacques, Sokal, Etienne, Rossi, Giorgio, Candinas, Daniel, Bachellier, Philippe, Rummo, Oleg, Boudjema, Karim, Mrzljak, Anna, Soubrane, Olivier, Metselaar, Herold, Schneeberger, Stefan, Navarro, Francis, Berney, Thierry, Duvoux, Christophe, Colledan, Michele, De Carlis, Luciano, Boillot, Olivier, Hardwigsen, Jean, Pruvot, Francois Rene, Suc, Bertrand, Vivarelli, Marco, Clavien, Pierre Alain, Lang, Hauke, Kosieradzki, Maciej, Berrevoet, Frederik, Heyd, Bruno, Cescon, Matteo, Chiche, Laurence, Kochs, Eberhard, Baccarani, Umberto, Detry, Olivier, Bartels, Michael, Rossi, Massimo, Scatton, Olivier, Papanikolaou, Vasileios, Alwayn, Ian, Schemmer, Peter, Senninger, N., Ducerf, Christian, Di Benedetto, Fabrizio, Tisone, Giuseppe, Nadalin, Silvio, Mathe, Zoltan, Ribnikar, Marija, Settmacher, Utz, Becker, Thomas, Silva, Nuno, Daniel, Jorge, Popescu, Irinel, Lucidi, Valerio, Bechstein, Wolf O., Decaens, Thomas, Gugenheim, Jean, Gruttadauria, Salvatore, Zamboni, Frausto, Zeytunlu, Murat, Kalff, Jorg C., Vali, Toomas, Tokat, Yaman, Klar, Ernst, Janek, Julius, Kilic, Murat, Katzarov, Krum, Fisher, Lutz, Buc, Emmanuel, Castagneto, Marco, Unek, Tarkan, Spassov, Lubomir, Stippel, Dirk, Bruns, Christiane, Schlitt, Hans, Salame, Ephrem, Kalicinski, Piotr, Acarli, Koray, van Hooff, Maria C., de Veer, Rozanne C., Karam, Vincent, Adam, Rene, Taimr, Pavel, Polak, Wojciech G., Pashtoun, Hasina, Murad, Sarwa Darwish, Corpechot, Christophe, Oniscu, Gabriel C., Metselaar, Herold J., den Hoed, Caroline M., and van der Meer, Adriaan J.

Published
2024
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2. Evaluation of a delayed liver transplantation strategy for patients with HCC receiving bridging therapy: the DELTA-HCC study

Author

Lamarque, Catherine, Segaux, Lauriane, Bachellier, Philippe, Buchard, Benjamin, Chermak, Faiza, Conti, Filomena, Decaens, Thomas, Dharancy, Sébastien, Di Martino, Vincent, Dumortier, Jérôme, Francoz-Caudron, Claire, Gugenheim, Jean, Hardwigsen, Jean, Muscari, Fabrice, Radenne, Sylvie, Salamé, Ephrem, Uguen, Thomas, Ursic-Bedoya, José, Antoine, Corinne, Deshayes, Aurélie, Jacquelinet, Christian, Natella, Pierre-André, Leroy, Vincent, Cherqui, Daniel, Oubaya, Nadia, and Duvoux, Christophe

Published
2024
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3. THU-494 Selective internal radiation therapy for unresectable hepatocellular carcinoma in a tertiary center in France, update and final analysis

Author

Regnault, Hélène, primary, Chalaye, Julia, additional, Galletto, Athena, additional, Perrin, Clara, additional, Amaddeo, Giuliana, additional, Lequoy, Marie, additional, Kobeiter, Hicham, additional, Mule, Sebastien, additional, Reizine, Edouard, additional, Itti, Emmanuel, additional, Duvoux, Christophe, additional, Laurent, Alexis, additional, Sommacale, Daniele, additional, Leroy, Vincent, additional, Luciani, Alain, additional, Derbel, Haytham, additional, Calderaro, Julien, additional, Tacher, Vania, additional, and Raffaele, Brustia, additional

Published
2024
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4. SAT-010 Elaboration of a one-year mortality score for first elective liver transplantation recipients over 60 years based on the results of the french national cohort between 2007 and 2017

Author

Labruyere, Marie, primary, Sow, Amadou-Khalilou, additional, Antoine, Corinne, additional, Dharancy, Sebastien, additional, Dumortier, Jérôme, additional, Turco, Celia, additional, Di Martino, Vincent, additional, Weil-Verhoeven, Delphine, additional, Houssel-Debry, Pauline, additional, Conti, Filomena, additional, Francoz, Claire, additional, Pageaux, Georges-Philippe, additional, Mabrut, Jean-Yves, additional, Salamé, Ephrem, additional, Faitot, François, additional, Coilly, Audrey, additional, Hardwigsen, Jean, additional, Decaens, Thomas, additional, Chermak, Faiza, additional, Muscari, Fabrice, additional, Anty, Rodolphe, additional, Duvoux, Christophe, additional, Abergel, Armand, additional, Franza, Anne Minello, additional, Binquet, Christine, additional, and Latournerie, Marianne, additional

Published
2024
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6. FRI-171 Paediatric solid organ transplant recipients (SOTR) demonstrate greater serological response to initial SARS-CoV-2 vaccination than adult SOTR, and comparable rates of antibody degradation

Author

Ballester, María Pilar, primary, Laue, Tobias, additional, Meoli, Lilianeleny, additional, Uson, Eva, additional, Mutschler, Frauke, additional, Grabitz, Carl, additional, McLin, Valérie, additional, D'Antiga, Lorenzo, additional, Pujadas, Montserrat, additional, Carvalho-Gomes, Ângela, additional, Sahuco, Iván, additional, Bono, Ariadna, additional, D'Amico, Federico, additional, Viganò, Raffaella, additional, Sempere, Elena Diago, additional, Tormo, Beatriz, additional, Inglese, Elvira, additional, Martinez, Dani, additional, Riva, Antonio, additional, Sharma, Rajni, additional, Tsou, Hio Lam Phoebe, additional, Harris, Nicola, additional, Broekhoven, Annelotte, additional, Kikkert, Marjolein, additional, Morales, Shessy, additional, Myeni, Sebenzile, additional, Barciela, Mar Riveiro, additional, Palom, Adriana, additional, Zeni, Nicola, additional, Brocca, Alessandra, additional, Cussigh, Annarosa, additional, Cmet, Sara, additional, Escudero-García, Desamparados, additional, Stocco, Matteo, additional, Natola, Leonardo, additional, Ieluzzi, Donatella, additional, Paon, Veronica, additional, Sangiovanni, Angelo, additional, Farina, Elisa, additional, Benedetto, Clara Di, additional, Sanchez-Torrijos, Yolanda María, additional, Valera, Ana Lucena, additional, Roman, Eva, additional, Sanchez, Elisabet, additional, Sánchez-Aldehuelo, Rubén, additional, López-Cardona, Julia, additional, Canas-Perez, Itzel, additional, Jackson, Christine, additional, Jeyanesan, Dhaarica, additional, Morocho, Alejandro Esquivel, additional, Cola, Simone Di, additional, Lapenna, Lucia, additional, Zaccherini, Giacomo, additional, Bongiovanni, Deborah, additional, Zanaga, Paola, additional, Sayaf, Katia, additional, Hossain, Sabir, additional, Crespo, Javier, additional, Robles-Díaz, Mercedes, additional, Madejón, Antonio, additional, Degroote, Helena, additional, Fernández, Javier, additional, Korenjak, Marko, additional, Verhelst, Xavier, additional, Garcia-Samaniego, Francisco Javier, additional, Andrade, Raul J., additional, Iruzubieta, Paula, additional, Wright, Gavin, additional, Caraceni, Paolo, additional, Merli, Manuela, additional, Patel, Vishal C., additional, Gander, Amir, additional, Albillos, Agustín, additional, Soriano, German, additional, Donato, Maria Francesca, additional, Sacerdoti, David, additional, Toniutto, Pierluigi, additional, Buti, Maria, additional, Duvoux, Christophe, additional, Grossi, Paolo Antonio, additional, Berg, Thomas, additional, Polak, Wojciech, additional, Puoti, Massimo, additional, Bosch, Anna, additional, Belli, Luca Saverio, additional, Burra, Patrizia, additional, Russo, Francesco Paolo, additional, Coenraad, Minneke, additional, Panero, José Luis Calleja, additional, Perricone, Giovanni, additional, Chokshi, Shilpa, additional, Berenguer, Marina, additional, Clària, Joan, additional, Moreau, Richard, additional, Arroyo, Vicente, additional, Angeli, Paolo, additional, Sanchez, Cristina, additional, Ampuero, Javier, additional, Piano, Salvatore, additional, and Nicastro, Emanuele, additional

Published
2024
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7. GS-010 Early liver transplantation for severe alcohol-related hepatitis: long-term data of the french-belgian controlled study (QuickTrans)

Author

Louvet, Alexandre, primary, Favier, Laurie, additional, Labreuche, Julien, additional, Moreno, Christophe, additional, Vanlemmens, Claire, additional, Moirand, Romain, additional, Wandji, Line Carolle Ntandja, additional, Feray, Cyrille, additional, Dumortier, Jérôme, additional, Pageaux, Georges-Philippe, additional, Bureau, Christophe, additional, Chermak, Faiza, additional, Duvoux, Christophe, additional, Thabut, Dominique, additional, Hilleret, Marie-Noëlle, additional, Carbonell, Nicolas, additional, Salamé, Ephrem, additional, Anty, Rodolphe, additional, Gournay, Jérôme, additional, Delwaide, Jean, additional, Silvain, Christine, additional, Lassailly, Guillaume, additional, Dharancy, Sébastien, additional, Khac, Eric Nguyen, additional, Samuel, Didier, additional, Duhamel, Alain, additional, and Mathurin, Philippe, additional

Published
2024
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8. SAT-048 Long-term mortality and risk factors associated with mortality after liver transplantation in the modern era

Author

Meszaros, Magdalena, primary, Coilly, Audrey, additional, Francoz, Claire, additional, Conti, Filomena, additional, Duvoux, Christophe, additional, Dumortier, Jérôme, additional, Antonini, Teresa, additional, Dharancy, Sébastien, additional, Hilleret, Marie-Noëlle, additional, Del Bello, Arnaud, additional, Anty, Rodolphe, additional, Weil-Verhoeven, Delphine, additional, Latournerie, Marianne, additional, Houssel-Debry, Pauline, additional, Dassetto, Clara, additional, Chermak, Faiza, additional, Faitot, François, additional, Elkrief, Laure, additional, Perignon, Claire, additional, Abergel, Armand, additional, Charpy, Flora, additional, Molinari, Nicolas, additional, and Pageaux, Georges-Philippe, additional

Published
2024
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9. LBP-026 The global prospective observational study to evaluate the role of ‘liver transplantation in patients with cirrhosis and severe acuteon-chronic liver failure (CHANCE)’: study design, demographics and overall outcome

Author

Gustot, Thierry, primary, Bernal, William, additional, Fernández, Javier, additional, Diaz, Juan Manuel, additional, de la Peña-Ramirez, Carlos, additional, Farias, Alberto, additional, Zitelli, Patricia Momoyo, additional, Kuo, Alexander, additional, Nissen, Nicholas, additional, Marciano, Sebastián, additional, Gadano, Adrian, additional, Westbrook, Rachel, additional, Bateman, Rebecca, additional, Rammohan, Ashwin, additional, Jothimani, Dinesh, additional, Sudhindran, Surendran, additional, Valsan, Arun, additional, Ruiz, Pablo, additional, Pagano, Giulia, additional, Bagulho, Luis, additional, Marques, Hugo Pinto, additional, Belli, Luca Saverio, additional, Perricone, Giovanni, additional, Selzner, Nazia, additional, Tsien, Cynthia, additional, Gallegos-Orozco, Juan F., additional, Kemmer, Nyingi, additional, Dhanireddy, Kiran, additional, Mendizaba, Manuel, additional, Pages, Josefina, additional, Lindenmeyer, Christina, additional, Eghtesad, Bijan, additional, Lucidi, Valerio, additional, Elkrief, Laure, additional, Raszeja-Wyszomirska, Joanna, additional, Anders, Margarita, additional, Nadalin, Silvio, additional, Siniscalchi, Antonio, additional, Tosetti, Giulia, additional, Vinaixa, Carmen, additional, Kriss, Michael, additional, Jalal, Prasun, additional, Michard, Baptiste, additional, Angeli, Paolo, additional, Castro-Narro, Graciela, additional, Boudjema, Karim, additional, Shetty, Kirti, additional, den Hoed, Caroline, additional, Carone, Lívia, additional, Yilmaz, Sezai, additional, Mattos, Angelo Z., additional, Martin-Mateos, Rosa, additional, Brol, Maximilian Joseph, additional, Yoshizumi, Tomoharu, additional, Durand, Francois, additional, Radenne, Sylvie, additional, Te, Helen, additional, Campos-Varela, Isabel, additional, Laleman, Wim, additional, Ohira, Masahiro, additional, Eguchi, Susumu, additional, Engelmann, Cornelius, additional, Braun, Felix, additional, Sinclair, Marie, additional, Bedoya, José Ursic, additional, Loinaz, Carmelo, additional, Perera, Thamara, additional, Soin, Arvinder Singh, additional, Liu, Ken, additional, Raevens, Sarah, additional, Bishop, Rebecca, additional, Simpson, Kenneth J., additional, Akamatsu, Nobuhisa, additional, Chien, Yong Chee, additional, Berlakovich, Gabriela, additional, Zuluaga, Juan Ignacio Marin, additional, Stein, Lance, additional, Tokat, Yaman, additional, Hernaez, Ruben, additional, Duvoux, Christophe, additional, Saliba, Faouzi, additional, McCaughan, Geoff, additional, Fondevila, Constantino, additional, Pomfret, Elizabeth, additional, Rela, Mohamed, additional, Sundaram, Vinay, additional, Claria, Joan, additional, Arroyo, Vicente, additional, Valles, Foix, additional, Martínez, Jorge Carlos, additional, Izquierdo-Bueno, Pedro, additional, Samuel, Didier, additional, Berenguer, Marina, additional, Bosch, Anna, additional, Sanchez, Cristina, additional, Polak, Wojciech, additional, Karvellas, Constantine, additional, Trebicka, Jonel, additional, Moreau, Richard, additional, and Jalan, Rajiv, additional

Published
2024
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10. LBO-004 Excess waitlist mortality and survival benefit of liver transplantation for patients with severe acute-on-chronic liver failure: Interim results of the CHANCE study

Author

Gustot, Thierry, primary, Bernal, William, additional, Fernández, Javier, additional, Diaz, Juan Manuel, additional, de la Peña-Ramirez, Carlos, additional, Farias, Alberto, additional, Zitelli, Patricia Momoyo, additional, Kuo, Alexander, additional, Nissen, Nicholas, additional, Marciano, Sebastián, additional, Gadano, Adrian, additional, Westbrook, Rachel, additional, Bateman, Rebecca, additional, Rammohan, Ashwin, additional, Jothimani, Dinesh, additional, Sudhindran, S, additional, Valsan, Arun, additional, Ruiz, Pablo, additional, Pagano, Giulia, additional, Bagulho, Luis, additional, Marques, Hugo Pinto, additional, Belli, Luca Saverio, additional, Perricone, Giovanni, additional, Selzner, Nazia, additional, Tsien, Cynthia, additional, Gallegos-Orozco, Juan F., additional, Kemmer, Nyingi, additional, Dhanireddy, Kiran, additional, Mendizabal, Manuel, additional, Pages, Josefina, additional, Lindenmeyer, Christina, additional, Eghtesad, Bijan, additional, Putignano, Antonella, additional, Elkrief, Laure, additional, Raszeja-Wyszomirska, Joanna, additional, Anders, Margarita, additional, Nadalin, Silvio, additional, Siniscalchi, Antonio, additional, Tosetti, Giulia, additional, Vinaixa, Carmen, additional, Kriss, Michael, additional, Jalal, Prasun, additional, Michard, Baptiste, additional, Angeli, Paolo, additional, Castro-Narro, Graciela, additional, Boudjema, Karim, additional, Shetty, Kirti, additional, den Hoed, Caroline, additional, Carone, Lívia, additional, Yilmaz, Sezai, additional, Zanotelli, Maria Lúcia, additional, Martin-Mateos, Rosa, additional, Brol, Maximilian Joseph, additional, Yoshizumi, Tomoharu, additional, Durand, Francois, additional, Radenne, Sylvie, additional, Te, Helen, additional, Campos-Varela, Isabel, additional, Laleman, Wim, additional, Ohira, Masahiro, additional, Eguchi, Susumu, additional, Engelmann, Cornelius, additional, Karvellas, Constantine, additional, Braun, Felix, additional, Sinclair, Marie, additional, Bedoya, José Ursic, additional, Loinaz, Carmelo, additional, Perera, Thamara, additional, Soin, Arvinder Singh, additional, Liu, Ken, additional, Raevens, Sarah, additional, Bishop, Rebecca, additional, Simpson, Kenneth J., additional, Akamatsu, Nobuhisa, additional, Chien, Yong Chee, additional, Berlakovich, Gabriela, additional, Zuluaga, Juan Ignacio Marin, additional, Stein, Lance, additional, Hernaez, Ruben, additional, Duvoux, Christophe, additional, Saliba, Faouzi, additional, Fondevila, Constantino, additional, McCaughan, Geoff, additional, Tokat, Yaman, additional, Pomfret, Elizabeth, additional, Rela, Mohamed, additional, Sundaram, Vinay, additional, Claria, Joan, additional, Arroyo, Vicente, additional, Valles, Foix, additional, Martínez, Jorge Carlos, additional, Izquierdo-Bueno, Pedro, additional, Samuel, Didier, additional, Berenguer, Marina, additional, Bosch, Anna, additional, Sanchez, Cristina, additional, Polak, Wojciech, additional, Trebicka, Jonel, additional, Moreau, Richard, additional, and Jalan, Rajiv, additional

Published
2024
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11. Type of calcineurin inhibitor and long-term outcomes following liver transplantation in patients with Primary Biliary Cholangitis- an ELTR study

Author

van Hooff, Maria C., primary, de Veer, Rozanne C., additional, Karam, Vincent, additional, Adam, Rene, additional, Taimr, Pavel, additional, Polak, Wojciech G., additional, Pashtoun, H., additional, Murad, Sarwa Darwish, additional, Corpechot, Christophe, additional, Mirza, Darius, additional, Heneghan, Michael, additional, Lodge, Peter, additional, Oniscu, Gabriel C., additional, Thorburn, Douglas, additional, Allison, Michael, additional, Metselaar, Herold J., additional, den Hoed, Caroline M., additional, van der Meer, Adriaan J., additional, Oniscu, Gabriel, additional, Pratschke, Johann, additional, Manas, Derek, additional, Bennet, William, additional, Line, Pal-Dag, additional, Hoti, Emir, additional, Zieniewicz, Krzysztof, additional, Ericzon, Bo Goran, additional, Fronek, Jiri, additional, Klempnauer, Jurgen L., additional, Rasmussen, Allan, additional, Romagnoli, Renato, additional, Nemec, Petr, additional, Nordin, Arno, additional, Paul, Andreas, additional, De Simone, Paolo, additional, Porte, R.J., additional, Berlakovich, Gabriela, additional, Cherqui, Daniel, additional, Pirenne, Jacques, additional, Sokal, Etienne, additional, Rossi, Giorgio, additional, Candinas, Daniel, additional, Bachellier, Philippe, additional, Rummo, Oleg, additional, Boudjema, Karim, additional, Mrzljak, Anna, additional, Soubrane, Olivier, additional, Metselaar, Herold, additional, Schneeberger, Stefan, additional, Navarro, Francis, additional, Berney, Thierry, additional, Duvoux, Christophe, additional, Colledan, Michele, additional, De Carlis, Luciano, additional, Boillot, Olivier, additional, Hardwigsen, Jean, additional, Pruvot, Francois Rene, additional, Suc, Bertrand, additional, Vivarelli, Marco, additional, Clavien, Pierre Alain, additional, Lang, Hauke, additional, Kosieradzki, Maciej, additional, Berrevoet, Frederik, additional, Heyd, Bruno, additional, Cescon, Matteo, additional, Chiche, Laurence, additional, Kochs, Eberhard, additional, Baccarani, Umberto, additional, Detry, Olivier, additional, Bartels, Michael, additional, Rossi, Massimo, additional, Scatton, Olivier, additional, Papanikolaou, Vasileios, additional, Alwayn, Ian, additional, Schemmer, Peter, additional, Senninger, N., additional, Ducerf, Christian, additional, Di Benedetto, Fabrizio, additional, Tisone, Giuseppe, additional, Nadalin, Silvio, additional, Mathe, Zoltan, additional, Ribnikar, Marija, additional, Settmacher, Utz, additional, Becker, Thomas, additional, Silva, Nuno, additional, Daniel, Jorge, additional, Popescu, Irinel, additional, Lucidi, Valerio, additional, Bechstein, Wolf O., additional, Decaens, Thomas, additional, Gugenheim, Jean, additional, Gruttadauria, Salvatore, additional, Zamboni, Frausto, additional, Zeytunlu, Murat, additional, Kalff, Jorg C., additional, Vali, Toomas, additional, Tokat, Yaman, additional, Klar, Ernst, additional, Janek, Julius, additional, Kilic, Murat, additional, Katzarov, Krum, additional, Fisher, Lutz, additional, Buc, Emmanuel, additional, Castagneto, Marco, additional, Unek, Tarkan, additional, Spassov, Lubomir, additional, Stippel, Dirk, additional, Bruns, Christiane, additional, Schlitt, Hans, additional, Salame, Ephrem, additional, Kalicinski, Piotr, additional, and Acarli, Koray, additional

Published
2024
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12. Selective internal radiation therapy for unresectable HCC: The SIRT downstaging study.

Author

Regnault, Hélène, Chalaye, Julia, Galetto-Pregliasco, Athena, Perrin, Clara, Derbel, Haytham, Amaddeo, Giuliana, Mulé, Sébastien, Lequoy, Marie, Kobeiter, Hicham, Reizine, Edouard, Itti, Emmanuel, Duvoux, Christophe, Laurent, Alexis, Leroy, Vincent, Sommacale, Daniele, Rasolonirina, Diana, Luciani, Alain, Calderaro, Julien, Tacher, Vania, and Brustia, Raffaele

Published
2024
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13. Autoimmune hepatitis recurrence after liver transplantation: “Les jeux sont faits”.

Author

Chouik, Yasmina, Corpechot, Christophe, Francoz, Claire, De Martin, Eleonora, Guillaud, Olivier, Abergel, Armand, Altieri, Mario, Barbier, Louise, Besch, Camille, Chazouillères, Olivier, Conti, Filomena, Dharancy, Sébastien, Durand, François, Duvoux, Christophe, Gugenheim, Jean, Hardwigsen, Jean, Hilleret, Marie-Noëlle, Houssel-Debry, Pauline, Kamar, Nassim, and Minello, Anne

Published
2024
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14. Recent outcomes of liver transplantation for Budd-Chiari syndrome: A study of the European Liver Transplant Registry (ELTR) and affiliated centers.

Author

Dongelmans E, Erler N, Adam R, Nadalin S, Karam V, Yilmaz S, Kelly C, Pirenne J, Acarli K, Allison M, Hakeem A, Dhakshinamoorthy V, Fedaruk D, Rummo O, Kilic M, Nordin A, Fischer L, Parente A, Mirza D, Bennet W, Tokat Y, Faitot F, Antonelli BB, Berlakovich G, Patch D, Berrevoet F, Ribnikar M, Gerster T, Savier E, Gruttadauria S, Ericzon BG, Valdivieso A, Cuervas-Mons V, Perez Saborido B, Croner RS, De Carlis L, Magini G, Rossi R, Popescu I, Razvan L, Schneeberger S, Blokzijl H, Llado L, Gomez Bravo MA, Duvoux C, Mezjlík V, Oniscu GC, Pearson K, Dayangac M, Lucidi V, Detry O, Rotellar F, den Hoed C, Polak WG, and Darwish Murad S

Subjects
Humans, Male, Female, Europe epidemiology, Adult, Middle Aged, Treatment Outcome, Young Adult, Adolescent, Retrospective Studies, Budd-Chiari Syndrome surgery, Liver Transplantation statistics & numerical data, Registries statistics & numerical data, Graft Survival
Abstract

Background and Aims: Management of Budd-Chiari syndrome (BCS) has improved over the last decades. The main aim was to evaluate the contemporary post-liver transplant (post-LT) outcomes in Europe., Approach and Results: Data from all patients who underwent transplantation from 1976 to 2020 was obtained from the European Liver Transplant Registry (ELTR). Patients < 16 years, with secondary BCS or HCC were excluded. Patient survival (PS) and graft survival (GS) before and after 2000 were compared. Multivariate Cox regression analysis identified predictors of PS and GS after 2000. Supplemental data was requested from all ELTR-affiliated centers and received from 44. In all, 808 patients underwent transplantation between 2000 and 2020. One-, 5- and 10-year PS was 84%, 77%, and 68%, and GS was 79%, 70%, and 62%, respectively. Both significantly improved compared to outcomes before 2000 ( p < 0.001). Median follow-up was 50 months and retransplantation rate was 12%. Recipient age (aHR:1.04,95%CI:1.02-1.06) and MELD score (aHR:1.04,95%CI:1.01-1.06), especially above 30, were associated with worse PS, while male sex had better outcomes (aHR:0.63,95%CI:0.41-0.96). Donor age was associated with worse PS (aHR:1.01,95%CI:1.00-1.03) and GS (aHR:1.02,95%CI:1.01-1.03). In 353 patients (44%) with supplemental data, 33% had myeloproliferative neoplasm, 20% underwent TIPS pre-LT, and 85% used anticoagulation post-LT. Post-LT anticoagulation was associated with improved PS (aHR:0.29,95%CI:0.16-0.54) and GS (aHR:0.48,95%CI:0.29-0.81). Hepatic artery thrombosis and portal vein thrombosis (PVT) occurred in 9% and 7%, while recurrent BCS was rare (3%)., Conclusions: LT for BCS results in excellent patient- and graft-survival. Older recipient or donor age and higher MELD are associated with poorer outcomes, while long-term anticoagulation improves both patient and graft outcomes., (Copyright © 2024 American Association for the Study of Liver Diseases.)

Published
2024
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15. Recipient age influences survival after liver transplant: Results of the French national cohort 2007-2017.

Author

Lerosey L, Ksiasek E, Abrahamowicz M, Antoine C, Dharancy S, Dumortier J, Doussot A, Di Martino V, Houssel-Debry P, Conti F, Francoz C, Pageaux GP, Salame E, Faitot F, Coilly A, Hardwigsen J, Decaens T, Chermak F, Muscari F, Anty R, Duvoux C, Abergel A, Minello A, Mouillot T, Binquet C, and Latournerie M

Subjects
Humans, Middle Aged, Male, Female, France epidemiology, Aged, Age Factors, Cross-Sectional Studies, Adult, Risk Factors, Postoperative Complications mortality, Survival Analysis, End Stage Liver Disease surgery, End Stage Liver Disease mortality, Transplant Recipients statistics & numerical data, Liver Transplantation mortality
Abstract

Background: In recent years, age at liver transplantation (LT) has markedly increased. In the context of organ shortage, we investigated the impact of recipient age on post-transplantation mortality., Methods: All adult patients who received a first LT between 2007 and 2017 were included in this cross-sectional study. Recipients' characteristics at the time of listing, donor and surgery data, post-operative complications and follow-up of vital status were retrieved from the national transplantation database. The impact of age on 5-year overall mortality post-LT was estimated using a flexible multivariable parametric model which was also used to estimate the association between age and 10-year net survival, accounting for expected age- and sex-related mortality., Results: Among the 7610 patients, 21.4% were aged 60-65 years, and 15.7% over 65. With increasing age, comorbidities increased but severity of liver disease decreased. Older recipient age was associated with decreased observed survival at 5 years after LT (p < .001), with a significant effect particularly during the first 2 years. The linear increase in the risk of death associated with age does not allow any definition of an age's threshold for LT (p = .832). Other covariates associated with an increased risk of 5-year death were dialysis and mechanical ventilation at transplant, transfusion during LT, hepatocellular carcinoma and donor age. Ten-year flexible net survival analysis confirmed these results., Conclusion: Although there was a selection process for older recipients, increasing age at LT was associated with an increased risk of death, particularly in the first years after LT., (© 2024 The Authors. Liver International published by John Wiley & Sons Ltd.)

Published
2024
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