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Bio-synthesized silver nanoparticles (AgNPs) were successfully obtained using the leaf extract from Ventilago maderaspatana. Extensive analysis was conducted to evaluate the physical and chemical characteristics of the bioderived AgNPs. XRD analysis confirmed their cubic structure, and revealed a well-defined size distribution with average crystallite size of 11.7 nm. FE-SEM and TEM images visually supported the observed size range. The presence of plant-mediated phytochemicals on the surface of AgNPs was confirmed through DLS, FTIR, and TGA/DTA studies. To assess their antidiabetic potential, rats were induced with streptozotocin, resulting in elevated levels of biochemical parameters associated with diabetes. Conversely, serum insulin levels (2.50 ± 0.55) and glucokinase activity (64.50 ± 8.66) decreased. However, treatment with AgNPs demonstrated a dose-dependent reduction in blood glucose, total protein, albumin, and HbA1c levels, effectively restoring them to normal ranges. Moreover, the treatment significantly increased insulin levels (7.55 ± 0.63) and glucokinase activity (121.50 ± 4.60), indicating the antidiabetic potential of V. maderaspatana-mediated AgNPs. Notably, the exitance of phytochemicals, like flavonoids and phenols, on the surface of AgNPs facilitated their ability to neutralize reactive oxygen species (ROS) through electron donation. This property enhanced their overall antidiabetic efficiency. [ABSTRACT FROM AUTHOR]

A pervasive sleep disorder named insomnia has been increasingly recognized as a major factor leading comorbidity in individuals suffering with mental health problems. The review article demonstrated the cause and impact of insomnia through literature on individuals who are already struggling with mental health issues. After a thorough database research, Studies evaluating the prevalence rates of insomnia across different mental health illnesses, such as anxiety, depression, schizophrenia, bipolar disorder, and post-traumatic stress disorder, were found. In addition to this, review article examines the duality of insomnia and mental health. It explains how insomnia worsens psychiatric symptoms while also exacerbating them. It also discusses how untreated insomnia can affect the development and prognosis of psychiatric disorders, as well as how treatment strategies can address both sleep disorders and psychiatric symptoms. Finally, it explores potential mechanisms that may be at play between insomnia and psychiatric disorders, including dysregulation of neurotransmitters, hypothalamic, pituitary, and adrenal functions, as well as cognitive and emotional processes. By understanding the complex relationship between insomnia and psychological health, holistic interventions can be developed that address both sleep disturbance and psychiatric symptoms, leading to improved well-being and overall quality of life. [ABSTRACT FROM AUTHOR]

Gum arabic also known as gum Acacia, Acacia Senegal and Arabic gum is a natural, edible, dietary fiber and polysaccharide consisting of an arabiono-galactan-protein complex. The term Arabic gum was proposed by European merchants. Two species of Acacia, Acacia seyal and Acacia Senegal are recommended to produce a gum. 80% gum is produced from Acacia Senegal which is widely distributed to Sudan, Africa, Japan, Nepal, and many other tropical and subtropic regions of the world. From ancient times, it has been used for many beneficial purposes. Anciently it was used to make mummies and in painting. Currently, it is widely used for food applications, clinical uses, and non-food applications. In food approaches, it is used as a flavoring agent, stabilizer, sweetener, and thickening agent. It is used for the formulation of ice creams, candies, jellies, soft drinks, beverages, desserts, and soup. In clinical uses, it is used due to its anti-inflammatory, anti-oxidant, anti-obesity, anti-diarrhea, immune-stimulant, analgesic, cardioprotective, hepatoprotective, renal protective, anticancerous, anti-ulcerative and for many other purposes due to diversity of potential. In non-food applications, it is used for the synthesis of syrups, tablets, lozenges, creams, lotions, paint, ink, glue, and ceramics. This review briefly covered the all area in which gum arabic is used widely due to its beneficial activities. [ABSTRACT FROM AUTHOR]

Cichoriumintybus L., often known as chicory, is a Mediterranean plant species that is a member of the Asteraceae family. It has been known to have therapeutic benefits for a very long time. C. intybus is unique among the six species of Cichorium that are grown in Europe and Asia because of its wide range of uses in conventional medicine. The plant has been used in many traditional medical systems, especially in India, where it has been used to treat a wide range of illnesses, from diabetes to wounds. Chicory contains a wide range of phytoconstituents, including cellulose, proteins, sugar, flavonoids, polyphenols, carotenoids, anthocyanins, tannins, coumarins, sesquiterpene lactones, fatty acids, cholins, benzo-isochromenes, alkaloids, vitamins, and minerals. The diverse ranges of therapeutic benefits associated with C. intybus are partly ascribed to this phytochemical composition. The pharmacological actions of chicory, which have been demonstrated to range from hepatoprotective to anti-inflammatory, demonstrate the plant's versatility and its potential to treat a variety of illnesses. This article offers a thorough investigation of C. intybus L.'s phytochemistry and pharmacological applications. This review attempts to be a useful resource for researchers, medical professionals, and practitioners interested in using Cichoriumintybus's medicinal properties for improving human health by compiling the body of knowledge on the botanical and chemical aspects of chicory as well as its therapeutic applications. [ABSTRACT FROM AUTHOR]

An annual herb is known as "Fumitory," Fumaria indica (Hausskn.) Pugsley (Fumariaceae), is a widespread weed in Pakistan's and India's plains. The plantis frequently employed in the Unani and Ayurvedic medical systems, both as a single herb and in different polyherbal preparations. It is helpful for aches, diarrhea, fever, influenza, liver issues, dyspepsia, constipation, vomiting, diuretic, anthelmintic, leukoderma, diaphoretic, blood purification, and for jaundice when combined with black pepper. It has several different chemical components, including carbohydrates, amino acids, proteins, phenolic compounds, alkaloids, flavonoids, terpenoids, glycosides, phytosterols, fixed oils, saponins, steroids, tannins, and more. According to research investigations, this plant has a wide range of pharmacological properties, including antioxidant, analgesic, anticancer, antidiabetic, antibacterial, aphrodisiac, and therapeutic effects on biliary disorders and irritable bowel syndrome. This review focused on the chemical components and pharmacological properties of this plant, which may be useful in future molecular and phytochemical research for the development of medication formulations for the treatment of various ailments. [ABSTRACT FROM AUTHOR]

Bio-synthesized silver nanoparticles (AgNPs) were successfully obtained using the leaf extract from Ventilago maderaspatana . Extensive analysis was conducted to evaluate the physical and chemical characteristics of the bioderived AgNPs. XRD analysis confirmed their cubic structure, and revealed a well-defined size distribution with average crystallite size of 11.7  nm. FE-SEM and TEM images visually supported the observed size range. The presence of plant-mediated phytochemicals on the surface of AgNPs was confirmed through DLS, FTIR, and TGA/DTA studies. To assess their antidiabetic potential, rats were induced with streptozotocin, resulting in elevated levels of biochemical parameters associated with diabetes. Conversely, serum insulin levels (2.50 ± 0.55) and glucokinase activity (64.50 ± 8.66) decreased. However, treatment with AgNPs demonstrated a dose-dependent reduction in blood glucose, total protein, albumin, and HbA1c levels, effectively restoring them to normal ranges. Moreover, the treatment significantly increased insulin levels (7.55 ± 0.63) and glucokinase activity (121.50 ± 4.60), indicating the antidiabetic potential of V. maderaspatana -mediated AgNPs. Notably, the exitance of phytochemicals, like flavonoids and phenols, on the surface of AgNPs facilitated their ability to neutralize reactive oxygen species (ROS) through electron donation. This property enhanced their overall antidiabetic efficiency.