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1. Cytogenetic abnormalities predict survival after allogeneic hematopoietic stem cell transplantation for pediatric acute myeloid leukemia: a PDWP/EBMT study

Author

Sharma, Akshay, Galimard, Jacques-Emmanuel, Pryce, Angharad, Bhoopalan, Senthil Velan, Dalissier, Arnaud, Dalle, Jean-Hugues, Locatelli, Franco, Jubert, Charlotte, Mirci-Danicar, Oana, Kitra-Roussou, Vassiliki, Bertrand, Yves, Fagioli, Franca, Rialland, Fanny, Biffi, Alessandra, Wynn, Robert F., Michel, Gérard, Tambaro, Francesco Paolo, Al-Ahmari, Ali, Tbakhi, Abdelghani, Furness, Caroline L., Diaz, Miguel Angel, Sedlacek, Petr, Bodova, Ivana, Faraci, Maura, Rao, Kanchan, Kleinschmidt, Katharina, Petit, Arnaud, Gibson, Brenda, Bhatt, Neel S., Kalwak, Krzysztof, and Corbacioglu, Selim

Published
2024
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2. Outcomes of HLA-mismatched HSCT with TCRαβ/CD19 depletion or post-HSCT cyclophosphamide for inborn errors of immunity

Author

Lum, Su Han, Albert, Michael H., Gilbert, Patrick, Sirait, Tiarlan, Algeri, Mattia, Muratori, Rafaella, Fournier, Benjamin, Laberko, Alexandra, Karakukcu, Musa, Unal, Elrem, Ayas, Mouhab, Yadav, Satya Prakash, Fisgin, Tunc, Elfeky, Reem, Fernandes, Juliana, Faraci, Maura, Cole, Theresa, Schulz, Ansgar, Meisel, Roland, Zecca, Marco, Ifversen, Marianne, Biffi, Alessandra, Diana, Jean-Sebastien, Vallée, Tanja, Giardino, Stefano, Ersoy, Gizem Zengin, Moshous, Despina, Gennery, Andrew R., Balashov, Dmitry, Bonfim, Carmem, Locatelli, Franco, Lankester, Arjan, Neven, Bénédicte, and Slatter, Mary

Published
2024
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4. Outcomes of hematopoietic stem cell transplantation in 813 pediatric patients with Fanconi anemia

Author

Lum, Su Han, Eikema, Dirk-Jan, Piepenbroek, Brian, Wynn, Robert F., Samarasinghe, Sujith, Dalissier, Arnaud, Kalwak, Krysztof, Ayas, Mouhab, Hamladji, Rose-Marie, Yesilipek, Akif, Dalle, Jean-Hugues, Uckan-Cetinkaya, Duygu, Bierings, Marc, Kupesiz, Alphan, Halahleh, Khalid, Skorobogatova, Elena, Öztürk, Gülyüz, Faraci, Maura, Renard, Cecile, Evans, Pamela, Corbacioglu, Selim, Locatelli, Franco, Dufour, Carlo, Risitano, Antonio, and Peffault de Latour, Régis

Published
2024
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5. Influence of invasive aspergillosis during acute leukaemia treatment on survival after allogeneic stem cell transplantation: a prospective study of the EBMT Infectious Diseases Working Party

Author

Penack, Olaf, Tridello, Gloria, Salmenniemi, Urpu, Martino, Rodrigo, Khanna, Nina, Perruccio, Katia, Fagioli, Franca, Richert-Przygonska, Monika, Labussière-Wallet, Hélène, Maertens, Johan, Jubert, Charlotte, Aljurf, Mahmoud, Pichler, Herbert, Kriván, Gergely, Kunadt, Desiree, Popova, Marina, Gabriel, Melissa, Calore, Elisabetta, Blau, Igor Wolfgang, Benedetti, Fabio, Itäla-Remes, Maija, de Kort, Elizabeth, Russo, Domenico, Faraci, Maura, Ménard, Anne-Lise, Borne, Peter von dem, Poiré, Xavier, Yesilipek, Akif, Gozdzik, Jolanta, Yeğin, Zeynep Arzu, Yañez, Lucrecia, Facchini, Luca, Van Gorkom, Gwendolyn, Thurner, Lorenz, Kocak, Ulker, Sampol, Antònia, Zuckerman, Tsila, Bierings, Marc, Mielke, Stephan, Ciceri, Fabio, Wendel, Lotus, Knelange, Nina, Mikulska, Malgorzata, Averbuch, Dina, Styczynski, Jan, Camara, Rafael de la, and Cesaro, Simone

Published
2024
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6. Haematopoietic stem cell transplantation after reduced intensity conditioning in children and adolescents with chronic myeloid leukaemia: A prospective multicentre trial of the I‐BFM Study Group

Author

Pichler, Herbert, primary, Sedlacek, Petr, additional, Meisel, Roland, additional, Beier, Rita, additional, Faraci, Maura, additional, Kalwak, Krzysztof, additional, Ifversen, Marianne, additional, Müller, Ingo, additional, Stein, Jerry, additional, Vettenranta, Kim, additional, Kropshofer, Gabriele, additional, Kolenova, Alexandra, additional, Karlhuber, Susanne, additional, Glogova, Evgenia, additional, Poetschger, Ulrike, additional, Peters, Christina, additional, Suttorp, Meinolf, additional, Matthes‐Leodolter, Susanne, additional, and Balduzzi, Adriana, additional

Published
2024
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7. Phase II Study of Allogeneic Hematopoietic Stem Cell Transplantation for Children with High-Risk Neuroblastoma Using a Reduced-Intensity Conditioning Regimen: Results from the AIEOP Trial

Author

Prete, Arcangelo, primary, Lanino, Edoardo, additional, Saglio, Francesco, additional, Biffi, Alessandra, additional, Calore, Elisabetta, additional, Faraci, Maura, additional, Rondelli, Roberto, additional, Favre, Claudio, additional, Zecca, Marco, additional, Casazza, Gabriella, additional, Porta, Fulvio, additional, Luksch, Roberto, additional, Cesaro, Simone, additional, Rabusin, Marco, additional, Parasole, Rosanna, additional, Mura, Rosa Maria, additional, Lo Nigro, Luca, additional, Leardini, Davide, additional, Pagliara, Daria, additional, Locatelli, Franco, additional, and Fagioli, Franca, additional

Published
2024
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8. Umbilical Cord Blood Transplantation for Fanconi Anemia With a Special Focus on Late Complications: a Study on Behalf of Eurocord and SAAWP-EBMT

Author

Rafii, Hanadi, primary, Volt, Fernanda, additional, Bierings, Marc, additional, Dalle, Jean-Hugues, additional, Ayas, Mouhab, additional, Rihani, Rawad, additional, Faraci, Maura, additional, de Simone, Giuseppina, additional, Sengeloev, Henrik, additional, Passweg, Jakob, additional, Cavazzana, Marina, additional, Costello, Regis, additional, Maertens, Johan, additional, Biffi, Alessandra, additional, Johansson, Jan-Erik, additional, Montoro, Juan, additional, Guepin, Gabrielle Roth, additional, Diaz, Miguel Angel, additional, Sirvent, Anne, additional, Kenzey, Chantal, additional, Rivera Franco, Monica M., additional, Cappelli, Barbara, additional, Scigliuolo, Graziana Maria, additional, Rocha, Vanderson, additional, Ruggeri, Annalisa, additional, Risitano, Antonio, additional, De Latour, Regis Peffault, additional, and Gluckman, Eliane, additional

Published
2024
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9. Long-Term Complications after Allogeneic Hematopoietic Stem Cell Transplantation with Treosulfan- or Busulfan-Based Conditioning in Pediatric Patients with Acute Leukemia or Myelodysplastic Syndrome: Results of an Associazione Italiana Ematologia Oncologia Pediatrica Retrospective Study

Author

Saglio, Francesco, Pagliara, Daria, Zecca, Marco, Balduzzi, Adriana, Cattoni, Alessandro, Prete, Arcangelo, Tambaro, Francesco Paolo, Faraci, Maura, Calore, Elisabetta, Locatelli, Franco, and Fagioli, Franca

Published
2024
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10. HLA‐haploidentical stem cell transplantation in children with inherited bone marrow failure syndromes: A retrospective analysis on behalf of EBMT severe aplastic Anemia and pediatric diseases working parties

Author

Giardino, Stefano, primary, Eikema, Dirk‐Jan, additional, Piepenbroek, Brian, additional, Algeri, Mattia, additional, Ayas, Mouhab, additional, Faraci, Maura, additional, Tbakhi, Abdelghani, additional, Zecca, Marco, additional, Essa, Mohammed, additional, Neven, Bénédicte, additional, Bertrand, Yves, additional, Kharya, Gaurav, additional, Bykova, Tatiana, additional, Lawson, Sarah, additional, Petrini, Mario, additional, Mohseny, Alexander, additional, Rialland, Fanny, additional, James, Beki, additional, Colita, Anca, additional, Fahd, Mony, additional, Cesaro, Simone, additional, Schulz, Ansgar, additional, Kleinschmidt, Katharina, additional, Kałwak, Krzysztof, additional, Corbacioglu, Selim, additional, Dufour, Carlo, additional, Risitano, Antonio, additional, and de Latour, Régis Peffault, additional

Published
2024
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11. An expert consensus on prevention, diagnosis and management of hemorrhagic cystitis in pediatric hematopoietic cell transplantation, on behalf of the Infectious Disease and Hematopoietic Cell Transplant Working groups of Italian Pediatric Hematology Oncolo-gy Association (AIEOP)

Author

Dell'Orso, Gianluca, primary, Carlucci, Marcello, additional, Cesaro, Simone, additional, Olcese, Evelina, additional, Balduzzi, Adriana, additional, Vendemini, Francesca, additional, Catti, Massimo, additional, Saglio, Francesco, additional, Compagno, Francesca, additional, Maximova, Natalia, additional, Rabusin, Marco, additional, Menconi, Maria Cristina, additional, Perruccio, Katia, additional, Soncini, Elena, additional, Tambaro, Francesco Paolo, additional, tintori, Veronica, additional, Pagliara, Daria, additional, and Faraci, Maura, additional

Published
2024
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12. Matched unrelated donor transplantation versus haploidentical transplantation with post-transplant cyclophosphamide in children with acute myeloid leukemia: a PDWP-EBMT study

Author

Ruggeri, Annalisa, primary, Santoro, Nicole, additional, Galimard, Jacques-Emmanuel, additional, Kalwak, Krzysztof, additional, Algeri, Mattia, additional, Zubarovskaya, Ludmila, additional, Czyzewski, Krzysztof, additional, Skorobogatova, Elena, additional, Sedlacek, Petr, additional, Besley, Caroline, additional, Balduzzi, Adriana, additional, Bertrand, Yves, additional, Peristeri, Julia, additional, Fagioli, Franca, additional, Ifversen, Mariane, additional, Gozdzik, Jolanta, additional, Peters, Christina, additional, Versluijs, Birgitta, additional, Biffi, Alessandra, additional, Prete, Arcangelo, additional, Faraci, Maura, additional, Ghemlas, Ibrahim, additional, Bodova, Ivana, additional, Aleinikova, Olga, additional, Dalissier, Arnaud, additional, Rocha, Vanderson, additional, and Corbacioglu, Selim, additional

Published
2024
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13. Interleukin-1 blockade in patients with Wiskott-Aldrich syndrome: a retrospective multinational case series

Author

Naviglio, Samuele, Cicalese, Maria Pia, Rivers, Elizabeth, Ferrua, Francesca, Bonfim, Carmem, Cenciarelli, Sabina, Cheong, Kai-Ning, Faraci, Maura, Giardino, Stefano, Ghosh, Sujal, Lee, Pamela P., Lyra, Paula Teixeira, Meisel, Roland, Sofia, Valentina, Tessitore, Antimo, Tommasini, Alberto, Valencic, Erica, Vallée, Tanja Christine, Volpi, Stefano, Worth, Austen J., Rabusin, Marco, Albert, Michael H., Thrasher, Adrian J., and Aiuti, Alessandro

Published
2024
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14. An expert consensus on prevention, diagnosis, and management of hemorrhagic cystitis in pediatric hematopoietic cell transplantation, on behalf of the Infectious Disease and Hematopoietic Cell Transplant Working groups of Italian Pediatric Hematology Oncology Association (AIEOP)

Author

Dell’Orso, Gianluca, Carlucci, Marcello, Cesaro, Simone, Olcese, Evelina, Balduzzi, Adriana, Vendemini, Francesca, Catti, Massimo, Saglio, Francesco, Compagno, Francesca, Maximova, Natalia, Rabusin, Marco, Menconi, Maria Cristina, Perruccio, Katia, Soncini, Elena, Tambaro, Francesco Paolo, Tintori, Veronica, Pagliara, Daria, and Faraci, Maura

Abstract

The optimal management of hemorrhagic cystitis (HC) in hematopoietic stem cell transplantation (HCT) is debated, both for early onset HC (EOHC) secondary to chemotherapy toxicity and BK Polyomavirus (BKPyV)-related HC, due to the lack of controlled trials, particularly referred to pediatric setting. Actually, clinical practice is mainly based on guidelines of the European Conference on Infections in Leukemia, 6thedition, which considers both adult and pediatric populations but concludes that, despite much progress in understanding the pathogenesis, epidemiology, and risk factors, this complication still represents a disabling unmet clinical need with limited prophylactic and therapeutic options. Additionally, the Guidelines of the American Society of Clinical Oncology define the management of chemotherapeutic toxicity independently from the patients’ population. A panel of experts belonging to the Hematopoietic Cell Transplant and Infectious Disease Working Group (WG) of Associazione Italiana di Emato-Oncologia Pediatrica (AIEOP) developed a consensus to define the best practices in prevention, diagnosis, and management of HC in pediatric HCT setting.

Published
2024
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15. Safety and efficacy of brincidofovir for Adenovirus infection in children receiving allogeneic stem cell transplantation: an AIEOP retrospective analyses

Author

Perruccio, Katia, Menconi, Mariacristina, Galaverna, Federica, Pagliara, Daria, Carraro, Francesca, Fagioli, Franca, Calore, Elisabetta, Biffi, Alessandra, Baretta, Valentina, Massei, Maria Speranza, Capolsini, Ilaria, Faraci, Maura, Verna, Marta, Soncini, Elena, Caniglia, Maurizio, Locatelli, Franco, and Cesaro, Simone

Published
2024
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16. Epilepsy after acute central nervous system complications of pediatric hematopoietic cell transplantation: A retrospective, multicenter study.

Author

Bergonzini L, Leardini D, Rao R, Foiadelli T, Faraci M, Mancardi MM, Nobile G, Orsini A, Savasta S, Gottardi F, Fetta A, Mina T, Casazza G, Menconi MC, Pruna D, Mura RM, Piroddi A, Rucci P, Masetti R, and Cordelli DM

Abstract

Background: Acute central nervous system (CNS) complications are common and well described among pediatric patients undergoing haematopoietic cell transplantation (HCT). However, their long-term outcomes are not known. The aim of this study is to describe the incidence, characteristics, and risk factors of long-term epilepsy in pediatric patients with acute CNS complications of HCT., Methods: This retrospective study included pediatric patients who developed acute CNS complications from autologous or allogeneic HCT between 2000 and 2022. Clinical, therapeutic and prognostic data including long-term outcomes were analyzed. A diagnosis of epilepsy was provided if unprovoked seizures occurred during follow-up., Results: Ninety-four patients (63 males, 31 females, median age 10 years, range 1-21 years) were included. The most common acute CNS complications were posterior reversible encephalopathy syndrome (n = 43, 46 %) and infections (n = 15, 16 %). Sixty-five patients (69 %) had acute symptomatic seizures, with 14 (16 %) having one or more episodes of status epilepticus (SE). Nine patients (9.6 %) were diagnosed with long-term focal epilepsy during the follow-up (5-year cumulative incidence from the acute complication, 13.3 %). Acute symptomatic SE during neurological complications of HCT was associated with an increased risk of long-term epilepsy (OR=14, 95 % CI 2.87-68.97)., Conclusions: A higher occurrence of epilepsy has been observed in our cohort compared to the general population. Acute symptomatic SE during HCT was associated with a higher risk of long-term epilepsy. Pediatric patients with CNS complications during HCT could benefit from specific neurological follow-up. Further studies are needed to characterize mechanisms of epileptogenesis in pediatric patients undergoing HCT., Competing Interests: Declaration of competing interest The Authors declare no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (Copyright © 2024 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.)

Published
2024
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17. An expert consensus on prevention, diagnosis, and management of hemorrhagic cystitis in pediatric hematopoietic cell transplantation, on behalf of the Infectious Disease and Hematopoietic Cell Transplant Working groups of Italian Pediatric Hematology Oncology Association (AIEOP).

Author

Dell'Orso G, Carlucci M, Cesaro S, Olcese E, Balduzzi A, Vendemini F, Catti M, Saglio F, Compagno F, Maximova N, Rabusin M, Menconi MC, Perruccio K, Soncini E, Tambaro FP, Tintori V, Pagliara D, and Faraci M

Abstract

The optimal management of hemorrhagic cystitis (HC) in hematopoietic stem cell transplantation (HCT) is debated, both for early onset HC (EOHC) secondary to chemotherapy toxicity and BK Polyomavirus (BKPyV)-related HC, due to the lack of controlled trials, particularly referred to pediatric setting. Actually, clinical practice is mainly based on guidelines of the European Conference on Infections in Leukemia, 6 th edition, which considers both adult and pediatric populations but concludes that, despite much progress in understanding the pathogenesis, epidemiology, and risk factors, this complication still represents a disabling unmet clinical need with limited prophylactic and therapeutic options. Additionally, the Guidelines of the American Society of Clinical Oncology define the management of chemotherapeutic toxicity independently from the patients' population. A panel of experts belonging to the Hematopoietic Cell Transplant and Infectious Disease Working Group (WG) of Associazione Italiana di Emato-Oncologia Pediatrica (AIEOP) developed a consensus to define the best practices in prevention, diagnosis, and management of HC in pediatric HCT setting., (© 2024. The Author(s), under exclusive licence to Springer Nature Limited.)

Published
2024
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