1. The role of histology on the outcome of sinonasal carcinomas treated with radiotherapy: a single institution experience.
- Author
-
Kazemian, Ali, Farazmand, Borna, Taherioun, Maryam, Razmkhah, Mahdie, Shirkhoda, Mohammad, Jalaeefar, Amirmohsen, Garajei, Ata, Jafari, Mehrdad, Heidari, Farrokh, Aghili, Mahdi, and Ghalehtaki, Reza
- Subjects
- *
ADENOID cystic carcinoma , *SQUAMOUS cell carcinoma , *PARANASAL sinuses , *OVERALL survival , *TREATMENT effectiveness - Abstract
Purpose: Sinonasal malignancies are a rare group of head and neck cancers. We aimed to report the oncological outcomes based on histological types in patients who underwent radiotherapy. Materials and Methods: In this single-institution study, we retrospectively retrieved and analyzed data of patients with sinonasal carcinomas who underwent radiotherapy during 2011-2016 as part of their treatment. The 3-year rate of local, regional, and distant recurrences, and overall survival were evaluated according to the histological type. Results: A total of 28 patients were evaluated in this study, the majority of whom were male (60%). Squamous cell carcinoma (SCC), adenoid cystic carcinoma (ACC), and adenocarcinoma (ADC) were found in 15 patients (53.5%), 8 (28.5%), and 5 (18%), respectively. The highest rates of local and regional recurrences were observed in ACC and SCC, respectively. Distant recurrences were numerically more common in ADC. The 3-year OS was 48%, 50%, and 73% in SCC, ADC, and ACC, respectively. Conclusion: Different histopathologies of sinonasal cancer seem to have different patterns of failure, and this may be considered in the treatment approach. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF