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The article in the Journal of Neurological Surgery. Part B. Skull Base, published on February 2, 2025, presents a 2-dimensional endoscopic video showcasing the successful resection of a retro-infundibular craniopharyngioma while preserving the pituitary stalk. The surgical approach involved removing the bony sellar face, tuberculum, and planum for enhanced visualization, followed by careful tumor removal behind the right side of the pituitary stalk to maintain normal pituitary gland function. The authors, Alexander F. Kuffer, Danielle Golub, Mark B. Chaskes, Judd H. Fastenberg, and Amir R. Dehdashti, reported on this procedure. [Extracted from the article]

This article discusses the use of endoscopic endonasal surgery (EES) as an alternative treatment for microprolactinomas, which are small pituitary tumors. The study, conducted at multiple medical centers in the United States and the Netherlands, found that EES had a surgical cure rate of nearly 70% for microprolactinomas. The main predictor of surgical success was achieving gross total resection of the tumor, with minimal complications reported. The study highlights the potential of EES as a viable option for patients who are unable to tolerate long-term dopamine agonist therapy for microprolactinomas. [Extracted from the article]

Simple Summary: Squamous cell carcinoma (SCC) is the most common cancer affecting the sinonasal tract. Unfortunately, it has a high rate of recurrence, affecting nearly half of patients who are initially treated. Nonetheless, there are limited guidelines for diagnosing and managing recurrent disease. This review discusses diagnosis, prognostic factors, and available treatment algorithms for recurrent cases. For eligible patients, surgery remains the most effective long-term treatment. When surgery is not an option, chemotherapy and radiation are used either to help control the disease or to ease symptoms. Newer treatments, such as immunotherapy and advanced radiation techniques, are being actively researched as promising alternatives. Squamous cell carcinoma is the most common malignancy affecting the sinonasal tract. Local recurrence is the main pattern of treatment failure, affecting nearly half of patients treated for primary sinonasal squamous cell carcinoma (SNSCC). Due to disease rarity and heterogeneity of practices, there are limited guidelines for how to diagnose and care for these patients. This paper reviews current evidence regarding etiology, pathophysiology, diagnosis, prognostic factors, and treatment modalities of recurrent SNSCC (rSNSCC). Currently, salvage surgery offers the only durable approach for eligible patients. These resections often require robust reconstructive options due to prior surgery or radiation. Chemoradiation is offered as an adjuvant or palliative approach when surgery is not a feasible option. Emerging options such as immunotherapy and particle therapy remain an area of ongoing investigation. [ABSTRACT FROM AUTHOR]