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Your search keyword '"Kemmling Y"' showing total 3 results
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3 results on '"Kemmling Y"'

1. Compositional clusters in the nasal microbiome as predictors of SARS-CoV-2 infection - results from the German National Cohort (NAKO) study

Author

Kleine Bardenhorst, S, Six-Merker, J, Peters, A, Krist, L, Keil, T, Nimptsch, K, Pischon, T, Gastell, S, Schulze, MB, Wolters, M, Günther, K, Schikowski, T, Schmidt, B, Stang, A, Michels, KB, Klee, B, Mikolajczyk, R, Harth, V, Obi, N, Lange, B, Klett-Tammen, CJ, Lieb, W, Becher, H, Kaaks, R, Karch, A, Berger, K, Nauck, M, Khattak M, N, Baurecht, H, Leitzmann, M, Holleczek, B, Brenner, H, Kemmling, Y, Panreck, L, Vital, M, Rübsamen, N, Kleine Bardenhorst, S, Six-Merker, J, Peters, A, Krist, L, Keil, T, Nimptsch, K, Pischon, T, Gastell, S, Schulze, MB, Wolters, M, Günther, K, Schikowski, T, Schmidt, B, Stang, A, Michels, KB, Klee, B, Mikolajczyk, R, Harth, V, Obi, N, Lange, B, Klett-Tammen, CJ, Lieb, W, Becher, H, Kaaks, R, Karch, A, Berger, K, Nauck, M, Khattak M, N, Baurecht, H, Leitzmann, M, Holleczek, B, Brenner, H, Kemmling, Y, Panreck, L, Vital, M, and Rübsamen, N

Published
2024

3. The RESIST Senior Individuals Cohort: Design, participant characteristics and aims.

Author

Roesner LM, Gupta MK, Kopfnagel V, van Unen N, Kemmling Y, Heise JK, Castell S, Jiang X, Riemann L, Traidl S, Lange B, Sühs KW, Illig T, Strowig T, Li Y, Förster R, Huehn J, Schulz TF, and Werfel T

Abstract

The number of older adults worldwide is growing exponentially. However, while living longer, older individuals are more susceptible to both non-infectious and infectious diseases, at least in part due to alterations of the immune system. Here, we report on a prospective cohort study investigating the influence of age on immune responses and susceptibility to infection. The RESIST Senior Individuals (SI) cohort was established as a general population cohort with a focus on the elderly, enrolling an age- and sex-stratified sample of 650 individuals (n = 100 20-39y, n = 550 61-94y, 2019-2023, Hannover, Germany). It includes clinical, demographic, and lifestyle data and also extensive biomaterial sampling. Initial insights indicate that the SI cohort exhibits characteristics of the aging immune system and the associated susceptibility to infection, thereby providing a suitable platform for the decoding of age-related alterations of the immune system and unraveling the molecular mechanisms underlying the impaired immune responsiveness in aging populations by exploring comprehensive, unbiased multi-omics datasets., (© 2024. The Author(s).)

Published
2024
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