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To improve longevity and performance of dental implants by reducing stress-shielding, a modification of the internal structure of the implant can be a solution. In this paper the inner design of the implant is generated either using a topology optimization approach or an approach based on TPMS lattice structures. These approaches aim to maintain long-term stability and to reduce stress-shielding. For both approaches, the mechanostat model was applied to investigate the influence of the inner structure to the surrounding bone tissue and compare the standard uniform implant. For the investigation an ANSYS model was used with material parameters obtained from a mechanical test of additively manufactured Ti6Al4V. Compared to the uniform implant, the topology-optimized implant showed 20% less stress-shielding, and the implant with triply periodic minimal surface structures (TPMS) showed 15% less stress-shielding. Further, the long-term-stability was investigated by introducing a high-cycle fatigue material model. Despite a change in the internal structure and a 45% reduction in the mass of the topology-optimized implant, the cycle numbers specified in the DIN EN ISO 14801 standard were fulfilled., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved.)