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Despite classical conceptions of schizophrenia as a progressive illness with a high chronification, current long-term follow-up studies show a higher proportion of remission, possibly also a higher proportion of recovery than previously assumed. The heterogeneity of clinical courses is also reflected in different trajectories of cognitive and biological (e.g., imaging) variables, in which many of those affected show remission. Early clinical intervention during the first weeks and months following the onset of psychosis are decisive not only for early remission but also possibly for the long-term outcome. The treatment and reduction of somatic comorbidities are promising approaches in addition to a differentiated core treatment to positively influence the course of the illness even years after the disease. The identification of additional predictors, e.g., based on biological parameters, can together with machine learning approaches contribute to optimization of an individualized core treatment. [ABSTRACT FROM AUTHOR]

The forum of psychoanalysis deals with the concept of countertransference and its development. The author Ursula Kreuzer-Haustein examines the use of the term and emphasizes the importance of unconsciousness in countertransference. She discusses Freud's receiver model and the role of the preconscious in the conceptualization of countertransference. The author warns against neglecting unconsciousness and emphasizes the creative dynamics of the preconscious in psychoanalytic work. [Extracted from the article]

TV news programmes use social media intensively to promote and distribute their content. Instagram has become integral in this field, as all major players have their own account and Instagram has become a widely used news source. This article analyzes the news coverage of TV news shows on Instagram as a designed space, asking which genres are used, how they are positioned in regard to the technical and social affordances of the platform, and what implications their form and style have for journalism culture(s). Underpinned by the concepts of platformization, digital mediality, and media affordances, the analysis will focus on the characteristic stylistic forms of Instagram news coverage, comparing the Instagram accounts of six German speaking private and public TV news stations from Switzerland, Germany, and Austria. The corpus includes 100 posts and reels from each account collected in September 2023. The analysis identifies different genre profiles of the accounts and then focuses on the question of how different common genres (like headlines, newsbites, news briefs, and reports) as well as reels are designed multimodally, including different structural parts and their patterned style. [ABSTRACT FROM AUTHOR]

Copyright of Die MKG-Chirurgie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of HMD: Praxis der Wirtschaftsinformatik is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of HMD: Praxis der Wirtschaftsinformatik is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Forensische Psychiatrie, Psychologie, Kriminologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Forensische Psychiatrie, Psychologie, Kriminologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objectives: The research objectives were to identify and synthesise prevailing definitions and indices of resilience in maternal, newborn, and child health (MNCH) and propose a harmonised definition of resilience in MNCH research and health programmes in low- and middle-income countries (LMICs). Design: Scoping review using Arksey and O'Malley's framework and a Delphi survey for consensus building. Participants: Mothers, new-borns, and children living in low- and middle-income countries were selected as participants. Outcomes: Resilience as defined by the authors was deduced from the studies. Results: Twenty-two out of 76,566 cited studies published between 2006 and 2010 were included in the review. Thirteen (59.1%) examined maternal resilience, and nine (40.9%) examined newborn and child health resilience; most of the included studies were quantitative (n = 17; 81%). Seven studies defined 'resilience' in the context of maternal health, most of which described the term at the individual level. 'Maternal resilience' was measured using validated scales in five studies; another five defined newborn and child resilience. Only one reviewed study used maternal characteristics to identify newborn and child resilience. The synthesised consensus definition of 'maternal, newborn, and child resilience' is 'A woman's ability to prevent or adapt to significant and challenging circumstances including threats, tragedy, and trauma to herself during pregnancy, childbirth, and puerperium and to her neonates or children five years or younger'. Conclusion: The information identified was limited but included a few definitions of resilience in MNCH and an index of child resilience in LMICs. The proposed definition is useful for MNCH programme implementation and interventions in LMICs. Scoping review registration: The protocol for this review was registered in the open science framework at the registered address (https://osf.io/jt6nr). Plain Language Summary: We used a robust search strategy to conduct a scoping review that generated a large amount of literature which we then pruned using a high-performing machine learning algorithm. The study used a novel method to generate and propose a new and uniform definition for resilience in maternal, newborn and child health programmes and research. One important limitation is that this study is a scoping review and did not assess the quality of the studies included in the review. Another limitation is that the definitions were generated from the studies and reports we identified and may have inadvertently missed some publications that are related to our topic because they were not in the databases searched. [ABSTRACT FROM AUTHOR]

Copyright of Zeitschrift für Angewandte Linguistik is the property of De Gruyter and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Zusammenfassung: Atopische Dermatitis (AD) ist eine weit verbreitete entzündliche Hauterkrankung, die durch chronische Entzündung, eine gestörte Hautbarriere und mikrobielle Dysbiose gekennzeichnet ist, wobei Staphylococcus aureus eine wichtige Rolle in der Pathogenese spielt. Diese Übersichtsarbeit untersucht die Stammvielfalt und Mikroevolution von S. aureus bei AD-Patienten und zeigt, wie sich bestimmte Stämme an das veränderte Hautmilieu anpassen und die Erkrankung verschlimmern. Die Übersichtsarbeit unterstreicht die Bedeutung der Variation spezifischer funktioneller Gene bei S. aureus-Stämmen, die ihre Fähigkeit zur Anpassung an unterschiedliche Mikroumgebungen verbessert und ihr pathogenes Potenzial prägt. Darüber hinaus wird diskutiert, wie mobile genetische Elemente, insbesondere Prophagen, zur genetischen Diversität beitragen und die Virulenz und Antibiotikaresistenz von S. aureus bei AD fördern. Die klinischen Herausforderungen, die diese stammspezifischen Faktoren für die Behandlung der Krankheit darstellen, werden hervorgehoben. Die Arbeit plädiert für die Integration fortgeschrittener Genomikinstrumente wie vollständige Genomsequenzierung und maschinelles Lernen, um zielgerichtete Therapien zu entwickeln. Durch die Fokussierung auf die genetische Anpassungsfähigkeit von S. aureus und ihre Auswirkungen auf die AD unterstreicht diese Übersichtsarbeit den Bedarf an stammspezifischer Diagnostik und personalisierten Behandlungsstrategien, um die Ergebnisse für die Patienten zu verbessern. [ABSTRACT FROM AUTHOR]

Zusammenfassung: Es gibt keine ausreichende Evidenz für die Wirksamkeit von Januskinase-Inhibitoren (JAKi), einer Klasse gezielter synthetischer krankheitsmodifizierender Antirheumatika (tsDMARD), bei der Behandlung der interstitiellen Lungenerkrankung (ILD), die mit rheumatoider Arthritis (RA) assoziiert ist. Hier stellen wir einen Fall von RA-ILD vor, der gegenüber früheren Behandlungen refraktär war und ein günstiges Ansprechen auf Upadacitinib zeigte. Ein 69-jähriger Mann, ehemaliger Raucher, wurde mit RA-ILD diagnostiziert, basierend auf einer persistierenden symmetrischen Polyarthritis, erhöhten CRP-Spiegeln (C-reaktives Protein) und Erythrozyten-Sedimentationsraten, einer verminderten Diffusionskapazität für Kohlenmonoxid/vermindertes Alveolarvolumen (DLCO 69,9%) und einer bilateralen Milchglastrübung mit Traktionsbronchiektasie, vorwiegend im unteren Lungenlappen. Es wurde eine initiale Behandlung mit oralem Prednisolon und Methotrexat begonnen; der Patient zeigte jedoch eine Verschlechterung der Dyspnoe, Anomalien in der hochauflösenden Computertomografie des Brustraums und eine verminderte Lungenfunktion. Die Prednisolon-Dosis wurde erhöht und Methotrexat zugunsten von Tacrolimus ersetzt; Tacrolimus wurde jedoch schließlich aufgrund einer Nierenfunktionsstörung abgesetzt. Nachfolgende Behandlungsänderungen beinhalteten Abatacept gefolgt von intravenösem Cyclophosphamid, doch die ILD-Aktivität verschlechterte sich weiter und erfüllte die Kriterien einer progressiven Lungenfibrose. Etwa 4,5 Jahre nach der RA-Diagnose verbesserten sich die Dyspnoe, die radiologischen Anomalien und die DLCO nach Umstellung der Behandlung auf Upadacitinib, einer der JAKi. Die JAKi-Therapie kann als Behandlungsoption für refraktäre RA-ILD infrage kommen. [ABSTRACT FROM AUTHOR]

Copyright of Lernen und Lernstörungen is the property of Hogrefe AG and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Zeitschrift für Pädagogik is the property of Julius Beltz GmbH & Co. KG Beltz Juventa and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Zeitschrift für Pädagogische Psychologie is the property of Hogrefe AG and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)