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This article explores the importance of addressing the drug overdose epidemic through policy interventions. It identifies three main strategies: overdose education and naloxone distribution, harm reduction, and peer support programs. The focus is on harm reduction, specifically removing barriers to syringe service programs. The article includes an interview with Madeleine Lepore, a psychiatric nurse practitioner who is passionate about harm reduction and has been volunteering in a syringe service program. The author also discusses their own research on harm reduction policies, with a focus on syringe decriminalization and the need for syringe service programs in rural communities in Pennsylvania. They emphasize the effectiveness and cost-effectiveness of harm reduction, while acknowledging the existing stigma. The article highlights progress made in Pennsylvania, such as the decriminalization of fentanyl test strips and proposed bills for syringe service programs. It emphasizes the importance of harm reduction in addressing the opioid epidemic and intimate partner violence, and discusses the author's role in nursing education and teaching students about addiction nursing and harm reduction. [Extracted from the article]