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Edentulism is a prevalent oral health issue that has a detrimental social and psychological impact on patients ‘quality of life. The treatment option adopted has a significant impact on the level of quality with the goal can be achieved. For edentulous patients, implant-supported fixed restorations are a well-established treatment modality. Implant dentistry philosophies and procedures have evolved and changed over the time to give esthetics and functional outcomes. Immediate loading has various advantages over traditional loading without sacrificing the quality of the output. An immediate fixed provisional promotes a high level of patient satisfaction with respect to esthetics, phonetics, mastication and psychological comfort, enabling patients to return to their normal routine and maintain quality of life within a short period of time. Without question, the optimal solution for any edentulous patient from whom it is still clinically viable to place implants is all-on-X dental implant solution. Whether All-on-four All-on-five, All-on-six or any variation of a full implant supported design, there is a best option for quality of life, long term durability, bone maintenance, health improvement and frankly happiness.

Cystic fibrosis (CF) is primarily known for its pulmonary consequences, which are extensively explored in the existing literature. However, it is noteworthy that individuals with CF commonly display gastrointestinal (G-I) manifestations due to the substantial presence of the cystic fibrosis transmembrane conductance regulator (CFTR) protein in the intestinal tract. Recognized as pivotal nonpulmonary aspects of CF, G-I manifestations exhibit a diverse spectrum. Identifying and effectively managing these manifestations are crucial for sustaining health and influencing the overall quality of life for CF patients. This review aims to synthesize existing knowledge, providing a comprehensive overview of the G-I manifestations associated with CF. Each specific G-I manifestation, along with the diagnostic methodologies and therapeutic approaches, is delineated, encompassing the impact of innovative treatments targeting the fundamental effects of CF on the G-I tract. The findings underscore the imperative for prompt diagnosis and meticulous management of G-I manifestations, necessitating a multidisciplinary team approach for optimal care and enhancement of the quality of life for affected individuals. In conclusion, the authors emphasize the urgency for further clinical studies to establish a more robust evidence base for managing G-I symptoms within the context of this chronic disease. Such endeavors are deemed essential for advancing understanding and refining the clinical care of CF patients with G-I manifestations.