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Background: The majority of primary, intraocular tumors in cats originate from the uvea and include feline diffuse iris melanoma, lymphoma, and iridociliary epithelial adenoma or adenocarcinoma. In this case report, we describe for the first time the clinical, histological, and immunohistochemical findings of a rare myxoid intraocular neoplasm arising from the ciliary body in a cat. Case presentation: A 14-year-old, female, spayed domestic shorthaired cat was presented for evaluation of discolouration of the right eye. Upon examination, a clear to light whitish-tan, bubble-shaped intraocular mass adherent to the inferior ciliary body and extending into the anterior chamber was noted. Within five weeks, the tumor was significantly larger and the eye had developed secondary glaucoma so was enucleated. Light microscopic examination of the globe revealed a multinodular, hypocellular neoplasm arising from the ciliary body composed of interwoven spindle cells embedded in abundant amounts of a lightly basophilic myxoid matrix. Neoplastic cells exhibited strong immunoreactivity for cytokeratin while also showing moderate to strong immunoreactivity to vimentin. A diagnosis was therefore made of an unusual intraocular myxoid epithelioid sarcoma arising from the ciliary body. Conclusions: Although apparently exceedingly rare, epithelioid myxosarcoma should be included as a differential diagnosis for intraocular tumors in cats and they represent a clinical, histologic, and immunohistochemical diagnostic challenge. Early surgical intervention should be considered to prevent local invasion and ascension to the brain. [ABSTRACT FROM AUTHOR]

Objective: Feline herpesvirus 1 (FHV‐1) causes ocular surface disease in domestic cats. The purpose of this study was to assess the relationship between bacterial ocular surface microbiota and outcomes for cats with FHV‐1 ocular surface disease. Animals Studied: Twenty‐two shelter‐housed cats with confirmed FHV‐1 ocular surface disease. Procedures: Animals were grouped according to FHV‐1 shedding and ocular clinical scores following intervention: worsened outcome (WorOut, n = 11) or improved outcome (ImpOut, n = 11). Scoring and conjunctival sampling were completed on Days 1 and 8 of twice daily antiviral treatment. Bacterial DNA was extracted and submitted for 16S rRNA gene sequencing. Real‐time polymerase chain reaction was performed for selected bacterial species. Overall DNA concentration between groups was assessed. Results: Bacterial microbiota relative abundance composition was significantly different between ImpOut and WorOut groups (weighted UniFrac p =.006). Alpha diversity was significantly higher in the ImpOut group compared with the WorOut group (Shannon p =.042, Simpson's p =.022, Pielou's p =.037). Differences in the relative abundance of various phyla and species were detected between groups. Total DNA concentration was higher in the WorOut group compared with the ImpOut group (p =.04). Feline GAPDH (p =.001) and Bilophila wadsworthia (p =.024) copy number was significantly higher in the ImpOut group compared with the WorOut group. Conclusions: The results highlight the important relationship between the bacterial ocular surface microbiota and FHV‐1 infection outcomes in cats treated with antiviral medications. Low bacterial species diversity, higher overall DNA (presumed predominantly bacterial) load, and certain bacterial phyla/species were associated with poor outcomes for cats with FHV‐1 ocular disease. [ABSTRACT FROM AUTHOR]

This article discusses a case of orbital emphysema in a 5-year-old shih tzu dog following enucleation surgery. Orbital emphysema is a rare complication that occurs when air accumulates in the orbit due to the retention of conjunctiva within the orbit. The condition is more commonly seen in brachycephalic breeds. The diagnosis was confirmed through fine-needle aspiration and cranial imaging. Treatment involved surgical exploration and ligation of the nasolacrimal duct. The dog recovered well with no complications or recurrence. It is important to completely remove all epithelial tissues during enucleation surgery to prevent complications such as orbital emphysema. [Extracted from the article]