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Your search keyword '"Liu, XiaoJun"' showing total 402 results
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402 results on '"Liu, XiaoJun"'

1. Attosecond pulse synthesis from high-order harmonic generation in intense squeezed light

Author

Wang, ShiJun, Lai, XuanYang, and Liu, XiaoJun

Subjects
Physics - Optics, Physics - Atomic Physics
Abstract

High-order harmonic generation (HHG) provides a broad spectral bandwidth for synthesizing attosecond pulses. However, in the current HHG schemes, only part of the harmonics can be phase-locked, which limits the ability to achieve shorter attosecond pulses. Here, we study attosecond pulse synthesis from HHG of an atom driven by an intense quantum light, i.e., squeezed light. It is interestingly found that the harmonics in the whole spectrum can be phase-locked and, by using these harmonics, the width of the synthesized attosecond pulse is greatly reduced. By developing strong-field approximation theory in squeezed light, the physics of the phase-locked harmonic generation throughout the HHG spectrum is revealed and is found to be independent of the target system. Furthermore, we uncover the dependence of the synthesized attosecond pulse width on the squeezing parameter of the squeezed light. Our findings provide a robust tool for obtaining phase-locked harmonics throughout the HHG spectrum for synthesizing short attosecond pulses., Comment: 6 pages, 4 figures

Published
2024

2. SparseAD: Sparse Query-Centric Paradigm for Efficient End-to-End Autonomous Driving

Author

Zhang, Diankun, Wang, Guoan, Zhu, Runwen, Zhao, Jianbo, Chen, Xiwu, Zhang, Siyu, Gong, Jiahao, Zhou, Qibin, Zhang, Wenyuan, Wang, Ningzi, Tan, Feiyang, Zhou, Hangning, Xu, Ziyao, Yao, Haotian, Zhang, Chi, Liu, Xiaojun, Di, Xiaoguang, and Li, Bin

Subjects
Computer Science - Computer Vision and Pattern Recognition
Abstract

End-to-End paradigms use a unified framework to implement multi-tasks in an autonomous driving system. Despite simplicity and clarity, the performance of end-to-end autonomous driving methods on sub-tasks is still far behind the single-task methods. Meanwhile, the widely used dense BEV features in previous end-to-end methods make it costly to extend to more modalities or tasks. In this paper, we propose a Sparse query-centric paradigm for end-to-end Autonomous Driving (SparseAD), where the sparse queries completely represent the whole driving scenario across space, time and tasks without any dense BEV representation. Concretely, we design a unified sparse architecture for perception tasks including detection, tracking, and online mapping. Moreover, we revisit motion prediction and planning, and devise a more justifiable motion planner framework. On the challenging nuScenes dataset, SparseAD achieves SOTA full-task performance among end-to-end methods and significantly narrows the performance gap between end-to-end paradigms and single-task methods. Codes will be released soon.

Published
2024

3. Table-Top Tunable Chiral Photonic Emitter

Author

Wang, Lu, Ciappina, Marcelo Fabián, Brabec, Thomas, and Liu, Xiaojun

Subjects
Physics - Optics
Abstract

The increasing interest in chiral light stems from its spiral trajectory along the propagation direction, facilitating the interaction between different polarization states of light and matter. Despite tremendous achievements in chiral light-related research, the generation and control of chiral pulse have presented enduring challenges, especially at the terahertz and ultraviolet spectral ranges, due to the lack of suitable optical elements for effective pulse manipulation. Conventionally, chiral light can be obtained from intricate optical systems, by an external magnetic field, or by metamaterials, which necessitate sophisticated optical configurations. Here, we propose a versatile tunable chiral emitter, composed of only two planar Weyl semimetals slabs, addressing the challenges in both spectral ranges. Our results open the way to a compact tunable chiral emitter platform in both terahertz and ultra-violet frequency ranges. This advancement holds the potential to serve as the cornerstone for integrated chiral photonics.

Published
2024

8. Galectin-3 predicts acute GvHD and overall mortality post reduced intensity allo-HCT: a BMT-CTN biorepository study

Author

McCarthy, Philip L., Attwood, Kristopher M., Liu, Xiaojun, Chen, George L., Minderman, Hans, Alousi, Amin, Bashey, Asad, Lowsky, Robert, Miklos, David B., Hansen, John, Westervelt, Peter, Yanik, Gregory, Waller, Edmund K., Howard, Alan, Blazar, Bruce R., Wallace, Paul K., Reshef, Ran, Horowitz, Mary M., Maziarz, Richard T., Levine, John E., and Mohammadpour, Hemn

Published
2024
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13. Digital Twin-driven Dynamic Scheduling Cloud Platform for Disassembly Workshop

Author

Jiao, Jie, Yuan, Gang, Liu, Xiaojun, Tian, Guangdong, Pham, Duc Truong, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Haddar, Mohamed, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Kwon, Young W., Editorial Board Member, Tolio, Tullio A. M., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Schmitt, Robert, Editorial Board Member, Xu, Jinyang, Editorial Board Member, Fera, Marcello, editor, Caterino, Mario, editor, Macchiaroli, Roberto, editor, and Pham, Duc Truong, editor

Published
2024
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21. Nutlin-3a regulates mouse adipose function by inhibition of CIDEC expression

Author

CHEN Enhui, YANG Jiahui, ZHAO Wei, XIE Xianghong, GUO Yanfang, LIU Xiaojun, YAN Li

Subjects
nutlin-3a, fat metabolism, adipose tissue, cidec, Medicine
Abstract

Objective To investigate the effect of Nutlin-3a, a mouse double minute 2 homolog (MDM2) inhibitor, on lipid metabolism of mouse adipose. Methods High-fat diet-induced obesity (DIO) C57BL/6J mice were randomly divided into a control group injected with DMSO and an experimental group injected with Nutlin-3a. Then we conducted glucose tolerance (GTT) and insulin tolerance (ITT) tests. The epididymal white adipose tissue (eWAT), inguinal white adipose tissue (iWAT) and brown adipose tissue (BAT) of animals were isolated and microscopy of WATs with hematoxylin-eosin (HE) staining was performed to observe the morphological changes of adipocytes. The expression of lipid metabolism related gene cell death-inducing DFF45-like effector C (CIDEC) in eWAT were detected by qPCR and Western blot. Results Compared with the control group, Nutlin-3a was found to promote the body weight (P＜0.001),but no effect on glucose tolerance and insulin sensitivity in DIO mice. Nutlin-3a treatment decreased the size of adipocytes and fat deposition in adipose tissue and downregulated the mRNA and protein levels of CIDEC in eWAT. Conclusions Nutlin-3a inhibits the formation of lipid droplets by downregulating expression of CIDEC in white adipose tissue.

Published
2024
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22. Sestrin1 is involved in the regulation of gluconeogenesis in mouse liver cells

Author

GUO Yanfang, GENG Chao, XIE Xianghong, CHEN Enhui, GUO Zeyu, ZHANG Minglong, LIU Xiaojun

Subjects
hepatic gluconeogenesis, stress-inducing protein 1(sesn1), sirtuin 1(sirt1), peroxisome proliferators-activated receptors gamma co-activator 1α(pgc-1α), Medicine
Abstract

Objective To investigate the role and regulatory mechanism of stress-inducing protein 1(SESN1) in liver gluconeogenesis of fasting mice. Methods RT-qPCR was used to detect mRNA expression of SESN1 in liver tissues of C57BL/6J mice and primary mouse hepatocytes treated with forskolin (Fsk) and dexamethasone(Dex). HepG2 cells were transfected with plasmids and the effects of SESN1 overexpression on mRNA expression of gluconeogenesis related genes PGC-1α, PEPCK and G6Pase was detected by RT-qPCR. The effect of SESN1 on the promoter activity of PGC-1α in HepG2 cells was studied using a dual luciferase reporter system. The effect of SESN1 on PGC-1α deacetylation was detected by overexpression of SESN1 and inhibition of SIRT1 expression.By knocking down SIRT1 expression, we detected whether it mediated the changes in mRNA levels of SESN1 induced gluconeogenesis related genes. Results The mRNA expression of SESN1 was significantly increased in liver tissues of starved C57BL/6J mice and in primary hepatocytes treated with Fsk and Dex(P＜0.001). Over-expression of SESN1 in HepG2 cells promoted mRNA expression of PGC-1α, PEPCK and G6Pase(P＜0.001) and promoter activity of PGC-1α(P＜0.001). Over-expression of SESN1 decreased the acetylation level of PGC-1α in primary hepatocytes.Sirt family inhibitors NAM and shRNA adenovirus interfered with SIRT1 expression respectively, and antagonized the deacetylation effect of SESN1 on PGC-1α. The expression of PGC-1α, PEPCK and G6Pase induced by SIRT1 was also significantly impaired(P＜0.000 1). Conclusions SESN1 regulates liver gluconeogenesis in mice with a SIRT1-dependent mechanism.

Published
2024
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