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Intestinal stem cells and Paneth cells interact with each other to maintain intestinal homeostasis and function, the interaction between intestinal stem cells and Paneth cells is regulated by mitochondria-related functions and energy conversion. The unique advantages of traditional Chinese medicine (TCM) in the treatment of intestinal diseases are also reflected in its effects on mitochondria and energy metabolism. This paper explores the influence of mitochondrial function and energy metabolism on the interaction between intestinal stem cells and Paneth cells, as well as the possible targets related to mitochondria in the treatment of intestinal diseases by TCM, summarizes the regulatory effects of TCM on mitochondria and energy metabolism, thereby restoring intestinal homeostasis and alleviating disease, with an aim to provide reference and theoretical basis for the research related to the TCM treatment of intestinal stem cells and Paneth cells based on mitochondria.

Patients with motor impairments (e.g., stroke, bone fracture, Parkinson's) are sensitive to the wearing experience of rehabilitation devices, and they often have difficulty accurately positioning them at an accurate position. While solutions involving optical systems or IMUs could potentially help alleviate the issue, they often introduce other challenges such as privacy concerns or discomforting experiences. With the emergence of wearable soft sensors during the last few decades, researchers widely apply soft sensors in rehabilitation to improve the wearing experience. However, these approaches have primarily focused on analyzing the sensor readings to improve accuracy rather than addressing the needs of patients and healthcare providers, and there is a lack of comprehensive design investigation and need assessment based on soft sensor-based rehabilitation systems for motor-impaired patients and their doctors. In this study, we developed an application, RehabFAB, utilizing fabric sensors for rehabilitation purposes. Besides, we evaluated our application and device and investigated the needs of patients and doctors for potential home rehabilitation applications. The investigation was conducted through thematic analysis, correlation analysis and System Usability Scale. The experimental results validated the efficacy, reliability and usability of our approach, with a SUS score of 81.75. In addition, the RehabFAB meets the expectations of motor-impaired patients and medical professionals as a home rehabilitation tool. Our core contributions lie in a thorough evaluation of the needs of motor-impaired patients in order to design a stable and reliable motion-tracking device based on soft sensors for their recovery. [ABSTRACT FROM AUTHOR]