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Your search keyword '"Mansur, Ameer"' showing total 4 results
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4 results on '"Mansur, Ameer"'

1. Evaluating the immunologically “cold” tumor microenvironment after treatment with immune checkpoint inhibitors utilizing PET imaging of CD4 + and CD8 + T cells in breast cancer mouse models

Author

Lu, Yun, Houson, Hailey A., Gallegos, Carlos A., Mascioni, Alessandro, Jia, Fang, Aivazian, Argin, Song, Patrick N., Lynch, Shannon E., Napier, Tiara S., Mansur, Ameer, Larimer, Benjamin M., Lapi, Suzanne E., Hanker, Ariella B., and Sorace, Anna G.

Published
2024
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4. Human Epidermal Growth Factor Receptor 2/Human Epidermal Growth Factor Receptor 3 PET Imaging

Author

Ducharme, Maxwell, Mansur, Ameer, Sligh, Luke, Ulaner, Gary A., Lapi, Suzanne E., and Sorace, Anna G.

Abstract

Human epidermal growth factor receptor 2 (HER2) and HER3 provide actionable targets for both therapy and imaging in breast cancer. Further, clinical trials have shown the prognostic impact of receptor status discordance in breast cancer. Intra- and intertumoral heterogeneity of both HER and hormone receptor expression contributes to inherent errors in tissue sampling, and single biopsies are incapable of identifying discordance in biomarker expression. Numerous PET radiopharmaceuticals have been developed to evaluate (or target for therapy) HER2 and HER3 expression. This review seeks to inform on challenges and opportunities in HER2 and HER3 PET imaging in both clinical and preclinical settings.

Published
2024
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