1. Porto-sinusoidal vascular disorder in chronic HBV: A significant coexistence not to be overlooked
- Author
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Pol Olivas, Valeria Perez-Campuzano, Lara Orts, Carla Montironi, Marta Magaz, Pablo Ruiz, Sarah Shalaby, Asunción Ojeda, Pau Rosich, Anna Baiges, Fanny Turon, Sabela Lens, Juan Carlos García Pagán, and Virginia Hernández-Gea
- Subjects
Porto-Sinusoidal Vascular Disease ,Non-cirrhotic Portal Hypertension ,Vascular liver diseases ,Idiopathic portal hypertension ,Chronic Hepatitis B ,Obliterative portal venopathy ,Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Background & Aims: Porto-sinusoidal vascular disorder (PSVD) encompasses a group of liver diseases with vascular abnormalities that can cause portal hypertension in the absence of cirrhosis. The new diagnostic criteria allow for coexistence with other liver diseases, however its relationship with chronic hepatitis B (CHB) remains unclear. This study aimed to assess HBV prevalence in a PSVD cohort and evaluate its clinical impact. Methods: This retrospective study was conducted on patients with PSVD at Hospital Clínic Barcelona. HBV serology was evaluated, and patients were categorized into HBV chronic infection, past infection, or no HBV exposure. Clinical characteristics and outcomes were compared. Results: We included 155 patients with PSVD. Prevalence of CHB and past HBV infection in patients with PSVD was higher than in the general population (5.8% vs. 0.5%, p
- Published
- 2024
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