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Corynebacterium striatum occasionally causes nosocomial infections, such as catheter-related bloodstream infection and pneumonia; however, C. striatum- related infective endocarditis or septic arthritis is uncommon. We present the case of an 85-year-old woman with infective endocarditis at the native valve and septic arthritis at the native shoulder joint caused by C. striatum. The patient was admitted for a 10-day history of fever and right shoulder pain. She had no history of artificial device implantation, injury, arthrocentesis, or hospitalization. A physical examination revealed conjunctival petechiae, a systolic heart murmur, and right shoulder joint swelling. C. striatum was observed in two blood culture sets. Transesophageal echocardiography revealed vegetation in the right aortic coronary cusp. Arthrocentesis at the right shoulder aspirated pyogenic fluid and C. striatum was detected in the culture. The patient was diagnosed with infective endocarditis and septic arthritis caused by C. striatum, and ampicillin was administered based on antimicrobial susceptibility test results. The patient's condition was initially stable; however, she developed pulmonary congestion on day 56 and eventually died. An autopsy demonstrated perforation of the aortic left coronary cusp with vegetation. C. striatum may cause native valve endocarditis and native joint septic arthritis. [ABSTRACT FROM AUTHOR]

Key Clinical Message: Negative myoclonus may present in the early stages of cefepime neurotoxicity. Cefepime neurotoxicity typically presents as reduced consciousness, myoclonus, and seizures; however, negative myoclonus is uncommon. This video shows an older woman with cefepime neurotoxicity that presented as a negative myoclonus of the upper limbs. [ABSTRACT FROM AUTHOR]

This article discusses a case of Immunoglobulin-A vasculitis (IgAV) in an adult patient presenting with edema in the scalp, face, and sternocleidomastoid muscle. IgAV is a small-vessel vasculitis that primarily affects children and is characterized by IgA deposits in the vessel walls. While subcutaneous edema in the scalp and face is rare in adults, it has been occasionally reported in children. Muscle involvement in IgAV is also uncommon and typically occurs in the lower extremities. This case highlights the importance of considering exacerbating IgAV and intensifying treatment when adult patients present with edema in the head and neck. Further research is needed to understand the underlying mechanisms and optimize treatments for similar cases. [Extracted from the article]

The article describes a case of an older male patient with vacuoles, E1 enzyme, X-linked autoinflammatory somatic (VEXAS) syndrome. Topics mentioned include the manifestation of granulomatosis with polyangitis, the management of the syndrome using methotrexate and infliximab, the indication of cytogenetic analysis, and the results of the positron emission tomography scan.