Search

A series of diarylstannylenes, (Rind)2Sn: (1) [Rind = 1,1,7,7-tetra-R1-3,3,5,5-tetra-R2-s-hydrindacen-4-yl: EMind (a: R1 = Et, R2 = Me), Eind (b: R1 = R2 = Et), and MPind (c: R1 = Me, R2 = nPr)], has been obtained as purple to blue crystals by the reaction of SnX2·dioxane (X = Br or Cl) with two equiv of (Rind)Li. The less bulky EMind-based stannylene, (EMnd)2Sn: (1a), reacted with N2O gas to afford a 1,3,2,4-dioxadistannetane, (EMind)4Sn2(μ-O)2 (3a), through the dimerization of a stannanone, (EMind)2Sn=O (2a). In contrast, a similar oxidation reaction using the bulkier MPind-based stannylene, (MPind)2Sn: (1c), produced a hitherto unknown acid-base free monomeric diarylstannanone, (MPind)2Sn=O (2c), with an authentic Sn=O double bond. The stannanone 2c was highly sensitive to air and moisture but remained thermally stable at room temperature. Isolating 2c as a pure single crystalline material proved challenging due to its highly-reactive nature; however, its structural characteristics and bonding properties were discussed based on both experimental findings and computational results. The Sn=O double bond in 2c exhibits a weaker and more polarized character compared to the Ge=O double bond in the diarylgermanone, (Eind)2Ge=O (A)., (© 2025 Wiley‐VCH GmbH.)

One risk factor for anastomotic leakage (AL) after esophagectomy with retrosternal gastric reconstruction is excessive compression of the gastric tube at the thoracic inlet. In this study, we evaluated the effect of our modified procedure to reduce AL by placing the esophagogastric anastomosis below the thoracic inlet. Between January 2008 and December 2022, 174 consecutive patients underwent subtotal esophagectomy with retrosternal gastric pull up, followed by circular stapler anastomosis in our hospitals. After January 2016, the gastric tube was pulled down to place the anastomosis below the suprasternal notch. Postoperative CT then measured the level of esophagogastric anastomosis (LEA). Comparing cases before and after revision (conventional group, n = 65 vs. test group, n = 109), AL was significantly reduced from 11 (16.9%) to 3 (2.8%) cases (P = 0.002). After propensity score matching, AL was observed in 14% (8/57) and 0% (0/57) cases in the conventional and test groups, respectively (P = 0.006). Smaller circular stapler size (P < 0.001), less intraoperative blood loss (P < 0.001), and lower LEA (P < 0.001) were observed in the test group than in the conventional group. Multivariate analysis revealed that anastomotic procedure (OR [95%CI], 0.01[0.00-0.46], P = 0.008), and body mass index (OR [95%CI], 6.92[1.10-135.01], P = 0.038) were the independent risk factors for the development of AL. Our modified procedure to avoid compression of the gastric tube at the thoracic inlet is suggested to noninvasively reduce the risk of AL in the subtotal esophagectomy with retrosternal reconstruction., (© The Author(s) 2024. Published by Oxford University Press on behalf of International Society for Diseases of the Esophagus. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)