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1. Reports Outline HIV/AIDS Study Findings from Johns Hopkins University (Cognate Antigen Engagement Induces Hiv-1 Expression In Latently Infected Cd4+t Cells From People On Long-term Antiretroviral Therapy).

Subjects
SEXUALLY transmitted diseases, GENE expression, RNA viruses, RETROVIRUSES, AIDS
Abstract

The article discusses a study conducted by Johns Hopkins University on HIV/AIDS, focusing on how antigens can induce HIV-1 expression in latently infected CD4+ T cells of individuals on long-term antiretroviral therapy. The research found that antigen recognition can lead to increased HIV-1 transcription and T cell activation, potentially contributing to viral rebound upon interruption of antiretroviral therapy. The study was funded by various organizations including the NIH and Howard Hughes Medical Institute, and the findings were published in the journal Immunity. [Extracted from the article]

Published
2025

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