1. Seroreversion in HIV-Associated Bilateral CMV Retinitis: A Challenging Case Report.
- Author
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Sriram, Radhika, Mahendradas, Padmamalini, Hande, Prathiba, Patil, Aditya, Kawali, Ankush, Mishra, Sai Bhakti, Rizvi, Sara, and Shetty, Rohit
- Subjects
VIRAL load ,DIAGNOSIS of HIV infections ,CD4 lymphocyte count ,VISUAL acuity ,MEDICAL screening - Abstract
Purpose: To report a case of seroreversion in a patient with HIV-associated bilateral CMV retinitis and the challenges associated with detection of this phenomenon in late stages of HIV. Method: Retrospective single case report. Results: The clinical picture of the patient on presentation was suggestive of viral retinitis. PCR confirmed a diagnosis of CMV retinitis. Serology for HIV-1 & 2 was negative. A viral load of HIV and CD-4 count confirmed his sero status to be positive for HIV. Improvement in visual acuity and slow resolution of the lesion was noted with both anti-viral for CMV and HIV. A repeat HIV-1 testing was positive with an improvement in CD4 count. Conclusion: In highly suspicious individual, with a negative serology (post screening test) for HIV, the disease status should be confirmed by testing the individual for HIV viral load and CD4 count. [ABSTRACT FROM AUTHOR]
- Published
- 2025
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