1. European validation of the classification for the anticipated difficulty of liver transplantation.
- Author
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Sommier L, Lim C, Jeune F, Goumard C, Turco C, Salloum C, Llado L, Savier E, Perdigao F, Rousseau G, Ramos E, Lopez-Dominguez J, Cachero A, Toubert C, Roucaute S, Al Taweel B, Georges P, Poppen T, Lioret P, Herrero A, Navarro F, Heyd B, Soubrane O, Azoulay D, and Scatton O
- Subjects
- Humans, Retrospective Studies, Female, Middle Aged, Male, Risk Assessment, Risk Factors, Treatment Outcome, Adult, Reproducibility of Results, Aged, Time Factors, Length of Stay, Europe, Operative Time, Cold Ischemia, Patient Selection, Predictive Value of Tests, Liver Transplantation adverse effects, Postoperative Complications classification, Postoperative Complications etiology
- Abstract
Background: Appropriate risk stratification for the difficulty of liver transplantation (LT) is essential to guide the selection and acceptance of grafts and avoid morbidity and mortality., Methods: Based on 987 LTs collected from 5 centers, perioperative outcomes were analyzed across the 3 difficulty levels. Each LT was retrospectively scored from 0 to 10. Scores of 0-2, 3-5 and 6-10 were then translated into respective difficulty levels: low, moderate and high. Complications were reported according to the comprehensive complication index (CCI)., Results: The difficulty level of LT in 524 (53%), 323 (32%), and 140 (14%) patients was classified as low, moderate and high, respectively. The values of major intraoperative outcomes, such as cold ischemia time (p = 0.04) and operative time (p < 0.0001) increased gradually with statistically significant values among difficulty levels. There was a corresponding increase in CCI (p = 0.04), severe complication rates (p = 0.05) and length of ICU (p = 0.01) and hospital (p = 0.004) stays across the different difficulty levels., Conclusion: The LT difficulty classification has been validated., (Copyright © 2024 International Hepato-Pancreato-Biliary Association Inc. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2024
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