1. Determinants of survival following heart transplantation in adults with congenital heart disease
- Author
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Hüseyin Sicim, Pierre Emmanuel Noly, Suyash Naik, Vikram Sood, Richard G. Ohye, Jonathan W. Haft, Keith D. Aaronson, Francis D. Pagani, Ming-Sing Si, and Paul C. Tang
- Subjects
Heart transplant ,Heart failure ,Congenital heart disease ,Outcomes ,Surgery ,RD1-811 ,Anesthesiology ,RD78.3-87.3 - Abstract
Abstract Background Adult patients surviving with congenital heart disease (ACHD) is growing. We examine the factors associated with heart transplant outcomes in this challenging population with complex anatomy requiring redo-surgeries. Methods We reviewed the United Network for Organ Sharing-Standard Transplant Analysis and Research database and analyzed 35,952 heart transplants from January 1st, 2000, to September 30th, 2018. We compared transplant characteristics for ischemic cardiomyopathy (ICM) (n = 14,236), nonischemic cardiomyopathy (NICM) (n = 20,676), and ACHD (n = 1040). Mean follow-up was 6.20 ± 4.84 years. Kaplan–Meier survival curves and Cox-proportional hazards analysis were used to analyze survival data. Results Multivariable analysis confirmed that ACHD was associated greater in-hospital death compared to ICM (HR = 0.54, P
- Published
- 2024
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