4 results on '"Romano F. P."'
Search Results
2. Assessing the Optimal Tsunami Inundation Modeling Strategy for Large Earthquakes in Subduction Zones
- Author
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Scala, A., Lorito, S., Escalante Sánchez, C., Romano, F., Festa, G., Abbate, A., Bayraktar, H. B., Castro, M. J., Macías, J., and Gonzalez‐Vida, J. M.
- Abstract
Tsunamis are rare events involving several complex physical phenomena. Due to this complexity and the relative scarcity of observations, tsunami research makes extensive use of numerical simulations. For seismogenic tsunamis, the source is often modeled as an instantaneous sea‐floor displacement (IS), while the tsunami propagation and inundation is computed through a shallow water approximation (SW). Here, we investigate what is the best tsunami inundation modeling strategy for different realistic earthquake source size and duration. We use 1D earthquake‐tsunami coupled simulations of large M> 8 earthquakes in Tohoku‐like subduction zone to test for which conditions the IS and/or the SW approximations can simulate with enough accuracy the tsunami evolution. We use as a reference a time‐dependent (TD), multi‐layer, non‐hydrostatic (NH) 1D model. Source duration, and size, are based on 1D dynamic rupture simulations with realistic stress drop and rigidity. We show that slow ruptures, generating slip in the shallow part of subduction zones (e.g., tsunami earthquakes), and very large events, with an along‐dip extent comparable with the trench‐coast distance (as occurs for megathrust events) require a TD‐NH modeling, especially for regions with steep coastal bathymetry. Conversely, deeper, higher stress‐drop events can be modeled through an IS‐SW approximation. We finally show that: (a) steeper bathymetries generate larger runups and, (b) a resonant mechanism emerges with runup amplifications associated with larger source size on flatter bathymetries. These results, obtained with 1D modeling, can serve as a guide for the appropriate 2/3D simulation approach for applications ranging from fundamental tsunami science to computational‐intensive hazard assessments. In the last two decades, tsunamis originated by large earthquakes have generated major damage and, according to the World Health Organization, more than 250 k casualties (more than 200 k due to the 2004 Indian Ocean tsunami). Strategies to quantify and mitigate the associated risk are based on numerical simulations of the physical processes regulating the generation, propagation of the waves and subsequent flooding on the coast. These simulations require significant computational resources. To make simulations more affordable, numerous approximations are introduced that need to be tested. In this work, we studied which earthquakes, depending on the speed at which they deform the sea bottom when they trigger a tsunami, and on how big they are, require a more detailed modeling approach, and which ones, instead, might be accurately simulated through approximated approaches. We also show how such findings are related to different bathymetric characteristics near the coast and inland, which may enhance or reduce the tsunami effects. Slow and large ruptures (e.g., tsunami earthquakes and megathrust) require a time‐dependent, non‐hydrostatic modelingDeeper, high stress‐drop earthquakes might be modeled through an instantaneous source, shallow water approximationInundation depends on bathymetric features: larger inundations on steeper depth gradients and resonant runup amplifications are observed Slow and large ruptures (e.g., tsunami earthquakes and megathrust) require a time‐dependent, non‐hydrostatic modeling Deeper, high stress‐drop earthquakes might be modeled through an instantaneous source, shallow water approximation Inundation depends on bathymetric features: larger inundations on steeper depth gradients and resonant runup amplifications are observed
- Published
- 2024
- Full Text
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3. Percentage and main features of patients referred to a cardiac rehabilitation program who would have an indication for a GLP1 receptor agonist based on the SELECT trial criteria
- Author
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Torres Marques, J, Moranta Ribas, M E, Ferrer Oliver, J A, Trias Oliver, C, Gomez Monjo, M J, Pardo Martin, L, Company Nicolau, M, Plomer Torres, A, Gomis Fernandez, P L, Monleon Castello, M S, Garcia Gutierrez, M E, Romano, F, Vidal Barcelo, P, Buen Ruiz, M C, and Ripoll Vera, T
- Published
- 2024
- Full Text
- View/download PDF
4. Sensitivity of a mini-TEPC to radiation quality variations in clinical proton beams.
- Author
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Selva, A., Bianchi, A., Cirrone, G.A.P., Petringa, G., Romano, F., Schettino, G., and Conte, V.
- Abstract
• The sensitivity to beam quality variations of a miniaturized TEPC is studied. • Microdosimetric spectra taken in two proton beams of similar quality are compared. • Microdosimetric mean values highlight changes in track- and dose-averaged LET. • The calibrated microdosimetric RBE is consistent with cell survival data. This work aims at studying the sensitivity of a miniaturized Tissue-Equivalent Proportional Counter to variations of beam quality in clinical radiation fields, to further investigate its performances as radiation quality monitor. Measurements were taken at the CATANA facility (INFN-LNS, Catania, Italy), in a monoenergetic and an energy-modulated proton beam with the same initial energy of 62 MeV. PMMA layers were placed in front of the detector to measure at different depths along the depth-dose profile. The frequency- and dose-mean lineal energy were compared to the track- and dose-averaged LET calculated by Monte Carlo simulations. A microdosimetric evaluation of the Relative Biological Effectiveness (RBE) was performed and compared with cell survival experiments. Microdosimetric distributions measured at identical depths in the two beams show spectral differences reflecting their different radiation quality. Discrepancies are most evident at depths corresponding to the Spread-Out Bragg Peak, while spectra at the entrance and in the dose fall-off regions are similar. This can be explained by the different energy components that compose the pristine and spread-out peaks at each depth. The trend of microdosimetric mean values matches that of calculated LET averages along the entire penetration depth, and the microdosimetric estimation of RBE is consistent with radiobiological data not only at 2 Gy but also at lower dose levels, such as those absorbed by healthy tissues. The mini-TEPC is sensitive to differences in radiation quality resulting from different modulations of the proton beam, confirming its potential for beam quality monitoring in proton therapy. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
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