Search

Your search keyword '"Sampson, John H"' showing total 3 results
Start Over Author "Sampson, John H" Publication Year Range This year
3 results on '"Sampson, John H"'

1. Phase 2 study of bizaxofusp, an IL-4R targeted toxin payload, in nonresectable recurrent GBM: Comparison of overall survival with contemporaneous eligibility-matched and propensity score balanced external control arm.

Author

Sampson, John H., primary, Bexon, Martin, additional, Brem, Steven, additional, Brenner, Andrew J., additional, Coello, Melissa, additional, Das, Sunit, additional, Davi, Ruthie, additional, Desjardins, Annick, additional, Han, Seunggu Jude, additional, Kesari, Santosh, additional, Madduri Karanam, Sudhir, additional, Merchant, Rosemina, additional, Phillips, Joanna J., additional, To, Minh D, additional, Vogelbaum, Michael A., additional, Vrionis, Frank, additional, Merchant, Fahar, additional, and Butowski, Nicholas A., additional

Published
2024
Full Text
View/download PDF

2. IL-7 mediated upregulation of VLA-4 increases accumulation of adoptively transferred T lymphocytes in murine glioma.

Author

Singh, Kirit, primary, Hotchkiss, Kelly M, additional, Cook, Sarah L, additional, Noldner, Pamy, additional, Zhou, Ying, additional, Moelker, Eliese M, additional, Railton, Chelsea O, additional, Blandford, Emily E, additional, Puviindran, Bhairavy J, additional, Wallace, Shannon E, additional, Norberg, Pamela K, additional, Archer, Gary E, additional, Shaz, Beth, additional, Sampson, John H, additional, Khasraw, Mustafa, additional, and Fecci, Peter E, additional

Published
2024
Full Text
View/download PDF

3. A Supramolecular Vaccine Platform Based on α-Helical Peptide Nanofibers

Author

Wu, Yaoying, Norberg, Pamela K., Reap, Elizabeth A., Congdon, Kendra L., Fries, Chelsea N., Kelly, Sean H., Sampson, John H., Conticello, Vincent P., and Collier, Joel H.

Abstract

A supramolecular peptide vaccine system was designed in which epitope-bearing peptides self-assemble into elongated nanofibers composed almost entirely of α-helical structure. The nanofibers were readily internalized by antigen presenting cells and produced robust antibody, CD4+ T-cell, and CD8+ T-cell responses without supplemental adjuvants in mice. Epitopes studied included a cancer B-cell epitope from the epidermal growth factor receptor class III variant (EGFRvIII), the universal CD4+ T-cell epitope PADRE, and the model CD8+ T-cell epitope SIINFEKL, each of which could be incorporated into supramolecular multiepitope nanofibers in a modular fashion.

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results