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Extracellular Vesicles for Therapeutic and Diagnostic Applications provides an introduction to exosomes and extracellular vesicles, including their unique properties and characterization, before detailing the most-utilized isolation, purification, and surface engineering techniques for their preparation as therapeutic and diagnostic agents. This book reviews recent developments in interdisciplinary research on exosome structure, properties, and engineering approaches as well as their use in diagnosis and treatment of a variety of illnesses such as cancer, tuberculosis, Alzheimer's disease, ophthalmic diseases, and others. Extracellular Vesicles for Therapeutic and Diagnostic Applications is an important reference for those interested in the development and application of exosomes and extracellular vesicles as biomaterials for us in the diagnosis and treatment of disease. - Provides a step-by-step overview of exosomes and extracellular vesicles and how they can be engineered with biomaterials for use in diagnostics and treatment - Covers a broad range of biomedical applications, including cancer management, bone diseases, vaccine delivery, and many more - Offers an interdisciplinary perspective on extracellular vesicles as biomaterials for therapeutic and diagnostic applications that will appeal to a wide audience

This book provides an update on the current understanding of various aspects of bladder cancer biology and introduces clinical manifestations together with current and novel treatment aspects. Key concepts covered include epidemiology and genetic predisposition to bladder cancer, insights into the mutational events and molecular pathogenesis of bladder cancer, detailed analyses of tumor subtypes, and references to common experimental models used in the study of bladder cancer. The book addresses critical issues such as the molecular features that contribute to the development of bladder cancer, the impact of the tumor microenvironment on disease progression, and the potential of novel urine- and blood-based biomarkers for diagnosis and treatment. Innovative therapeutic applications are also explored, including targeting immune checkpoints and personalized medicine approaches. Aimed at early career and experienced researchers or clinicians alike, this volume provides an interdisciplinary understanding of bladder cancer. Delving into the biology, pathology, and clinical aspects of the disease, it serves as an indispensable resource for understanding bladder cancer's complexity.