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Lircetam (LRTM) is a drug used for the treatment of epilepsy. The disposal of expired LRTM poses environmental risks, yet it retains active components that can be repurposed. This research investigates the application of expired LRTM as a corrosion inhibitor for low-carbon steel (LCS) in a 1 M HCl solution. Electrochemical methods, including Tafel polarization (PDP) and electrochemical impedance spectroscopy (EIS), alongside weight loss measurements, were employed to evaluate the efficacy of LRTM in protecting LCS against corrosion. The highest inhibition efficiencies was reported 98.16%, at 60 ppm optimal concentration. The adsorption behavior of LRTM molecules follows the Langmuir isotherm model. Surface analysis through scanning electron microscopy (SEM) and atomic force microscopy (AFM) showed that the LCS surface remained largely unaffected by the acid solution in the presence of LRTM. Contact angle (CA) measurements revealed that the adsorption of LRTM molecules increased the hydrophobicity of the LCS surface. LRTM acts as a mixed-type inhibitor, impeding both anodic and cathodic reactions. Density functional theory (DFT) calculations and molecular dynamics (MD) simulations provided further insight into the chemical interactions between LRTM and the LCS surface. This research introduces the novel application of expired lircetam, highlighting its non-toxic nature and cost-effectiveness, making it a promising alternative for corrosion prevention in industrial applications. This study investigates the dual role of Lircetum in addressing expired pharmaceutical waste and developing an efficient corrosion inhibitor for LCS in acidic environments. Repurposing expired Lircetum provides a sustainable solution to environmental hazards while demonstrating high corrosion inhibition efficiency.

Ovarian carcinoma is a leading cause of death in gynecological cancers, making early detection crucial for improving survival rates. C-reactive protein (CRP) has shown promise as a cost-effective biomarker to distinguish ovarian carcinoma from benign ovarian masses. Elevated CRP levels are associated with an increased risk of ovarian cancer. This cross-sectional study included 87 patients: 59 with ovarian carcinoma and 28 with ovarian cysts. The aim was to evaluate CRP as a diagnostic marker to improve early detection and clinical management of ovarian carcinoma. CRP levels were measured using the enzyme-linked immunosorbent assay method. Statistical analysis was conducted to assess the differences in CRP levels between the ovarian carcinoma group and the ovarian cyst group. All statistical analyses were performed using the Statistical Program for Social Sciences (IBM SPSS 24, IL, USA). Most subjects in the study were 50 years old or younger (69%) and had ovarian carcinoma (67.8%). Age over 50 [odds ratio (OR) 5.71, p=0.01] and menopausal status (OR 4.72, p=0.01) were significant risk factors for ovarian carcinoma. No significant difference in CRP levels was found between ovarian carcinoma and ovarian cyst patients (p=0.23). Based on the results, CRP cannot be used as an effective predictor to differentiate ovarian carcinoma from ovarian cysts.

This study designs an automated bathing and cage cleaning system for Murai Batu birds based on the Internet of Things (IoT) using the NodeMCU ESP32 microcontroller. The system integrates a turbidity sensor to monitor water clarity, an ultrasonic sensor to measure water level, and a load cell sensor to detect waste weight. Additionally, a PIR sensor is used to detect the bird's presence, while a stepper motor and relay are employed to automate the opening and closing of the door. Cage cleaning is performed by operating a belt conveyor driven by a DC motor, and water replacement is conducted using a water pump. All components are controlled by the NodeMCU ESP32, with monitoring facilitated through the Telegram application. The implementation results demonstrate that the system is effective, achieving sensor accuracies of 95.4%, 97.7%, and 97.36%, respectively, and providing convenience for bird owners in managing and monitoring the system remotely.

The concept of mindful parenting, derived from the broader framework of mindfulness, has gained increasing recognition in Indonesian parenting practices over recent years. However, the Interpersonal Mindfulness in Parenting (IM-P) instrument, which possesses strong psychometric properties, has not yet been available in Bahasa. The purpose of this study is to adapt the IM-P instrument into a valid and reliable Indonesian version. The IM-P was translated and adapted into Indonesian, involving a sample of 735 parents (M = 36.63; SD = 7.354) with children aged 3 to 17 years. Using a random sampling procedure, the first sample (n = 367) was used for Exploratory Factor Analysis (EFA), while the second sample (n = 368) was used for Confirmatory Factor Analysis (CFA). The study revealed that the Indonesian version of the IM-P consists of 20 items and 4 dimensions: Emotional Awareness of Self and Child, Self-Regulation in Parenting, Non-judgmental and Compassion for Child, and Non-judgmental and Compassion for Self. Overall, the IM-P Indonesia demonstrated good reliability. Additionally, the IM-P Indonesia showed a significant negative correlation with parenting stress, except for the dimension of Non-judgmental and Compassion for Self. These findings suggest that the IM-P is a valid and reliable measure for use within the Indonesian population.

Background: The diversity of batik motif designs is one of the key factors driving public interest in batik. In the batik industry, particularly among Small and Medium Enterprises (SMEs), innovation in creating new batik motifs presents a significant challenge to the sustainability of the business in Indonesia. Therefore, this study focuses on one of the SME batik businesses in Bogor. Purpose: The aim of this study is to explore the mapping process involved in creating the Tilu Sauyunan batik motif, a signature design of Bogor City, at the Handayani Geulis Batik Bogor enterprise. Design/Methodology/Approach: This study employs a qualitative approach using the design thinking method to analyze the problems and solutions in the batik creation process. Findings/Results: The analysis reveals that applying the design thinking method to the creation of the Tilu Sauyunan batik motif successfully establishes a visual identity that encapsulates the cultural essence and identity of Bogor. Conclusion: The design thinking approach demonstrated in this study effectively integrates elements and icons of Bogor into the Tilu Sauyunan batik motif, resulting in an appealing and distinctive visual identity. Originality/Value (State of the Art): Handayani Geulis Batik Bogor is a rapidly growing SME in the Indonesian batik industry. Through the innovative efforts of its owner and support from the Indonesian government, the business has expanded internationally. Positioning the Tilu Sauyunan batik motif as a cultural identity and icon of Bogor has the potential to drive further business growth and recognition. Keywords: bogor batik, design thinking, indonesian batik, local wisdom, visual identity

Participatory rural appraisal (PRA) methods have a special place in improving the health and well-being of the rural population. In the global vision to deliver contextual medical education to benefit the local population, exposure of medical students to participatory rural appraisal methods plays a vital role. However, all these benefits can only materialize, once we systematically plan and execute the training of medical students, and this essentially requires the adoption of an instructional design. Analyze-Design-Development-Implementation-Evaluation (ADDIE) is one of the most frequently used instructional designs in the field of medical education, owing to its simplicity. To conclude, participatory rural appraisal methods carry immense significance in the delivery of contextual medical education and in improving the health standards of the local population. The ADDIE instructional design is an effective approach to planning and conducting training of medical students on PRA methods.

The Compton Spectrometer and Imager balloon payload (COSI-Balloon) is a wide field-of-view Compton gamma-ray telescope that operates in the 0.2–5 MeV bandpass. COSI-Balloon had a successful 46 day flight in 2016 during which the instrument observed the Crab Nebula, Cygnus X-1, and Centaurus A. Using the data collected by the COSI-Balloon instrument during this flight, we present the source flux extraction of signals from the variable balloon background environment and produce images of these background-dominated sources by performing Richardson–Lucy deconvolutions. We also present the spectra measured by the COSI-Balloon instrument, compare and combine them with measurements from other instruments, and fit the data. The Crab Nebula was observed by COSI-Balloon, and we obtain a measured flux in the energy band 325–480 keV of (4.5 ± 1.6) × 10 ^3 ph cm ^−2 s ^−1 . The model that best fits the COSI-Balloon data combined with measurements from NuSTAR and Swift-BAT is a broken power law with a measured photon index Γ = 2.20 ± 0.02 above the 43 keV break. Cygnus X-1 was also observed during this flight, and we obtain a measured flux of (1.4 ± 0.2) × 10 ^3 ph cm ^−2 s ^−1 in the same energy band and a best-fit result (including data from NuSTAR, Swift-BAT, and INTEGRAL/IBIS) was a cutoff power law with a high-energy cutoff energy of 138.3 ± 1.0 keV and a photon index of Γ = 1.358 ± 0.002. Finally, we present the measured spectrum of Centaurus A and our best model fit to a power law with a photon index of Γ = 1.73 ± 0.01.

The Compton Spectrometer and Imager balloon payload (COSI-Balloon) is a wide field-of-view Compton gamma-ray telescope that operates in the 0.2–5 MeV bandpass. COSI-Balloon had a successful 46 day flight in 2016 during which the instrument observed the Crab Nebula, Cygnus X-1, and Centaurus A. Using the data collected by the COSI-Balloon instrument during this flight, we present the source flux extraction of signals from the variable balloon background environment and produce images of these background-dominated sources by performing Richardson–Lucy deconvolutions. We also present the spectra measured by the COSI-Balloon instrument, compare and combine them with measurements from other instruments, and fit the data. The Crab Nebula was observed by COSI-Balloon, and we obtain a measured flux in the energy band 325–480 keV of (4.5 ± 1.6) × 103 ph cm−2 s−1. The model that best fits the COSI-Balloon data combined with measurements from NuSTAR and Swift-BAT is a broken power law with a measured photon index Γ = 2.20 ± 0.02 above the 43 keV break. Cygnus X-1 was also observed during this flight, and we obtain a measured flux of (1.4 ± 0.2) × 103 ph cm−2 s−1 in the same energy band and a best-fit result (including data from NuSTAR, Swift-BAT, and INTEGRAL/IBIS) was a cutoff power law with a high-energy cutoff energy of 138.3 ± 1.0 keV and a photon index of Γ = 1.358 ± 0.002. Finally, we present the measured spectrum of Centaurus A and our best model fit to a power law with a photon index of Γ = 1.73 ± 0.01. [ABSTRACT FROM AUTHOR]

Background: Ventricular septal defect (VSD) is one of the critical risk factors for brain abscess. The unsterile blood in uncontrolled cyanotic congenital heart disease cases will travel to the brain after escaping the filtration mechanism and cause brain abscess. Case: A 40-year-old female presented with a two-week course of moderate headaches, worsening severely four days before admission. Neurological manifestations included attention deficits, dysarthria, right-sided hemiparesis, and proper facial palsy. Laboratory findings indicated leukocytosis and polycythemia. Echocardiography revealed VSD. Brain MRI with contrast suggested a single abscess lesion in the left occipital lobe. A histopathological examination confirmed the diagnosis. Antibiotics were administered during hospitalization, with outpatient treatment afterward. A one-month follow-up revealed new symptoms and a subsequent surgical excision. Discussion: Brain abscess remains a challenging and life-threatening case despite advanced diagnostic techniques. Uncontrolled cyanotic heart disease might be an essential risk factor for brain abscess occurrence. Thorough diagnostic examinations must be conducted to establish the diagnosis. The optimal empirical-targeted antibiotic treatment is a cornerstone of management. After antibiotic therapy, a surgical approach must be considered in lesions with large-size or nonoptimal size reduction. It is essential to comprehensively manage brain abscesses and their etiology to reduce the recurrence rate. Conclusion: Brain abscess associated with uncontrolled cyanotic congenital heart disease requires comprehensive treatment involving antibiotics and surgery. Addressing underlying causes and cost-effective follow-ups with clinical and monthly imaging assessments are essential. [ABSTRACT FROM AUTHOR]

Background: Moyamoya vasculopathy (MMV), like Moyamoya disease (MMD) and Moyamoya syndrome (MMS), is a rare chronic cerebrovascular angiopathy, especially in elderly patients. The incidence onset of MMV was unique with bimodal peak age: 5-10 years old and 25-49 years old. Case: A 61-year-old female complained of sudden onset left-sided hemiparesis one month before admission, headache, and forgetfulness. She had a history of diabetes mellitus for 3 years--neurological physical examination found left hemiparesis with motoric strength 4/5. Laboratory findings are unremarkable. A brain MRI with contrast showed infarcts in subcortical regions. Her cerebral DSA examination suggested diffuse multiple stenosis in the anterior circulation and total occlusion of the left external and internal carotid artery. "Puff of smoke" and "champagne-bottle-like neck sign" were found in DSA imaging, typical signs of MMD. She received aspirin 80 mg as her secondary prevention of another stroke event. Discussion: Our study showed MMV cases at elderly onset, which is similar to a prior small study with a mean age of 60 years old. Previous studies mentioned hypertension (44%) and diabetes mellitus (16%) were found in older MMD patients. The patient was given aspirin 80mg daily. Precautions in this case include taking lifelong antiplatelet, managing diabetes mellitus, and implementing lifestyle modification. This treatment approach was directed to lower the attendant risk of ischemic stroke. Conclusion: We report a case of MMV, which was considered a rare case and a cause of stroke event. The management of this case was directed to control the coexisting condition of ischemic stroke using antiplatelet drugs and risk factor management. [ABSTRACT FROM AUTHOR]

In an increasingly complex global business environment, effective corporate governance is one of the main pillars to maintain economic stability and encourage sustainable growth in the financial sector. This study aims to analyze the Effect of Share Ownership Concentration, Audit Committee Meeting Frequency, Type of External Auditor, and Risk Monitoring Committee Size on Operational Risk Disclosure in Non-Bank Financial Services Institutions (LJKNB) for the 2019-2023 Period. The content analysis method was used to collect operational risk disclosure data from the annual reports of 42 LJKNB listed on the IDX during the period 2019 to 2023. Using GLS regression analysis, this study shows the influence of governance on the disclosure of operational risks quantitatively and qualitatively. The results show that the concentration of share ownership, the number of audit committee meetings, and the external auditors of the Big 4 have a significant positive effect on the disclosure of quantitative operational risks, while the number of risk monitoring committees has a significant negative effect. The four governance variables did not have a significant effect on the qualitative disclosure of operational risks. [ABSTRACT FROM AUTHOR]

Myofibroblastoma is a rare mesenchymal tumour known for its benign nature but complex diagnostic pathway. A woman in her 40s presented with a painless breast mass, initially reported as a fibroadenoma on ultrasound mammography and as a benign to borderline phyllodes tumour on fine needle aspiration cytology. Contrast-enhanced CT was reported as carcinoma of the breast with Breast Imaging and Reporting Data System (BIRADS)-6. Based on these findings, a modified right radical mastectomy was performed. This case highlights the limitations of radiological modalities in diagnosing myofibroblastoma due to its diverse morphological spectrum. The definitive diagnosis was established through extensive histopathological examination and immunohistochemistry, which demonstrated the tumour’s unique immunoprofile, showing strong positivity for CD34 and focal positivity for desmin and Bcl-2. This case underscores the role of histopathology and immunohistochemistry in distinguishing myofibroblastoma from other breast lesions, emphasising the need for high diagnostic accuracy and thorough evaluation to guide appropriate management and avoid unnecessary, aggressive treatments. [ABSTRACT FROM AUTHOR]