194 results on '"Somogyi, A."'
Search Results
2. A Randomized Exchange Algorithm for Optimal Design of Multi-Response Experiments
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Somogyi, Pál, Rosa, Samuel, and Harman, Radoslav
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Statistics - Computation ,Statistics - Methodology ,62K05, 90C25 - Abstract
Despite the increasing prevalence of vector observations, computation of optimal experimental design for multi-response models has received limited attention. To address this problem within the framework of approximate designs, we introduce mREX, an algorithm that generalizes the randomized exchange algorithm REX (J Am Stat Assoc 115:529, 2020), originally specialized for single-response models. The mREX algorithm incorporates several improvements: a novel method for computing efficient sparse initial designs, an extension to all differentiable Kiefer's optimality criteria, and an efficient method for performing optimal exchanges of weights. For the most commonly used D-optimality criterion, we propose a technique for optimal weight exchanges based on the characteristic matrix polynomial. The mREX algorithm is applicable to linear, nonlinear, and generalized linear models, and scales well to large problems. It typically converges to optimal designs faster than available alternative methods, although it does not require advanced mathematical programming solvers. We demonstrate the application of mREX to bivariate dose-response Emax models for clinical trials, both without and with the inclusion of covariates.
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- 2024
3. The 2024 release of the ExoMol database: molecular line lists for exoplanet and other hot atmospheres
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Tennyson, Jonathan, Yurchenko, Sergei N., Zhang, Jingxin, Bowesman, Charles A., Brady, Ryan P., Buldyreva, Jeanna, Chubb, Katy L., Gamache, Robert R., Gorman, Maire N., Guest, Elizabeth R., Hill, Christian, Kefala, Kyriaki, Lynas-Gray, A. E., Mellor, Thomas M., McKemmish, Laura K., Mitev, Georgi B., Mizus, Irina I., Owens, Alec, Peng, Zhijian, Perri, Armando N., Pezzella, Marco, Polyansky, Oleg L., Qu, Qianwei, Semenov, Mikhail, Smola, Oleksiy, Solokov, Andrei, Somogyi, Wilfrid, Upadhyay, Apoorva, Wright, Samuel O. M., and Zobov, Nikolai F.
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Astrophysics - Astrophysics of Galaxies - Abstract
The ExoMol database (www.exomol.com) provides molecular data for spectroscopic studies of hot atmospheres. These data are widely used to model atmospheres of exoplanets, cool stars and other astronomical objects, as well as a variety of terrestrial applications. The 2024 data release reports the current status of the database which contains recommended line lists for 91 molecules and 224 isotopologues giving a total of almost 10$^{12}$ individual transitions. New features of the database include extensive "MARVELization" of line lists to allow them to be used for high resolutions studies, extension of several line lists to ultraviolet wavelengths, provision of photodissociation cross sections and extended provision of broadening parameters. Some of the in-house data specifications have been rewritten in JSON and moved to conformity with other international standards. Data products, including specific heats, a database of lifetimes for plasma studies, and the ExoMolHR web app which allows exclusively high resolution data to be extracted, are discussed.
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- 2024
4. LinApart: optimizing the univariate partial fraction decomposition
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Chargeishvili, Bakar, Fekésházy, Levente, Somogyi, Gábor, and Van Thurenhout, Sam
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Computer Science - Symbolic Computation ,High Energy Physics - Phenomenology ,High Energy Physics - Theory - Abstract
We present LinApart, a routine designed for efficiently performing the univariate partial fraction decomposition of large symbolic expressions. Our method is based on an explicit closed formula for the decomposition of rational functions with fully factorized denominators. We provide implementations in both the Wolfram Mathematica and C languages, made available at https://github.com/fekeshazy/LinApart . The routine can provide very significant performance gains over available tools such as the Apart command in Mathematica., Comment: 22 pages, 5 figures
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- 2024
5. All-order Feynman rules for leading-twist gauge-invariant operators in QCD
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Somogyi, G. and Van Thurenhout, S.
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High Energy Physics - Phenomenology ,High Energy Physics - Theory - Abstract
We present the Feynman rules for leading-twist gauge-invariant quark and gluon operators with an arbitrary number of total derivatives and applicable to any order in perturbation theory. This generalizes previous results and constitutes a necessary ingredient in the computation of the matrix elements of the corresponding operators. The results are written in a form appropriate for implementation in a computer algebra system. To illustrate the latter we provide implementations in Mathematica and FORM, which are made available at https://github.com/vtsam/NKLO., Comment: 22 pages, LaTex, 9 figures, v2: major revision: conventions for quark operator rules changed and Feynman rules for gluon operators were added
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- 2024
6. Differential neurocognitive profiles in adult attention-deficit/hyperactivity disorder subtypes revealed by the Cambridge Neuropsychological Test Automated Battery
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Somogyi, Szilvia, Kilencz, Tünde, Szőcs, Katalin, Klein, Izabella, Balogh, Lívia, Molnár, Rebeka, Bálint, Sára, Pulay, Attila J., Nemoda, Zsófia, Baradits, Máté, and Réthelyi, János M.
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- 2024
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7. The Effects of a School-Based Mindfulness Programme (Paws b) on Empathy and Prosocial Behaviour: A Randomised Controlled Trial
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Crompton, Katie, Kaklamanou, Daphne, Fasulo, Alessandra, and Somogyi, Eszter
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- 2024
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8. Applications of artificial intelligence in nanotechnology
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Shahad Eabd Alrida, Ola Obed, Elaf Taha, Thamer Abdullah, Mustafa Hathal, and Viola Somogyi
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nanomaterials ,machine learning ,nanocomposites ,artificial neural networks ,molecular design ,artificial intelligence ,nanotechnology ,ai ,Science ,Technology - Abstract
Artificial intelligence (AI) is emerging as a prominent technological advancement. It is the act of replicating human intelligence for many purposes. In contrast to conventional methodologies, artificial intelligence (AI) is undergoing tremendous advancements. The present state of artificial intelligence (AI) technology enables them to effectively address numerous intricate difficulties with proficiency comparable to a human's. The significance of advancements in AI is particularly evident in machine learning, where the techniques and algorithms are effectively applied to address many problems, including those in nanotechnology. In contemporary nanotechnology, it is crucial to expedite the search for the most favorable synthesis parameters while developing novel nanomaterials. The convergence of machine learning and nanotechnology necessitates a comprehensive examination of existing data on the application of artificial intelligence (AI) in addressing challenges in the nanomaterials science field. This review should encompass various stages, including computer design, chemical synthesis, and diagnostics of the resultant nanomaterials. Significant emphasis is placed on employing machine-learning technologies to investigate the thermal and dynamic characteristics of nanofluids, the sorption processes of nanocomposites, the catalytic activity of nanoparticles, and the toxicity of nanoparticles. Additionally, these technologies are utilized to address nanosensor issues and process experimental data acquired during the diagnostics of different nanomaterial properties.
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- 2024
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9. Suburbanization in Multi-ethnic Area – Conflicts and Local Strategies
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Balizs, Dániel and Somogyi, Kitti
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suburbanization ,local strategies ,ethnicity ,bratislava ,Geography. Anthropology. Recreation - Abstract
The effects of suburbanization can be examined from several aspects, but beyond the individual decisions that initiated it, the real estate market aspects, or the transformation of land use, the effects on local communities and their reactions are rarely highlighted in professional circles. In our work within the agglomeration of Bratislava, the Slovak capital, we researched individual and collective opinions on suburbanization, as well as the questions and potential conflict situations arising among members of the “host community.” A striking element of the study area is that migration also means a change in the linguistic environment, as the newcomers often arrive from a predominantly Slovakspeaking city to an area mostly inhabited by the Hungarian minority. This adds additional dimensions to suburbanization and the responses it generates. Experiences show that the municipalities affected by the process use independent, yet in certain respects similar, strategies to manage it, and as part of these strategies, the ethnic factor also appears prominently in some topics.
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- 2024
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10. All-order Feynman rules for leading-twist gauge-invariant operators in QCD
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G. Somogyi and S. Van Thurenhout
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Astrophysics ,QB460-466 ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Abstract We present the Feynman rules for leading-twist gauge-invariant quark and gluon operators with an arbitrary number of total derivatives and applicable to any order in perturbation theory. This generalizes previous results and constitutes a necessary ingredient in the computation of the matrix elements of the corresponding operators. The results are written in a form appropriate for implementation in a computer algebra system. To illustrate the latter we provide implementations in Mathematica and FORM, which are made available at https://github.com/vtsam/NKLO . Graphical abstract
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- 2024
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11. Assessment of trace and macroelement accumulation in cyprinid juveniles as bioindicators of aquatic pollution: effects of diets and habitat preferences
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Krisztián Nyeste, Nurfatin Zulkipli, Ifeanyi Emmanuel Uzochukwu, Dóra Somogyi, László Nagy, István Czeglédi, Sándor Harangi, Edina Baranyai, Edina Simon, Sándor Alex Nagy, Iliana Velcheva, Vesela Yancheva, and László Antal
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Heavy metals ,Fish ,Habitat preference ,Trophic level ,Diet ,Pollution ,Medicine ,Science - Abstract
Abstract Juveniles of three cyprinids with various diets and habitat preferences were collected from the Szamos River (Hungary) during a period of pollution in November 2013: the herbivorous, benthic nase (Chondrostoma nasus), the benthivorous, benthic barbel (Barbus barbus), and the omnivorous, pelagic chub (Squalius cephalus). Our study aimed to assess the accumulation of these elements across species with varying diets and habitat preferences, as well as their potential role in biomonitoring efforts. The Ca, K, Mg, Na, Cd, Cr, Cu, Fe, Mn, Pb, Sr, and Zn concentration was analyzed in muscle, gills, and liver using MP-AES. The muscle and gill concentrations of Cr, Cu, Fe, and Zn increased with trophic level. At the same time, several differences were found among the trace element patterns related to habitat preferences. The trace elements, including Cd, Pb, and Zn, which exceeded threshold concentrations in the water, exhibited higher accumulations mainly in the muscle and gills of the pelagic chub. Furthermore, the elevated concentrations of trace elements in sediments (Cr, Cu, Mn) demonstrated higher accumulation in the benthic nase and barbel. Our findings show habitat preference as a key factor in juvenile bioindicator capability, advocating for the simultaneous use of pelagic and benthic juveniles to assess water and sediment pollution status.
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- 2024
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12. Early and selective localization of tau filaments to glutamatergic subcellular domains within the human anterodorsal thalamus
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Sárkány, Barbara, Dávid, Csaba, Hortobágyi, Tibor, Gombás, Péter, Somogyi, Peter, Acsády, László, and Viney, Tim J.
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- 2024
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13. Pharmacokinetic and neuroimmune pharmacogenetic impacts on slow-release morphine cancer pain control and adverse effects
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Barratt, Daniel T., Klepstad, Pål, Dale, Ola, Kaasa, Stein, and Somogyi, Andrew A.
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- 2024
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14. Generalized Formal Model-Verifier: A Formal Approach for Verifying Static Models
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Somogyi, Norbert and Mezei, Gergely
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- 2024
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15. Young sanctuary-living chimpanzees produce more communicative expressions with artificial objects than with natural objects
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Violet Gibson, Derry Taylor, Sarah Salphati, Eszter Somogyi, Iris Nomikou, and Marina Davila-Ross
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object use ,language evolution ,vocalizations ,primate communication ,tool use ,Science - Abstract
In humans, interactions with objects are often embedded in communicative exchanges. Objects offer unique affordances to explore, carry functions and hold cultural relevance, which can shape children’s interactions and communication. Research indicates that the use of artificial objects, such as certain toys, helps promote pre-linguistic communication, consequently impacting language development. Given that chimpanzees use objects extensively compared to other great apes, and considering the differences between chimpanzees and bonobos in intrinsic motivation for tool use and the extended developmental period during which they learn to use objects, it is reasonable to expect that objects may influence chimpanzees’ communication. Here, we examined interactions of 31 immature sanctuary-living chimpanzees with non-novel artificial and natural objects and tested their vocal and facial expressions, applying methods previously designed for children. Our results showed an increase in these expressions associated with artificial objects. These findings provide the first empirical evidence that chimpanzee communicative expressions may be influenced by inherent properties of objects, potentially promoting varied communication, comparable to the impact distinctive objects have on pre-linguistic children. By exploring this connection between object-centric interactions and communication, this study reveals deep phylogenetic roots where objects may have shaped great ape communication and possibly evolutionary foundations of language.
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- 2024
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16. Changes in primitive reflexes in older adults and their relationship to mental health indices: An experimental investigation
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Erzsébet Stephens-Sarlós, Eliza Toth, Ferenc Ihász, Zoltán Alföldi, Angéla Somogyi, and Attila Szabo
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Aging ,Cognitive function ,Intervention ,Mental health ,Psychological measures ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
The reemergence of primitive reflexes (PRs) in older age is related to cognitive impairment. Currently, there are no means to prevent or slow their reappearance, but research evidence exists for their control in children. Therefore, this experiment investigated whether a 16-week special sensorimotor exercise program could benefit older adults and whether the intervention-induced changes (if any) may be associated with various indices of mental health. Of 115 adults over 60, 95 completed the study (mean age = 76.37 ± SD = 7.04 years, 22 % men). The experimental group (n = 38) showed an almost threefold decline in PRs compared to controls. In contrast, the control group (n = 57) exhibited a nearly threefold increase in PRs compared to the intervention group. Cognitive function increased in the experimental but not in the control group. Changes in PRs over the 16-week intervention were positively related to negative mental health indices (hopelessness and perceived stress) and negatively related to well-being. These findings suggest that the here-presented mild sensorimotor exercises could affect older adults' reemerging PRs and that changes in PRs are associated with mental health benefits. These results may open new research avenues toward preventing cognitive and psychological decline in older adults.
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- 2024
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17. Nagyszombat hajnalán
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Szilvia Somogyi
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zsinattörténet ,egyháztörténet ,16. század ,zsinati határozatok és könyvnyomtatás ,Bornemisza Pál ,nyitrai adminisztrátor ,Religion (General) ,BL1-50 - Abstract
Jelen tanulmány azt vizsgálja, hogy mi lett a sorsa a mohácsi csatavesztést követően a „középkori magyar zsinati táj” normaszövegének, a késő középkori esztergomi szinodális könyvnek. Ezeket a határozatokat a középkori Magyar Királyságban csaknem másfél évszázadig használták a hazai egyházmegyék. Milyen tünetei voltak a középkori szöveg elavulásának? Hogyan nyúltak hozzá a magyar főpapok e szöveghez a nagyszombati zsinat (1560) előtt? Azonnal elfeledték? Módosították? Hogyan állt szolgálatába a technikai újítás, azaz a nyomtatás ennek a zsinati tevékenységnek? Az 1526 és 1560 közötti, átmenetinek tekinthető korszak három történeti forrásának vizsgálatával a fenti kérdésekre keresem a választ. E három forrás a Váraljai Szaniszló szepesi prépost által 1545-ben tartott zsinat ordójának egy kora újkori másolata, a Bornemisza Pál nyitrai adminisztrátor által az 1494-es nyitrai egyházmegyei zsinati határozatok mellékleteként 1560-ban kinyomtatott annotációk, valamint a nagyszombati zsinatot megelőző 1559-es pozsonyi püspökgyűlés jegyzőkönyve. E források mindegyikre nem csak az átmeneti korszak zsinati tevékenységének értékelése szempontjából tartalmaz értékes adatokat, hanem éppúgy a középkori egyház korábbi történetét kutatók számára is számos, megfontolás tárgyát képező kérdést vet fel.
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- 2024
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18. Managing Climate Change Risks in Critical Infrastructure Protection with Examples from the European Financial Sector
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Somogyi, Tamás, Masys, Anthony J., Editor-in-Chief, Bichler, Gisela, Advisory Editor, Bourlai, Thirimachos, Advisory Editor, Johnson, Chris, Advisory Editor, Karampelas, Panagiotis, Advisory Editor, Leuprecht, Christian, Advisory Editor, Morse, Edward C., Advisory Editor, Skillicorn, David, Advisory Editor, Yamagata, Yoshiki, Advisory Editor, Kovács, Tünde Anna, editor, Nyikes, Zoltán, editor, Berek, Tamás, editor, Daruka, Norbert, editor, and Tóth, László, editor
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- 2024
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19. Disease trajectories in interstitial lung diseases – data from the EXCITING-ILD registry
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Katharina Buschulte, Hans-Joachim Kabitz, Lars Hagmeyer, Peter Hammerl, Albert Esselmann, Conrad Wiederhold, Dirk Skowasch, Christoph Stolpe, Marcus Joest, Stefan Veitshans, Marc Höffgen, Phillen Maqhuzu, Larissa Schwarzkopf, Andreas Hellmann, Michael Pfeifer, Jürgen Behr, Rainer Karpavicius, Andreas Günther, Markus Polke, Philipp Höger, Vivien Somogyi, Christoph Lederer, Philipp Markart, and Michael Kreuter
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ILD ,IPF ,Progression ,Mortality ,Risk factors ,Diseases of the respiratory system ,RC705-779 - Abstract
Abstract Background Interstitial lung diseases (ILD) comprise a heterogeneous group of mainly chronic lung diseases with different disease trajectories. Progression (PF-ILD) occurs in up to 50% of patients and is associated with increased mortality. Methods The EXCITING-ILD (Exploring Clinical and Epidemiological Characteristics of Interstitial Lung Diseases) registry was analysed for disease trajectories in different ILD. The course of disease was classified as significant (absolute forced vital capacity FVC decline > 10%) or moderate progression (FVC decline 5–10%), stable disease (FVC decline or increase
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- 2024
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20. Guidance on mucositis assessment from the MASCC Mucositis Study Group and ISOO: an international Delphi studyResearch in context
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Ragda Abdalla-Aslan, Pierluigi Bonomo, Dorothy Keefe, Nicole Blijlevens, Katrina Cao, Yin Ting Cheung, Eduardo Rodrigues Fregnani, Robert Miller, Judith Raber-Durlacher, Joel Epstein, Ysabella Van Sebille, Elisa Kauark-Fontes, Abhishek Kandwal, Emma McCurdy-Franks, Joel Finkelstein, Victoria McCarvell, Yehuda Zadik, Giulia Ottaviani, Rui Amaral Mendes, Caroline Margina Speksnijder, Hannah Rose Wardill, Paolo Bossi, Alexa Laheij, Arghavan Tonkaboni, Jacqui Scott, Rania Abasaeed, Adel Kauzman, Adriana Do Socorro Lima Flato, Adwaita Gore, Anne-Marie Hardman, Agnes Horvath, Allan Hovan, Aisha Al-Jamaei, Aya koizumi, Alan Santos-Silva, Alessandra Majorana, Alexandre Giannini, Aléxia Teixeira, Muhammad Ali Shazib, Alison Melvin, Aluísio Miranda Filho, Amanda Gruza, Amber Brown-Dahl, Amit Harilall, Amr El Maghrabi, Ana Andabak Rogulj, Ana Raphaela Curvo, Ana Laura Soares, Andrea Stringer, Andréa Moreira, Andy Kurtzweil, Angelyn Salaberry, Anne Blazy, Anne Margrete Gussgard, Anne Marie Lynge Pedersen, Annette Freidank, Anura Ariyawardana, Adrian Ramseier, Jann Arends, Ariel Blanchard, Adriana Sesti Paz, Angela Thermann, Augusto Poropat, Azael Freites-Martinez, Abdul Rahman Al-Azri, Bente Brokstad Herlofson, Sitaraman BalajiSubramanian, Barbara Ballantyne, Kivanc Bektas-Kayhan, Bengt Hasséus, Benjamin Kaffenberger, Bernar Benites, Bernice Kwong, Beth Test, Fernando Chiantia, Bo Pettersson, Bomi Framroze, Božana Lončar Brzak, Brittany Dulmage, Sorin Buga, Caroline Spekssnijder, Carlton Brown, Antonio Carlos Moura de Melo, Ana Carolina Ribeiro, Caroline Silva, Caroline Fulop, Carryn Anderson, Catherine Flaitz, Cathy Massoud, Cesar Migliorati, Callie Gross, Chiara Gandini, Charles Loprinzi, Charlotte de Mooij, Catherine Hong, Ying Chu Choi, Maria Choy, Christine Boers-Doets, Leonard Schmeel, Cibele Nagano, Maria Coeli Franco, Courtney Subramaniam, Carolyn Patrick, Catherine Poh, Cristina Neuenschwander, Cesar Virgen, Dorothea Riesenbeck, Dale Weaver, Daniel Cohen Goldemberg, Daniel Sundaresan, Daniela Nunes, Danyel Perez, Daphine Travassos, David Yang, Daniela Ribeiro, Dean Kolbinson, Deborah Buick, Deborah Saunders, Juliane De Bortolli, Deepika Chugh, Denise Markstrom, Denise Travassos, Dianna Weikel, Dimitra Galiti, Dinusha Peiris, Fedja Djordjevic, Pankaj Singhai, Douglas Peterson, Douglas Fonseca, Doreen Pon, Iuliia Kovalenko, Aleksandra Polonskaia, Rogério Caldas, Kevin Saganski, Julia Néri, Dennis Abbott, Abhijna Vithal Yergolkar, Cristina Del Conte, Januaria Passos, Katia Uezu, Paula Silva, Steven Gilbert, Keng Yeoh, Kunal Jain, Madhup Rastogi, Satheeshkumar Poolakkad Sankaran, Deborah Manne, Evgeniya Shatokhina, Esther Adebayo-Olojo, Eszter Somogyi-Ganss, Eli Ehrenpreis, Wilber Bernaola-Paredes, Eduardo Fregnani, Elaci Cardoso, Elena Bardellini, Eleni Arvanitou, Elisa Kauark Fontes, Elise Bruning, Eloise Neumann, Elsa Madureira, Marcia Ramires, Erofili Papadopoulou, Etiene Munhoz, Fred Spijkervet, Fabiana Granzotto, Fabiana Martins, Fabio Alves, Farah Mougeot, Federica Aielli, Fernanda Pigatti, Fernanda Fonseca, Firoozeh Samim, Flavia Carvalho, Florence Cuadra Zelaya, Cesar Freytes, Gabriela da Silveira, Gabriela Torino, Gabriela Martins, Geisa Silva, Gemma Caro, Gemma Bryan, Georgette Radford, Ghanyah Al-Qadami, Giorgia Albini, Gisele Mainville, Georgios Gkardiakos, Gleidston Potter, Gulbin Hoeberechts, Gordon Howarth, Grace Bradley, Gunjan Verma, Gustavo dos Santos, Margaret Randles-Guzzardi, Hanlie Engelbrecht, Hannah Wardill, Heidi Hansen, Iquebal Hasan, Hironobu Hata, Helena Ullgren, Heliton Spindola Antunes, Heloísa Laís dos Santos, Howard Weld, Helen McInnes, Hans Peter Jungbluth, Hsiaofen Weng, Ian Hewson, Ingrid Santos, Jorge Illarramendi, Ines Semendric, Rol Menge, Inger Von Bultzingslowen, Maria da Gloria de Melo, Iona Leong, Isabella Fonseca, Isadora Kalif, James Carroll, Janet Coller, Johann Beck-Mannagetta, Joanne Bowen, Jose Meurer, Ricky McCullough, Jennifer Powers, Jesus Gomez, Jimma Lenjisa, jaya Vangara, Jasna Leko, Jane Fall-Dickson, Jean-Luc Mougeot, Joan Fox, Jolien Robijns, Jonn Wu, Patricio Palma, Jaya Amaram-Davila, Jim Siderov, Juliana Dantas, Juliana Jasper, Juliana Monteiro, Julia Bruno, julie pfeffer, Julija Jovanovic Ristivojevic, Juliana Brito, Jyothsna Kuriakose, Yuji Kabasawa, Kanan Dave, Karin Barczyszyn, Karol Sartori Lima, Kate Secombe, Kate White, Kate Cooper, Kouji Katsura, Karen Biggs, Katharine Ciarrocca, Kristopher Dennis, Ken Tomizuka, Kevin Hendler, Ikuko Komo, Kristina Skallsjö, Kristy Hodgins, Katia Rupel, Keiko Tanaka, Seema Kurup, Luiz Gueiros, Larissa Agatti, Laura Garzona-Navas, Letícia Guerra, Leila Portela, Leilani Iossi, Linda Elting, Lene Baad-Hansen, Leslie Reeder, Leticia Lang, Liciane Menezes, Liliana Braun, Liliane Grando, Mathew Lim, Lina Fernandez, Lucy McKeage, Luana Campos, Luciana Simonato, Luciana Muniz, Leah van Draanen, Mieko Mizutani, Tsai-Wei Huang, Mahfujul Riad, Mahnoor Nazar, Maíra Souza, Mariana Minamisako, Manoela Pereira, Carlos Mantelato, Márcio Diniz-Freitas, Marco Montezuma, Marco Andrade, Marcos Santos, Margherita Gobbo, Maria Caterina Fortuna, Mariana Vitor, Joana Marinho, Alina Markova, Marlyse Knuchel, Marta Carlesimo, Marta Neves, Andrew Mazar, Maria Cristina Gomez Amarilla, Mark Chambers, Melissa de Araujo, Alexandre Melo, Melody Cole, Mohamed Elsayed, Monica Fliedner, Martin Hauer-Jensen, Micaela Bouchacourt, Michael Brennan, Michael Thirlwell, Michio Nakamura, Midori Nakagaki, Camila Rossi, Mireille Kaprilian, Michael Kase, Michael Dougan, Monique Stokman, Ragnhild Monsen, Alisha Morgan, Jocelyn Harding, Maryam Taleghani, Marie-Therese Genot, Mukund Seshadri, Brian Muzyka, Nancy Batista, Nancy Gadd, Naoko Tanda, Narmin Nasr, Natália Garcia, Nathan Lee, Natalia Palmier, Norman Brito-Dellan, Nancy Corbitt, Neli Pieralisi, Verônica Serrano, Nicola Alessandro Iacovelli, Norma Lúcia Sampaio, Nour Karra, Niveditha Venkatesh, Noam Yarom, Renata Cristina Borin, Olivia Lemenchick, Ondina Mendes, Ourania Nicolatou-Galitis, Vasiliy Shchitka, Paula Reis, Paulo Sérgio Santos, Paz Fernandez-Ortega, Ira Parker, Raquel García, Peter Fritz, Edmund Peters, Pamela Gardner, Pierre Saint Girons, Priya Tiwari, Pravin Chaturvedi, Tais de Moraes, Priscila Andrade, Raj Nair, Rachel Gibson, Rachita Gururaj, Raghu Thota, Rajesh Lalla, Raquel Almeida Prado, Ravikiran Ongole, George Taybos, Regina Mackey, Renata Rego, Renata Camilotti, Renata Ferrari, Renato Junior, Rene-Jean Bensadoun, Richard Logan, Roberta Sales, Roberta Zanicotti, Roberta Tunes, Rodolfo Mauceri, Rosiene Feitoza, Kathryn Ruddy, Cynthia Rybczyk, Stephanie Trager, Sachiyo Mitsunaga, Sahani Gunathilake, Rajan Saini, Viola Salvestrini, Sandip Mukhopadhyay, Sandrina Angeloz, Pramod Sankar S, Luciana S Barbosa Barbosa, Elena Volkova, Sharon Elad, Sergio Cantoreggi, Sharon Gordon, Shelly Brown, Shu Yie Janine Tam, Sibelle Faleiro, Silmara da Silva, Silvia de Oliveira, Siri Beier Jensen, Ivana Skrinjar, Sophie Beaumont, Felipe Sperandio, Sandra Reese, Steven Roser, Sachiko Seo, Stephanie van Leeuwen, Stephen Sonis, Stephen Bernard, Stephen Rajan Samuel, Stuart Taylor, Suranjan Maitra, Susanne Skulski, Suzanne Carlisle, Sylvie Louise Avon, Tomoya Yokota, Takashi Yurikusa, Tabata Santos Polvora, Tabitha Kelock, Tauana Fernandes, Taylor Wain, Timothy Brown, Tetsuhito konishi, Thalyta Amanda Ferreira, Tomoko Kataoka, Thomas Kelly, Takehiko Mori, Tomoko Higuchi, Toshiaki Saeki, Nikolaos Tsoukalas, Typhaine Maupoint De Vandeul, Masatoshi Usubuchi, Vanessa Lacerda, Vanessa Tilly, Emmanuelle Vigarios, Alessandro Villa, Vinicius Torregrossa, Vinodh Kumar Selvaraj, Viviane Sarmento, Vivien Heng, Wagner Gomes-Silva, Petter Wilberg, Wanessa Miranda e Silva, Wan Nor I'zzah Wan Mohamad Zain, Wonse Park, Wim Tissing, Yoshihiko Soga, Bella Van Sebille, and Yuhei Matsuda
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Oral mucositis ,Gastrointestinal mucositis ,Mucositis assessment tools ,Patient-reported outcome measures ,Medicine (General) ,R5-920 - Abstract
Summary: Background: Mucositis is a common and highly impactful side effect of conventional and emerging cancer therapy and thus the subject of intense investigation. Although common practice, mucositis assessment is heterogeneously adopted and poorly guided, impacting evidence synthesis and translation. The Multinational Association of Supportive Care in Cancer (MASCC) Mucositis Study Group (MSG) therefore aimed to establish expert recommendations for how existing mucositis assessment tools should be used, in clinical care and trials contexts, to improve the consistency of mucositis assessment. Methods: This study was conducted over two stages (January 2022–July 2023). The first phase involved a survey to MASCC-MSG members (January 2022–May 2022), capturing current practices, challenges and preferences. These then informed the second phase, in which a set of initial recommendations were prepared and refined using the Delphi method (February 2023–May 2023). Consensus was defined as agreement on a parameter by >80% of respondents. Findings: Seventy-two MASCC-MSG members completed the first phase of the study (37 females, 34 males, mainly oral care specialists). High variability was noted in the use of mucositis assessment tools, with a high reliance on clinician assessment compared to patient reported outcome measures (PROMs, 47% vs 3%, 37% used a combination). The World Health Organization (WHO) and Common Terminology Criteria for Adverse Events (CTCAE) scales were most commonly used to assess mucositis across multiple settings. Initial recommendations were reviewed by experienced MSG members and following two rounds of Delphi survey consensus was achieved in 91 of 100 recommendations. For example, in patients receiving chemotherapy, the recommended tool for clinician assessment in clinical practice is WHO for oral mucositis (89.5% consensus), and WHO or CTCAE for gastrointestinal mucositis (85.7% consensus). The recommended PROM in clinical trials is OMD/WQ for oral mucositis (93.3% consensus), and PRO-CTCAE for gastrointestinal mucositis (83.3% consensus). Interpretation: These new recommendations provide much needed guidance on mucositis assessment and may be applied in both clinical practice and research to streamline comparison and synthesis of global data sets, thus accelerating translation of new knowledge into clinical practice. Funding: No funding was received.
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21. An Automatic Road Surface Segmentation in Non-Urban Environments: A 3D Point Cloud Approach With Grid Structure and Shallow Neural Networks.
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Mohammad Dowajy, árpád Somogyi, árpád Barsi, and Tamas Lovas
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- 2024
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22. Changes in primitive reflexes in older adults and their relationship to mental health indices: An experimental investigation
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Stephens-Sarlós, Erzsébet, Toth, Eliza, Ihász, Ferenc, Alföldi, Zoltán, Somogyi, Angéla, and Szabo, Attila
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- 2024
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23. Large shallow lake response to anthropogenic stressors and climate change: Missing macroinvertebrate recovery after oligotrophication (Lake Balaton, East-Central Europe)
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Magyari, E.K., Szabó, Z., Falus, Gy., Móra, A., Szalai, Z., Hamerlik, L., Tóth, M., Farkas, Á., Pomogyi, P., Somogyi, B., Vörös, L., and Korponai, J.
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- 2024
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24. Patient satisfaction with different types of craniofacial prostheses
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Higgins, Kevin M., Gressmann, Kassandra, Yan, Bernie, Eskander, Antoine, Enepekides, Danny J., Blanas, Nick, and Somogyi-Ganss, Eszter
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- 2024
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25. Exploring spatiotemporal features of surface water temperature for Lake Balaton in the 21st century based on Google Earth Engine
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Li, Huan, Somogyi, Boglárka, and Tóth, Viktor
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- 2024
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26. Hospitalisation patterns in interstitial lung diseases: data from the EXCITING-ILD registry
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Katharina Buschulte, Hans-Joachim Kabitz, Lars Hagmeyer, Peter Hammerl, Albert Esselmann, Conrad Wiederhold, Dirk Skowasch, Christoph Stolpe, Marcus Joest, Stefan Veitshans, Marc Höffgen, Phillen Maqhuzu, Larissa Schwarzkopf, Andreas Hellmann, Michael Pfeifer, Jürgen Behr, Rainer Karpavicius, Andreas Günther, Markus Polke, Philipp Höger, Vivien Somogyi, Christoph Lederer, Philipp Markart, and Michael Kreuter
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ILD ,IPF ,Hospitalisation ,Prognosis ,Risk factors ,Diseases of the respiratory system ,RC705-779 - Abstract
Abstract Background Interstitial lung diseases (ILD) comprise a heterogeneous group of mainly chronic lung diseases with more than 200 entities and relevant differences in disease course and prognosis. Little data is available on hospitalisation patterns in ILD. Methods The EXCITING-ILD (Exploring Clinical and Epidemiological Characteristics of Interstitial Lung Diseases) registry was analysed for hospitalisations. Reasons for hospitalisation were classified as all cause, ILD-related and respiratory hospitalisations, and patients were analysed for frequency of hospitalisations, time to first non-elective hospitalisation, mortality and progression-free survival. Additionally, the risk for hospitalisation according to GAP index and ILD subtype was calculated by Cox proportional-hazard models as well as influencing factors on prediction of hospitalisation by logistic regression with forward selection. Results In total, 601 patients were included. 1210 hospitalisations were recorded during the 6 months prior to registry inclusion until the last study visit. 800 (66.1%) were ILD-related, 59.3% of admissions were registered in the first year after inclusion. Mortality was associated with all cause, ILD-related and respiratory-related hospitalisation. Risk factors for hospitalisation were advanced disease (GAP Index stages II and III) and CTD (connective tissue disease)-ILDs. All cause hospitalisations were associated with pulmonary hypertension (OR 2.53, p = 0.005). ILD-related hospitalisations were associated with unclassifiable ILD and concomitant emphysema (OR = 2.133, p = 0.001) as well as with other granulomatous ILDs and a positive smoking status (OR = 3.082, p = 0.005). Conclusion Our results represent a crucial contribution in understanding predisposing factors for hospitalisation in ILD and its major impact on mortality. Further studies to characterize the most vulnerable patient group as well as approaches to prevent hospitalisations are warranted.
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- 2024
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27. Synthesis, Characterization and Application of Advanced Antimicrobial Electrospun Polymers
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Maja Somogyi Škoc, Ernest Meštrović, Pierre-Alexis Mouthuy, and Iva Rezić
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synthesis ,characterization ,novel materials application ,surface modification ,electrospinning ,antimicrobial resistance (AMR) ,Organic chemistry ,QD241-441 - Abstract
The aim of this work was to synthesize, characterize and apply advanced antimicrobial biocompatible electrospun polymers suitable for medical implants for surgical repairs. Injuries to the musculoskeletal system often necessitate surgical repair, but current treatments can still lead to high failure rates, such as 40% for the repair of rotator cuff tears. Therefore, there is an urgent need for the development of new biocompatible materials that can effectively support the repair of damaged tissues. Additionally, infections acquired during hospitalization, particularly those caused by antibiotic-resistant bacteria, result in more fatalities than AIDS, tuberculosis, and viral hepatitis combined. This underscores the critical necessity for the advancement of antimicrobial implants with specialized coatings capable of combating Methicillin-resistant Staphylococcus aureus (MRSA) and Methicillin-sensitive Staphylococcus aureus (MSSA), two strains notoriously known for their antibiotic resistance. Therefore, we developed an antimicrobial coating incorporating nanoparticle mixtures using the sol-gel process and applied it to electrospun polycaprolactone (PCL) filaments, followed by thorough characterization by using spectroscopic (FTIR, Raman, NMR) microscopic (SEM and SEM-EDX), and tensile test. The results have shown that the integration of electro-spinning technology for yarn production, coupled with surface modification techniques, holds significant potential for creating antimicrobial materials suitable for medical implants for surgical repairs.
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- 2024
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28. Molecular Aspects in the Development of Type 2 Diabetes and Possible Preventive and Complementary Therapies
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Laura Simon-Szabó, Beáta Lizák, Gábor Sturm, Anikó Somogyi, István Takács, and Zsuzsanna Németh
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insulin signaling ,T2DM ,insulin resistance ,glucose intolerance ,life style ,prevention ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
The incidence of diabetes, including type 2 diabetes (T2DM), is increasing sharply worldwide. To reverse this, more effective approaches in prevention and treatment are needed. In our review, we sought to summarize normal insulin action and the pathways that primarily influence the development of T2DM. Normal insulin action involves mitogenic and metabolic pathways, as both are important in normal metabolic processes, regeneration, etc. However, through excess energy, both can be hyperactive or attenuated/inactive leading to disturbances in the cellular and systemic regulation with the consequence of cellular stress and systemic inflammation. In this review, we detailed the beneficial molecular changes caused by some important components of nutrition and by exercise, which act in the same molecular targets as the developed drugs, and can revert the damaged pathways. Moreover, these induce entire networks of regulatory mechanisms and proteins to restore unbalanced homeostasis, proving their effectiveness as preventive and complementary therapies. These are the main steps for success in prevention and treatment of developed diseases to rid the body of excess energy, both from stored fats and from overnutrition, while facilitating fat burning with adequate, regular exercise in healthy people, and together with necessary drug treatment as required in patients with insulin resistance and T2DM.
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- 2024
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29. Computational Methodologies in Synthesis, Preparation and Application of Antimicrobial Polymers, Biomolecules, and Nanocomposites
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Iva Rezić and Maja Somogyi Škoc
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computational methodologies ,polymer ,nanocomposite ,biomolecules ,antimicrobial ,Organic chemistry ,QD241-441 - Abstract
The design and optimization of antimicrobial materials (polymers, biomolecules, or nanocomposites) can be significantly advanced by computational methodologies like molecular dynamics (MD), which provide insights into the interactions and stability of the antimicrobial agents within the polymer matrix, and machine learning (ML) or design of experiment (DOE), which predicts and optimizes antimicrobial efficacy and material properties. These innovations not only enhance the efficiency of developing antimicrobial polymers but also enable the creation of materials with tailored properties to meet specific application needs, ensuring safety and longevity in their usage. Therefore, this paper will present the computational methodologies employed in the synthesis and application of antimicrobial polymers, biomolecules, and nanocomposites. By leveraging advanced computational techniques such as MD, ML, or DOE, significant advancements in the design and optimization of antimicrobial materials are achieved. A comprehensive review on recent progress, together with highlights of the most relevant methodologies’ contributions to state-of-the-art materials science will be discussed, as well as future directions in the field will be foreseen. Finally, future possibilities and opportunities will be derived from the current state-of-the-art methodologies, providing perspectives on the potential evolution of polymer science and engineering of novel materials.
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- 2024
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30. Guidance on mucositis assessment from the MASCC Mucositis Study Group and ISOO: an international Delphi study
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Laheij, Alexa, Tonkaboni, Arghavan, Scott, Jacqui, Abasaeed, Rania, Kauzman, Adel, Flato, Adriana Do Socorro Lima, Gore, Adwaita, Hardman, Anne-Marie, Horvath, Agnes, Hovan, Allan, Al-Jamaei, Aisha, koizumi, Aya, Santos-Silva, Alan, Majorana, Alessandra, Giannini, Alexandre, Teixeira, Aléxia, Shazib, Muhammad Ali, Melvin, Alison, Filho, Aluísio Miranda, Gruza, Amanda, Brown-Dahl, Amber, Harilall, Amit, El Maghrabi, Amr, Rogulj, Ana Andabak, Curvo, Ana Raphaela, Soares, Ana Laura, Stringer, Andrea, Moreira, Andréa, Kurtzweil, Andy, Salaberry, Angelyn, Blazy, Anne, Gussgard, Anne Margrete, Lynge Pedersen, Anne Marie, Freidank, Annette, Ariyawardana, Anura, Ramseier, Adrian, Arends, Jann, Blanchard, Ariel, Paz, Adriana Sesti, Thermann, Angela, Poropat, Augusto, Freites-Martinez, Azael, Al-Azri, Abdul Rahman, Herlofson, Bente Brokstad, BalajiSubramanian, Sitaraman, Ballantyne, Barbara, Bektas-Kayhan, Kivanc, Hasséus, Bengt, Kaffenberger, Benjamin, Benites, Bernar, Kwong, Bernice, Test, Beth, Chiantia, Fernando, Pettersson, Bo, Framroze, Bomi, Bonomo, Pierluigi, Brzak, Božana Lončar, Dulmage, Brittany, Buga, Sorin, Spekssnijder, Caroline, Brown, Carlton, Melo, Antonio Carlos Moura de, Ribeiro, Ana Carolina, Silva, Caroline, Fulop, Caroline, Anderson, Carryn, Flaitz, Catherine, Massoud, Cathy, Migliorati, Cesar, Gross, Callie, Gandini, Chiara, Loprinzi, Charles, de Mooij, Charlotte, Hong, Catherine, Choi, Ying Chu, Choy, Maria, Boers-Doets, Christine, Schmeel, Leonard, Nagano, Cibele, Franco, Maria Coeli, Subramaniam, Courtney, Patrick, Carolyn, Poh, Catherine, Neuenschwander, Cristina, Virgen, Cesar, Riesenbeck, Dorothea, Weaver, Dale, Goldemberg, Daniel Cohen, Sundaresan, Daniel, Nunes, Daniela, Perez, Danyel, Travassos, Daphine, Yang, David, Ribeiro, Daniela, Kolbinson, Dean, Buick, Deborah, Saunders, Deborah, De Bortolli, Juliane, Chugh, Deepika, Markstrom, Denise, Travassos, Denise, Weikel, Dianna, Galiti, Dimitra, Peiris, Dinusha, Djordjevic, Fedja, Singhai, Pankaj, Keefe, Dorothy, Peterson, Douglas, Fonseca, Douglas, Pon, Doreen, Kovalenko, Iuliia, Polonskaia, Aleksandra, Caldas, Rogério, Saganski, Kevin, Néri, Julia, Abbott, Dennis, Yergolkar, Abhijna Vithal, Del Conte, Cristina, Passos, Januaria, Uezu, Katia, Silva, Paula, Gilbert, Steven, Yeoh, Keng, Jain, Kunal, Rastogi, Madhup, Sankaran, Satheeshkumar Poolakkad, Manne, Deborah, Shatokhina, Evgeniya, Adebayo-Olojo, Esther, Somogyi-Ganss, Eszter, Ehrenpreis, Eli, Bernaola-Paredes, Wilber, Fregnani, Eduardo, Cardoso, Elaci, Bardellini, Elena, Arvanitou, Eleni, Fontes, Elisa Kauark, Bruning, Elise, Neumann, Eloise, Madureira, Elsa, Ramires, Marcia, Papadopoulou, Erofili, Munhoz, Etiene, Spijkervet, Fred, Granzotto, Fabiana, Martins, Fabiana, Alves, Fabio, Mougeot, Farah, Aielli, Federica, Pigatti, Fernanda, Fonseca, Fernanda, Samim, Firoozeh, Carvalho, Flavia, Zelaya, Florence Cuadra, Freytes, Cesar, da Silveira, Gabriela, Torino, Gabriela, Martins, Gabriela, Silva, Geisa, Caro, Gemma, Bryan, Gemma, Radford, Georgette, Al-Qadami, Ghanyah, Albini, Giorgia, Mainville, Gisele, Gkardiakos, Georgios, Potter, Gleidston, Hoeberechts, Gulbin, Howarth, Gordon, Ottaviani, Giulia, Bradley, Grace, Verma, Gunjan, Santos, Gustavo dos, Randles-Guzzardi, Margaret, Engelbrecht, Hanlie, Wardill, Hannah, Hansen, Heidi, Hasan, Iquebal, Hata, Hironobu, Ullgren, Helena, Antunes, Heliton Spindola, Laís dos Santos, Heloísa, Weld, Howard, McInnes, Helen, Jungbluth, Hans Peter, Weng, Hsiaofen, Hewson, Ian, Santos, Ingrid, Illarramendi, Jorge, Semendric, Ines, Menge, Rol, Von Bultzingslowen, Inger, Melo, Maria da Gloria de, Leong, Iona, Fonseca, Isabella, Kalif, Isadora, Carroll, James, Coller, Janet, Beck-Mannagetta, Johann, Bowen, Joanne, Meurer, Jose, McCullough, Ricky, Powers, Jennifer, Gomez, Jesus, Lenjisa, Jimma, jaya Vangara, Leko, Jasna, Fall-Dickson, Jane, Mougeot, Jean-Luc, Fox, Joan, Epstein, Joel, Robijns, Jolien, Wu, Jonn, Palma, Patricio, Amaram-Davila, Jaya, Siderov, Jim, Raber-Durlacher, Judith, Dantas, Juliana, Jasper, Juliana, Monteiro, Juliana, Bruno, Julia, julie pfeffer, Ristivojevic, Julija Jovanovic, Brito, Juliana, Kuriakose, Jyothsna, Kabasawa, Yuji, Dave, Kanan, Barczyszyn, Karin, Lima, Karol Sartori, Secombe, Kate, White, Kate, Cooper, Kate, Katsura, Kouji, Biggs, Karen, Ciarrocca, Katharine, Dennis, Kristopher, Tomizuka, Ken, Hendler, Kevin, Komo, Ikuko, Skallsjö, Kristina, Hodgins, Kristy, Rupel, Katia, Tanaka, Keiko, Kurup, Seema, Gueiros, Luiz, Agatti, Larissa, Garzona-Navas, Laura, Guerra, Letícia, Portela, Leila, Iossi, Leilani, Elting, Linda, Baad-Hansen, Lene, Reeder, Leslie, Lang, Leticia, Menezes, Liciane, Braun, Liliana, Grando, Liliane, Lim, Mathew, Fernandez, Lina, McKeage, Lucy, Campos, Luana, Simonato, Luciana, Muniz, Luciana, van Draanen, Leah, Mizutani, Mieko, Huang, Tsai-Wei, Riad, Mahfujul, Nazar, Mahnoor, Souza, Maíra, Minamisako, Mariana, Pereira, Manoela, Mantelato, Carlos, Diniz-Freitas, Márcio, Montezuma, Marco, Andrade, Marco, Santos, Marcos, Gobbo, Margherita, Fortuna, Maria Caterina, Vitor, Mariana, Marinho, Joana, Markova, Alina, Knuchel, Marlyse, Carlesimo, Marta, Neves, Marta, Mazar, Andrew, Gomez Amarilla, Maria Cristina, Chambers, Mark, Araujo, Melissa de, Melo, Alexandre, Cole, Melody, Elsayed, Mohamed, Fliedner, Monica, Hauer-Jensen, Martin, Bouchacourt, Micaela, Brennan, Michael, Thirlwell, Michael, Nakamura, Michio, Nakagaki, Midori, Rossi, Camila, Miller, Robert, Kaprilian, Mireille, Kase, Michael, Dougan, Michael, Stokman, Monique, Monsen, Ragnhild, Morgan, Alisha, Harding, Jocelyn, Taleghani, Maryam, Genot, Marie-Therese, Seshadri, Mukund, Muzyka, Brian, Batista, Nancy, Gadd, Nancy, Tanda, Naoko, Nasr, Narmin, Garcia, Natália, Lee, Nathan, Palmier, Natalia, Brito-Dellan, Norman, Corbitt, Nancy, Pieralisi, Neli, Serrano, Verônica, Iacovelli, Nicola Alessandro, Blijlevens, Nicole, Sampaio, Norma Lúcia, Karra, Nour, Venkatesh, Niveditha, Yarom, Noam, Borin, Renata Cristina, Lemenchick, Olivia, Mendes, Ondina, Nicolatou-Galitis, Ourania, Shchitka, Vasiliy, Bossi, Paolo, Reis, Paula, Santos, Paulo Sérgio, Fernandez-Ortega, Paz, Parker, Ira, García, Raquel, Fritz, Peter, Peters, Edmund, Gardner, Pamela, Girons, Pierre Saint, Tiwari, Priya, Chaturvedi, Pravin, de Moraes, Tais, Andrade, Priscila, Nair, Raj, Gibson, Rachel, Gururaj, Rachita, Abdalla-Aslan, Ragda, Thota, Raghu, Lalla, Rajesh, Mendes, Rui Amaral, Prado, Raquel Almeida, Ongole, Ravikiran, Taybos, George, Mackey, Regina, Rego, Renata, Camilotti, Renata, Ferrari, Renata, Junior, Renato, Bensadoun, Rene-Jean, Logan, Richard, Sales, Roberta, Zanicotti, Roberta, Tunes, Roberta, Mauceri, Rodolfo, Feitoza, Rosiene, Ruddy, Kathryn, Rybczyk, Cynthia, Trager, Stephanie, Mitsunaga, Sachiyo, Gunathilake, Sahani, Saini, Rajan, Salvestrini, Viola, Mukhopadhyay, Sandip, Angeloz, Sandrina, Sankar S, Pramod, Barbosa, Luciana S Barbosa, Volkova, Elena, Elad, Sharon, Cantoreggi, Sergio, Gordon, Sharon, Brown, Shelly, Janine Tam, Shu Yie, Faleiro, Sibelle, da Silva, Silmara, de Oliveira, Silvia, Jensen, Siri Beier, Skrinjar, Ivana, Beaumont, Sophie, Sperandio, Felipe, Reese, Sandra, Roser, Steven, Seo, Sachiko, van Leeuwen, Stephanie, Sonis, Stephen, Bernard, Stephen, Samuel, Stephen Rajan, Taylor, Stuart, Maitra, Suranjan, Skulski, Susanne, Carlisle, Suzanne, Avon, Sylvie Louise, Yokota, Tomoya, Yurikusa, Takashi, Polvora, Tabata Santos, Kelock, Tabitha, Fernandes, Tauana, Wain, Taylor, Brown, Timothy, Tetsuhito konishi, Ferreira, Thalyta Amanda, Kataoka, Tomoko, Kelly, Thomas, Mori, Takehiko, Higuchi, Tomoko, Saeki, Toshiaki, Tsoukalas, Nikolaos, De Vandeul, Typhaine Maupoint, Usubuchi, Masatoshi, Lacerda, Vanessa, Tilly, Vanessa, Vigarios, Emmanuelle, Villa, Alessandro, Torregrossa, Vinicius, Selvaraj, Vinodh Kumar, Sarmento, Viviane, Heng, Vivien, Gomes-Silva, Wagner, Kandwal, Abhishek, Wilberg, Petter, Miranda e Silva, Wanessa, I'zzah Wan Mohamad Zain, Wan Nor, Park, Wonse, Tissing, Wim, Soga, Yoshihiko, Van Sebille, Bella, Matsuda, Yuhei, Zadik, Yehuda, Cao, Katrina, Cheung, Yin Ting, Fregnani, Eduardo Rodrigues, Van Sebille, Ysabella, Kauark-Fontes, Elisa, McCurdy-Franks, Emma, Finkelstein, Joel, McCarvell, Victoria, Amaral Mendes, Rui, Speksnijder, Caroline Margina, and Wardill, Hannah Rose
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- 2024
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31. Potential water reuse pathways from a life cycle analysis perspective in the poultry industry
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Harasztiné Hargitai, Réka, Sebestyén, Viktor, and Somogyi, Viola
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- 2024
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32. Regime shift in microalgal dynamics: Impact of water level changes on planktonic and benthic algal biomass
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Somogyi, Boglárka, Li, Huan, Tapolczai, Kálmán, Kovács, Attila W., G.-Tóth, László, Horváth, Hajnalka, Krassován, Krisztina, Fodor-Kardos, Andrea, and Vörös, Lajos
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- 2024
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33. A novel and sustainable composite of L@PSAC for superior removal of pharmaceuticals from different water matrices: Production, characterization, and application
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Al-sareji, Osamah J., Al-Samarrai, Shatha Y., Grmasha, Ruqayah Ali, Meiczinger, Mónika, Al-Juboori, Raed A., Jakab, Miklós, Somogyi, Viola, Miskolczi, Norbert, and Hashim, Khalid S.
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- 2024
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34. Activated carbon and their nanocomposites derived from vegetable and fruit residues for water treatment
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Thamer, A.A., Mustafa, A., Bashar, H.Q., Van, Bao, Le, Phuoc-Cuong, Jakab, Miklós, Rashed, T.R., Kułacz, Karol, Hathal, MustafaM., Somogyi, Viola, and Nguyen, D. Duc
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- 2024
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35. Concurrent inhibition of ALK and SRC kinases disrupts the ALK lung tumor cell proteome
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Diaz-Jimenez, Alberto, Ramos, Maria, Helm, Barbara, Chocarro, Sara, Frey, Dario Lucas, Agrawal, Shubham, Somogyi, Kalman, Klingmüller, Ursula, Lu, Junyan, and Sotillo, Rocio
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- 2024
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36. Cognitive outcomes from the randomised, active-controlled Ketamine for Adult Depression Study (KADS)
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Martin, Donel M., Harvey, Anna J., Baune, Bernard, Berk, Michael, Carter, Gregory L., Dong, Vanessa, Glozier, Nick, Glue, Paul, Hood, Sean, Hadzi-Pavlovic, Dusan, Hackett, Maree, Mills, Natalie, Sarma, Shanthi, Somogyi, Andrew, Rodgers, Anthony, and Loo, Colleen K.
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- 2024
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37. Comparing DSM-5 pathological personality traits in eating disorder patients and healthy control subjects using PID-5: results of a pilot study
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J. Biliczki, J. Bognár, D. B. Pólya, S. Somogyi, S. Sutori, X. Gonda, S. Hamvas, and J. Réthelyi
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Psychiatry ,RC435-571 - Abstract
Introduction The presence of eating disorders is often associated with serious physical complications, self-destruction, and suicidal tendencies. Furthermore, eating disorders may often present as a symptom of or in comorbidity with personality disorders. In order to treat eating disorder patients successfully we need a more complex and individual approach taking into consideration the specific personality dysfunctions and traits present in the patient underlying symptomatic manifestations. Recently a paradigm shift in conceptualisation of personality disorders led to the introduction of a dimensional concept focusing on severity of dysfunction in both ICD-11 and DSM-5 in its Alternative Model for Personality Disorders (AMPD). IN addition, DSM-5 as part of AMPD also considers the presence of 5 domains of pathological personality traits including 25 facets. This more complex mapping of personality could aid understanding personality contributors to psychopathology not only in personality disorders and could aid treatment by providing targets for psychotherapy. Objectives Our aim was to compare pathological personality traits according to DSM-5 AMPD in eating disorder patients, and matched healthy control subjects. Methods We are launching a large project focusing on personality disorders. For this analysis we used the adult form of PID-5 to assess pathological personality traits along 5 domains and 25 facets in eating disorder patients and psychiatrically healthy controls. Data were analyzed with the Mann-Whitney test using R. Results Preliminary results of a pilot analysis in 14 eating disorder patients and matched psychiatrically health controls are shown. Comparing the data of the two groups, a significant difference was observed in several personality facets, including Anxiousness, Deceitfulness, Grandiosity, Impulsivity, Manipulativeness, Perceptual dysregulation, Rigid perfectionism, Submissiveness, and Unusual beliefs. These differences in the above facets reflect differences in the two groups in all pathological personality domains including Anhedonia, Negative affect, Antagonism, Disinhibition, and Psychoticism. Conclusions Our results show complex differences between eating disorder patients and healthy control subjects in several facets, pointing to a unique pattern and the affectedness of all pathological personality domains. Such results could possibly add to identifying personality trait targets for psychotherapy in eating disorders besides increasing our understanding on the etiopsychopathology of this serious psychiatric illness. Our study is ongoing, but more complex analyses involving further measures and variables in larger samples bring the hope for increasing effectiveness of treatment for anorexia. Disclosure of Interest None Declared
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- 2024
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38. Impulsivity profile analysis and it’s potential role in the differential diagnostics of adult Attention Deficit Hyperactivity Disorder and Borderline Personality Disorder
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E. Kenézlői, S. Somogyi, L. Balogh, E. Lévay, B. Bajzát, Z. Halmai, Z. S. Unoka, and J. Réthelyi
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Psychiatry ,RC435-571 - Abstract
Introduction Impulsivity is a complex construct, having at least three factors: 1) impulsivity as a personality trait, 2) ismpulsive action – waiting and stopping impulsivity and 3) choice impulsivity. Impulsive symptoms are present in Attention Deficit Hyperactivity Disorder (ADHD) and Borderline Personality Disorder (BPD) as well, eventhough impulsvity profile significantly differs. Objectives Our aim is to describe the impulsivity profile in adult ADHD (aADHD) and BPD in comparison with the control group, and describe a characteristic pattern, which associates with these disorders. Methods aADHD (n=100) and BPD Patients (n=63) were included, based on DSM-5 diagnostic criteria. Healthy control subjects (n=100) were screened using the Derogatis Symptom Checklist (SCL-90). Comorbid psychiatric disorders were assessed by structured clinical interviews and those who have both aADHD and BPD were excluded from the study. Participants were further investigated with online questionnaires: e.g. Barratt Impulsiveness Scale (BIS-11) Difficulties in Emotion Regulation Scale (DERS) and neuropsychological tests, like CANTAB Rapid Visual Processing, Stop Signal Task, and the Rogers’ decision-making test. Results Based ont the BIS-11 results, significantly higher attentional impulsivity was present in adult ADHD compared to BPD (p
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- 2024
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39. Age-Based Incidence of Dens Fracture Has Unimodal Distribution Rather Than Commonly Claimed Bimodal Distribution
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Rita Somogyi, BA, Spencer Smith, BS, Jonathan Kark, MD, Won Hyung A. Ryu, MD, and Jung Yoo, MD
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Orthopedic surgery ,RD701-811 - Abstract
Background:. Type-II dens fractures have long been described in the literature as occurring in a bimodal distribution, peaking in young adulthood as well as in older adulthood; however, the origin of this claim is unclear. The primary goal of this study was to examine the incidence of type-II dens fractures and assess for bimodality. Methods:. This is a retrospective cross-sectional review of the National Trauma Data Bank (NTDB) records on traumatic type-II dens fractures between October 2015 and December 2016. Rates were obtained from the NTDB, and the incidence per 100,000 was ascertained by utilizing U.S. Census data from 2016. Subgroupings by gender and Black or White race were also examined. Results:. Dens fractures occur unimodally, peaking around 89 years of age overall, skewed left by high rates in older White adults. The Black subgroup demonstrated trimodality, with the fracture incidence peaking at 25, 62, and 82 years of age. Rates among Black and White patients were similar until age 65, after which dens fractures occurred disproportionately in White patients. Fractures prior to age 75 occurred predominantly in men. Conclusions:. The evidence derived in this study challenges the common belief that type-II dens fractures occur bimodally across the entire population. However, there remains utility in considering younger and older patients as distinct groups for the purposes of management.
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- 2024
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40. Polysphaeroides filiformis, a proterozoic cyanobacterial microfossil and implications for cyanobacteria evolution
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Catherine F. Demoulin, Marie Catherine Sforna, Yannick J. Lara, Yohan Cornet, Andrea Somogyi, Kadda Medjoubi, Daniel Grolimund, Dario Ferreira Sanchez, Remi Tucoulou Tachoueres, Ahmed Addad, Alexandre Fadel, Philippe Compère, and Emmanuelle J. Javaux
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Natural sciences ,Evolutionary biology ,Paleobiology ,Science - Abstract
Summary: Deciphering the fossil record of cyanobacteria is crucial to understand their role in the chemical and biological evolution of the early Earth. They profoundly modified the redox conditions of early ecosystems more than 2.4 Ga ago, the age of the Great Oxidation Event (GOE), and provided the ancestor of the chloroplast by endosymbiosis, leading the diversification of photosynthetic eukaryotes. Here, we analyze the morphology, ultrastructure, chemical composition, and metals distribution of Polysphaeroides filiformis from the 1040–1006 Ma Mbuji-Mayi Supergroup (DR Congo). We evidence trilaminar and bilayered ultrastructures for the sheath and the cell wall, respectively, and the preservation of Ni-tetrapyrrole moieties derived from chlorophyll in intracellular inclusions. This approach allows an unambiguous interpretation of P. filiformis as a branched and multiseriate photosynthetic cyanobacterium belonging to the family of Stigonemataceae. It also provides a possible minimum age for the emergence of multiseriate true branching nitrogen-fixing and probably heterocytous cyanobacteria.
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- 2024
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41. Leveraging code-free deep learning for pill recognition in clinical settings: A multicenter, real-world study of performance across multiple platforms
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Ashraf, Amir Reza, Somogyi-Végh, Anna, Merczel, Sára, Gyimesi, Nóra, and Fittler, András
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- 2024
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42. A sustainable nano-hybrid system of laccase@M-MWCNTs for multifunctional PAHs and PhACs removal from water, wastewater, and lake water
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Grmasha, Ruqayah Ali, Al-sareji, Osamah J., Meiczinger, Mónika, Stenger-Kovács, Csilla, Al-Juboori, Raed A., Jakab, Miklós, Lengyel, Edina, Somogyi, Viola, Khan, Mohammad Amir, and Hashim, Khalid S.
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- 2024
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43. Half-life of serum anti-Müllerian hormone and changes after gonadectomy in adult female and male dogs with normal and abnormal gonads
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Balogh, Orsolya, Szilágyi, Eszter, Balogh, Nándor, Somogyi, Zoltán, and Müller, Linda
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- 2024
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44. A sustainable and highly efficient fossil-free carbon from olive stones for emerging contaminants removal from different water matrices
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Al-sareji, Osamah J., Grmasha, Ruqayah Ali, Meiczinger, Mónika, Al-Juboori, Raed A., Somogyi, Viola, Stenger-Kovács, Csilla, and Hashim, Khalid S.
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- 2024
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45. Polysphaeroides filiformis, a proterozoic cyanobacterial microfossil and implications for cyanobacteria evolution
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Demoulin, Catherine F., Sforna, Marie Catherine, Lara, Yannick J., Cornet, Yohan, Somogyi, Andrea, Medjoubi, Kadda, Grolimund, Daniel, Sanchez, Dario Ferreira, Tachoueres, Remi Tucoulou, Addad, Ahmed, Fadel, Alexandre, Compère, Philippe, and Javaux, Emmanuelle J.
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- 2024
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46. Effect of Sterilization Methods on Chemical and Physical-Mechanical Properties of Cotton Compresses
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Maja Somogyi Škoc, Jana Juran, and Iva Rezić
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medical textiles ,sterilization ,steam sterilization ,sterilization with ethylene oxide ,cotton compresses ,textile testing ,Organic chemistry ,QD241-441 - Abstract
The aim of this work was to determine the changes in the chemical and physical-mechanical properties of gauze compresses under the influence of various sterilizations. Gauze compresses are made of cotton; therefore, all methods used focused on cotton. The methods used to test possible damage to cotton materials (pH value (pH paper, KI starch paper), yellowing test, Fehling reaction, reaction to the formation of Turnbull blue (Berlin blue), microscopic staining with methylene blue and swelling reaction with Na-zincate) did not show that the sterilizations affected the cotton compresses. The morphological characteristics were examined with a scanning electron microscope (SEM). The SEM images showed that there were no morphological changes in the cotton fibers. FTIR-ATR spectroscopy revealed that the sterilization processes did not alter the characteristic bands of the cotton. The length of the macromolecules was increased (DP), showing that the sterilization processes had affected the cotton. The results of the wet strength test followed. The samples showed values below 100%, with the exception of two samples. It is known from theory that the relative wet strength is less than 100% when the material is damaged. The t-test performed on the strength results showed that the p-value was greater than 0.05 for all samples tested, with the exception of one sample. The degree of swelling capacity was determined, with non-sterilized samples having the highest capacity, followed by samples sterilized with ethylene oxide and then samples sterilized by steam sterilization. The results obtained are a contribution to the innovation of the topic of this work and a scientific confirmation for manufacturers and anyone interested in the influence of the sterilization process on natural fibers (cotton).
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- 2024
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47. Survey of Potential Drug Interactions, Use of Non-Medical Health Products, and Immunization Status among Patients Receiving Targeted Therapies
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Réka Rajj, Nóra Schaadt, Katalin Bezsila, Orsolya Balázs, Marcell B. Jancsó, Milán Auer, Dániel B. Kiss, András Fittler, Anna Somogyi-Végh, István G. Télessy, Lajos Botz, and Róbert Gy. Vida
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targeted therapy ,biological therapy ,chronic immunological disorders ,clinical pharmacy service ,dietary supplements ,drug interactions ,Medicine ,Pharmacy and materia medica ,RS1-441 - Abstract
In recent years, several changes have occurred in the management of chronic immunological conditions with the emerging use of targeted therapies. This two-phase cross-sectional study was conducted through structured in-person interviews in 2018–2019 and 2022. Additional data sources included ambulatory medical records and the itemized reimbursement reporting interface of the National Health Insurance Fund. Drug interactions were analyzed using the UpToDate Lexicomp, Medscape drug interaction checker, and Drugs.com databases. The chi-square test was used, and odds ratios (ORs) were calculated. In total, 185 patients participated. In 53% of patients (n = 53), a serious drug–drug interaction (DDI) was identified (mean number: 1.07 ± 1.43, 0–7), whereas this value was 38% (n = 38) for potential drug–supplement interactions (mean number: 0.58 ± 0.85, 0–3) and 47% (n = 47) for potential targeted drug interactions (0.72 ± 0.97, 0–5) in 2018. In 2022, 78% of patients (n = 66) were identified as having a serious DDI (mean number: 2.27 ± 2.69, 0–19), 66% (n = 56) had a potential drug–supplement interaction (mean number: 2.33 ± 2.69, 0–13), and 79% (n = 67) had a potential targeted drug interactions (1.35 ± 1.04, 0–5). Older age (>60 years; OR: 2.062), female sex (OR: 3.387), and polypharmacy (OR: 5.276) were identified as the main risk factors. Screening methods and drug interaction databases do not keep pace with the emergence of new therapeutics.
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- 2024
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48. Synthesis and Characterization of ZnO and TiO2 Hybrid Coatings for Textile UV Anti-Aging Protection
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Maja Somogyi Škoc, Jelena Macan, Suzana Jakovljević, and Iva Rezić
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sol–gel process ,ZnO ,TiO2 ,modification ,materials ,anti-aging ,Organic chemistry ,QD241-441 - Abstract
The aim of this study was to prepare and characterize thin hybrid films on polyurethane-coated knitted fabrics and to achieve satisfactory color fastness to artificial light. Sol–gel-derived hybrid thin films were deposited via the dip-coating of 3-glycidoxypropiltrimethoxysilane. Titanium dioxide (TiO2) and zinc oxide (ZnO) nanopowders were added to compensate for the insufficient aging resistance, which manifests itself in low color fastness and is one of the most frequent complaints from manufacturers of coated marine fabrics (yachts, boats, etc.). The optimum processing conditions were determined by varying the concentration of precursors and auxiliaries, the mass concentration of TiO2 and ZnO nanopowders, the drawing speed, and the methods and process of fabric treatment. The hybrid films were also characterized using scanning electron microscopy and Fourier transform infrared spectroscopy with attenuated total internal reflection, while Spectraflash SF 300 investigated color fastness. After 300 h of exposure in a xenon chamber, the thin hybrid films showed good color fastness and good resistance to washing cycles. The sol–gel treatment proved to be a successful answer to the manufacturers’ need for the post-treatment of polyurethane-coated knitted fabrics against UV radiation for use in the marine sector (yachts, speedboats, etc.).
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- 2024
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49. Comparison of the Bactericidal Effect of Ultrasonic and Heat Combined with Ultrasonic Treatments on Egg Liquids and Additional Analysis of Their Effect by NIR Spectral Analysis
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Dávid Nagy, Tamás Zsom, Andrea Taczman-Brückner, Tamás Somogyi, Viktória Zsom-Muha, and József Felföldi
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egg yolk ,egg white ,whole egg ,food safety ,E. coli ,disinfection ,Chemical technology ,TP1-1185 - Abstract
Eggs are a valuable source of nutrients, but they represent a food safety risk due to the presence of microbes. In this work, three types of egg liquids (albumen, yolk and whole egg) previously contaminated with E. coli were treated with ultrasound (US) and a combination of ultrasound and low (55 °C) temperature (US+H). The US treatment parameters were 20 and 40 kHz and 180 and 300 W power and a 30, 45 or 60 min treatment time. The ultrasonic treatment alone resulted in a reduction in the microbial count of less than 1 log CFU, while the US+H treatment resulted in a reduction in CFU counts to below detectable levels in all three egg liquids. Heat treatment and ultrasound treatment had a synergistic effect on E. coli reduction. For all measurements, except for the whole egg samples treated with US, the 20 kHz treated samples showed a significantly (>90% probability level) lower bactericidal effect than the 40 kHz treated samples. PCA and aquaphotometric analysis of NIR spectra showed significant differences between the heat-treated groups’ (H and US+H) and the non-heat-treated groups’ (US and control) NIR spectra. LDA results show that heat-treated groups are distinguishable from non-heat-treated groups (for albumen 91% and for egg yolk and whole egg 100%).
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- 2024
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50. Age-Based Incidence of Dens Fracture Has Unimodal Distribution Rather Than Commonly Claimed Bimodal Distribution
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Somogyi, Rita, Smith, Spencer, Kark, Jonathan, Ryu, Won Hyung A., and Yoo, Jung
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- 2024
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