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This study aimed to investigate the influence of tooth shade and skin tone on smile attractiveness among native South Indians. The primary research question was whether there is a significant relationship between these variables and perceived smile attractiveness. A web-based cross-sectional survey was conducted with approval from the Institutional Review Board of (Thai Moogambigai Dental College and Hospital, Chennai). Standardized smile photographs of two South Indian models (one male and one female) were digitally modified to display four different tooth shades and four different skin tones, resulting in 32 images. These images were incorporated into a Google Form along with a questionnaire and a Visual Analog Scale (VAS) for attractiveness rating. The survey was distributed to 1200 participants, including both dental professionals and the general population, with 1000 valid responses recorded. Statistical analysis was performed using IBM SPSS Statistics, employing parametric tests to evaluate the data. The study found that lighter tooth shades were consistently rated higher in attractiveness for both genders. Lighter tooth shades such as FS1T1 and FS2T1 scored means of 6.88 and 7.27 respectively for females, while darker shades like FS1T4 scored lower with a mean of 4.95. Similarly, males showed a preference for lighter tooth shades with MS1T1 and MS2T1 scoring means of 5.57 and 5.78 respectively compared to darker shades like MS1T4 with a mean of 3.63. Significant differences were noted across age groups and genders, with younger participants and females showing a stronger preference for lighter tooth shades. The study concludes that both tooth shade and skin tone significantly influence smile attractiveness, with a clear preference for lighter tooth shades among the surveyed population. These findings suggest the importance of considering these factors in aesthetic dental treatments to enhance patient satisfaction and achieve optimal results. The results underscore the necessity for dental practitioners to take into account both tooth shade and skin tone when planning aesthetic dental treatments. This approach will help in achieving a more harmonious and natural appearance, ultimately improving patient satisfaction with the treatment outcomes. Future research should continue to explore the cultural and individual factors that contribute to these preferences in dental aesthetics. [ABSTRACT FROM AUTHOR]

Objectives: This study aimed to investigate the influence of tooth shade and skin tone on smile attractiveness among native South Indians. The primary research question was whether there is a significant relationship between these variables and perceived smile attractiveness. Materials and methods: A web-based cross-sectional survey was conducted with approval from the Institutional Review Board of (Thai Moogambigai Dental College and Hospital, Chennai). Standardized smile photographs of two South Indian models (one male and one female) were digitally modified to display four different tooth shades and four different skin tones, resulting in 32 images. These images were incorporated into a Google Form along with a questionnaire and a Visual Analog Scale (VAS) for attractiveness rating. The survey was distributed to 1200 participants, including both dental professionals and the general population, with 1000 valid responses recorded. Statistical analysis was performed using IBM SPSS Statistics, employing parametric tests to evaluate the data. Results: The study found that lighter tooth shades were consistently rated higher in attractiveness for both genders. Lighter tooth shades such as FS1T1 and FS2T1 scored means of 6.88 and 7.27 respectively for females, while darker shades like FS1T4 scored lower with a mean of 4.95. Similarly, males showed a preference for lighter tooth shades with MS1T1 and MS2T1 scoring means of 5.57 and 5.78 respectively compared to darker shades like MS1T4 with a mean of 3.63. Significant differences were noted across age groups and genders, with younger participants and females showing a stronger preference for lighter tooth shades. Conclusions: The study concludes that both tooth shade and skin tone significantly influence smile attractiveness, with a clear preference for lighter tooth shades among the surveyed population. These findings suggest the importance of considering these factors in aesthetic dental treatments to enhance patient satisfaction and achieve optimal results. Clinical relevance: The results underscore the necessity for dental practitioners to take into account both tooth shade and skin tone when planning aesthetic dental treatments. This approach will help in achieving a more harmonious and natural appearance, ultimately improving patient satisfaction with the treatment outcomes. Future research should continue to explore the cultural and individual factors that contribute to these preferences in dental aesthetics.

Background: Insulin resistance plays a pivotal role in the progression of Type 2 Diabetes Mellitus (T2DM), and the triglyceride to high-density lipoprotein cholesterol (TAG/HDL) ratio has been proposed as a marker for both insulin resistance and cardiovascular risk. This study aims to assess the TAG/HDL ratio as a biomarker for insulin resistance in male T2DM patients from the South Indian population. Methods: A cross-sectional study was conducted with 30 male T2DM patients aged 30-60 years. Anthropometric measurements, lipid profiles, fasting insulin, fasting glucose, and HbA1c were recorded. The TAG/HDL ratio was calculated and correlated with insulin resistance using Pearson's correlation coefficient. Results: Elevated triglyceride levels were strongly associated with insulin resistance, showing a significant correlation (p = 0.0021). However, the TAG/HDL ratio did not demonstrate a significant correlation with insulin resistance in this cohort (p = 0.1882). These findings suggest that while the TAG/HDL ratio may not be a reliable marker for insulin resistance in this population, elevated triglycerides alone are strong indicators of metabolic dysfunction. Conclusion: The TAG/HDL ratio did not serve as a significant marker for insulin resistance in male T2DM patients. However, elevated triglycerides should be monitored closely, and a comprehensive lipid profile, along with thyroid function assessments, may provide better insight into managing insulin resistance in T2DM patients. [ABSTRACT FROM AUTHOR]

Background: Proximal femur analysis plays a vital role in orthopedic surgery, implant design, fracture care, and research. Studying this complex bone helps surgeons select the right implants, plan fracture treatment, and understand bone strength. This growing field improves clinical outcomes and enhances scientific knowledge. Our study analyzes the morphometry of proximal femur, particularly the head and neck, to further explore its implications. Aims and Objectives: To study the morphometric measurements of the proximal end of the femur quantitatively in the South Indian population from the dry femora available in the Department of Anatomy, Government Medical College, Kottayam. Materials and Methods: This cross-sectional study was conducted in 101 dry femora available in the Department of Anatomy, Government Medical College, Kottayam. The measurements were taken with digital Vernier calipers and a goniometer. All continuous variables were expressed as mean with standard deviation. Statistical differences between the right and left sides were analyzed with Student’s independent sample t-test (for parametric variables) and Mann–Whitney U test (for non-parametric variables). Results: The mean vertical and anteroposterior diameter of the femoral head, superior and inferior length of the femoral head, the anteroposterior and vertical diameter of the femoral neck, superior and inferior lengths of the femoral neck, neck-shaft angle, and intertrochanteric length were 39.61±3.29 mm, 40.17±3.14 mm, 33.01±3.6 mm, 23.88±4.32 mm, 24.22±3 mm, 29.59±3 mm, 21.75±3.81 mm, 32.03±5.58 mm, 124.11±6.37, 60.31±7.33 mm, respectively. There was a statistically significant difference in the mean of neck anteroposterior diameter and neck-shaft angle between the right and left sides where the left side had the higher value. Conclusion: Notable skeletal metric variations exist amidst different populations. Proximal femoral dimensions can be acquired through either manual means or radiological information. These measurements can be used in designing orthopedic implants for the South Indian population.

Background: The complex framework of the human foot enables movement and weight support. The os peroneum (OP) is a sesamoid bone located in the tendon of peroneus longus. Though tiny, it plays crucial roles in foot movement and arch stability injuries to the tendon are significant, and the OP itself can fracture, dislocate, or impinge. Its presence, size, and even histological type influence the proper functioning of the foot. Studying this sesamoid bone, with its variable prevalence and morphology, can fill gaps in foot and ankle pathology research. Aims and Objectives: To analyze the prevalence, morphology, morphometry, and histology of OP in human adult cadavers in the South Indian population. Materials and Methods: Forty-two formalin-fixed human adult cadaveric free lower limbs were selected and studied from the Department of Anatomy, Pushpagiri Institute of Medical Sciences and Research Centre, Tiruvalla, Kerala. The prevalence of OP in peroneus longus tendons (PLT) and its various configurations were carefully observed, along with their histological types, and then statistical analysis of the data was done using SPSS version 20. Results: Thirty-nine out of the forty-two free lower limbs showed the presence of an OP bearing a smooth oval facet, except for one OP with a round facet. All OP were invariably present in the tunnel for PLT on the plantar surface of the cuboid bone. Three different histological types of this tissue were observed, i.e., osseous, cartilaginous, and fibrous. Conclusion: The present study has attempted to fill the gap in the research data regarding OP in the adult South Indian population. In addition, the knowledge of OP and its configuration in PLT could provide a better radiological and clinical approach to mid- and fore-foot pathologies.

Background: Proximal femur analysis plays a vital role in orthopedic surgery, implant design, fracture care, and research. Studying this complex bone helps surgeons select the right implants, plan fracture treatment, and understand bone strength. This growing field improves clinical outcomes and enhances scientific knowledge. Our study analyzes the morphometry of proximal femur, particularly the head and neck, to further explore its implications. Aims and Objectives: To study the morphometric measurements of the proximal end of the femur quantitatively in the South Indian population from the dry femora available in the Department of Anatomy, Government Medical College, Kottayam. Materials and Methods: This cross-sectional study was conducted in 101 dry femora available in the Department of Anatomy, Government Medical College, Kottayam. The measurements were taken with digital Vernier calipers and a goniometer. All continuous variables were expressed as mean with standard deviation. Statistical differences between the right and left sides were analyzed with Student’s independent sample t-test (for parametric variables) and Mann–Whitney U test (for non-parametric variables). Results: The mean vertical and anteroposterior diameter of the femoral head, superior and inferior length of the femoral head, the anteroposterior and vertical diameter of the femoral neck, superior and inferior lengths of the femoral neck, neck-shaft angle, and intertrochanteric length were 39.61±3.29 mm, 40.17±3.14 mm, 33.01±3.6 mm, 23.88±4.32 mm, 24.22±3 mm, 29.59±3 mm, 21.75±3.81 mm, 32.03±5.58 mm, 124.11±6.37, 60.31±7.33 mm, respectively. There was a statistically significant difference in the mean of neck anteroposterior diameter and neck-shaft angle between the right and left sides where the left side had the higher value. Conclusion: Notable skeletal metric variations exist amidst different populations. Proximal femoral dimensions can be acquired through either manual means or radiological information. These measurements can be used in designing orthopedic implants for the South Indian population. [ABSTRACT FROM AUTHOR]

Background: The complex framework of the human foot enables movement and weight support. The os peroneum (OP) is a sesamoid bone located in the tendon of peroneus longus. Though tiny, it plays crucial roles in foot movement and arch stability injuries to the tendon are significant, and the OP itself can fracture, dislocate, or impinge. Its presence, size, and even histological type influence the proper functioning of the foot. Studying this sesamoid bone, with its variable prevalence and morphology, can fill gaps in foot and ankle pathology research. Aims and Objectives: To analyze the prevalence, morphology, morphometry, and histology of OP in human adult cadavers in the South Indian population. Materials and Methods: Forty-two formalin-fixed human adult cadaveric free lower limbs were selected and studied from the Department of Anatomy, Pushpagiri Institute of Medical Sciences and Research Centre, Tiruvalla, Kerala. The prevalence of OP in peroneus longus tendons (PLT) and its various configurations were carefully observed, along with their histological types, and then statistical analysis of the data was done using SPSS version 20. Results: Thirty-nine out of the forty-two free lower limbs showed the presence of an OP bearing a smooth oval facet, except for one OP with a round facet. All OP were invariably present in the tunnel for PLT on the plantar surface of the cuboid bone. Three different histological types of this tissue were observed, i.e., osseous, cartilaginous, and fibrous. Conclusion: The present study has attempted to fill the gap in the research data regarding OP in the adult South Indian population. In addition, the knowledge of OP and its configuration in PLT could provide a better radiological and clinical approach to mid- and fore-foot pathologies. [ABSTRACT FROM AUTHOR]

Introduction The pericardial fat pad, located anteriorly to the heart between the pericardium and myocardium, has garnered significant interest in cardiovascular research due to its potential role in the pathophysiology of various cardiac conditions. Despite its proximity to the myocardium, it is distinct from the epicardial fat depot found between the myocardium and the visceral layer of the pericardium. Studies have shown that excess pericardial fat is associated with an increased risk of heart failure and other cardiovascular diseases. Non-contrast computed tomography (CT) is a reliable, non-invasive method for assessing pericardial fat pad thickness, offering less radiation exposure compared to other imaging modalities. Establishing standardized measurements for pericardial fat pad thickness is essential, particularly for the South Indian population, which may exhibit unique genetic, dietary, and lifestyle influences on these measurements. Materials and methods A cross-sectional study was conducted on 300 participants from South India, stratified into three age groups: 18-35, 36-50, and 51-70 years, with body weights ranging from 45 kg to 120 kg. Participants were recruited from outpatient departments and community outreach programs, ensuring equal representation from each age group. Non-contrast CT imaging was performed using a Siemens Somatom goTop 128 Slice CT scanner to measure pericardial fat pad thickness and correlate it with age, gender, body weight, and body mass index. Exclusion criteria included diagnosed cardiac or pericardial diseases, prior chest surgery or trauma, pregnancy, and contraindications to CT scans. Ethical approval was obtained, and informed consent was collected from all participants. Data analysis was performed using SPSS software, employing descriptive statistics, ANOVA, t-tests, and Pearson's correlation. Results The study included 300 participants, with an equal gender distribution of 150 males and 150 females. Pericardial fat pad thickness increased with age, averaging 4.2 mm in the 18-35 age group, 5.1 mm in the 36-50 age group, and 6.4 mm in the 51-70 age group. Males exhibited a higher average thickness (5.6 mm) compared to females (5.0 mm). Body weight also showed a positive correlation with pericardial fat pad thickness, with mean values increasing from 4.5 mm in the 45-60 kg range to 6.7 mm in the 106-120 kg range. Statistical analysis confirmed significant differences in pericardial fat pad thickness across age groups, genders, and weight categories, emphasizing the importance of these factors in assessing cardiovascular risk. Conclusion This study provides a benchmark for pericardial fat pad thickness in the Kancheepuram Population of South India, highlighting its correlation with age, gender, body weight, and body mass index. The findings underscore the significance of non-invasive CT imaging in evaluating cardiovascular risk factors. Further research should focus on longitudinal studies and advanced imaging techniques to enhance the diagnostic accuracy and clinical relevance of pericardial fat pad measurements. The established reference values can aid clinicians in identifying individuals at higher risk for cardiovascular diseases, facilitating early intervention and management., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Review Board (IRB) of Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University issued approval SMCH/SIMATS/2023-CT04. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Ramakrishnan et al.)