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Your search keyword '"Szeto Ignatius Man-Yau"' showing total 3 results
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2. Effect of Different Ratios of α-Lactalbumin to β-Casein in Infant Formula on True Ileal Digestibility and Intestinal Morphology of Suckling Piglets

Author

Wu, Yuliang, Yan, Yalu, Xiong, Xia, Li, Rui, Duan, Sufang, Tang, Mengxuan, Szeto, Ignatius Man-Yau, Liu, Hongnan, Hodgkinson, Suzanne M., Moughan, Paul J., Wescombe, Philip, Wang, Jianwu, and Yin, Yulong

Abstract

Breast milk (BM) is the optimal nutrition source for infants, providing highly digestible proteins. In contrast, the digestibility of proteins in infant formula (IF) varies, influenced by differences in proteins such as α-lactalbumin (α-La) and β-casein (β-CN). This study aimed to evaluate the true ileal digestibility (TID) of amino acids (AAs) in BM and IF with varying α-La and β-CN contents using neonatal piglets. Twenty-four 11-day-old piglets (4 groups; 6 replicates/group) received either a nitrogen-free diet, IF (high infant formula (HIF) with 1.74 g/100 α-La and 2.3 g/100 β-CN; low infant formula (LIF) with 1.07 g/100 α-La and 1.85 g/100 β-CN), or BM (1.82 g/100 α-La and 3.05 g/100 β-CN) for 7 days after 3 prefeed days. IF had higher concentrations of nitrogen, serine, threonine, and proline than BM. Glutamic acid was the most abundant AA in IF and BM, while methionine in BM and LIF or tryptophan in HIF was the least. BM showed the highest TID of AAs, with the LIF had the lowest. The HIF group’s TID for AAs, especially tryptophan, was similar to BM and significantly better than LIF. These results suggest that adjusting the α-La and β-CN ratio in IF can improve AA digestibility, approaching BM levels.

Published
2025
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3. Global levels and variations of breast milk fatty acids and triacylglycerols: A systematic review and meta-analysis.

Author

Ni X, Zhang Z, Deng Z, Duan S, Szeto IM, He J, Li T, and Li J

Abstract

Understanding global temporal and spatial variations in breast milk composition is crucial for developing personalized infant nutrition strategies. This study analyzed 46,673 breast milk samples from 171 studies using a random-effects model to evaluate total fatty acids (TFA), sn-2 fatty acids (sn-2 FA), and triacylglycerols (TAG) across lactation stages, regions, and sample years. Results showed that saturated fatty acids (SFA) increased while unsaturated fatty acids (UFA) decreased with prolonged lactation, with corresponding changes in triacylglycerol profiles. Geographically, Africa had the highest SFA and lowest UFA, Asia had the highest PUFA, and Europe had the highest MUFA. Over time, SFA and SFA-dominant TAGs declined, while UFA and UFA-dominant TAGs rose. These variations reflect shifts in maternal diet, infant nutritional needs, and potential growth outcomes, highlighting the importance of monitoring breast milk lipids to optimize infant nutrition strategies., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2025. Published by Elsevier Ltd.)

Published
2025
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