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• A highly stable narrow linewidth erbium-doped fiber laser was proposed. • The self-injection locked mechanism was utilized in the ring-cavity fiber laser. • The cascaded Type Ⅱ fiber rings cavity filter was used to keep single-longitudinal-mode output. • The maximum wavelength drift was 0.0041 nm and the maximum peak power fluctuation was kept at a low level of 0.16 dB. • The minimum linewidth at a 0.002 s was 1.82 kHz. Narrow linewidth erbium-doped fiber lasers (EDFLs) hold in significant potential optical fiber sensing, wavelength multiplexing transmission, and optical fiber communication. However, many EDFLs produced outputs with linewidth in several kHz level. Therefore, a high optical signal-to-noise ratio (OSNR), narrow linewidth single-longitudinal-mode (SLM) EDFL was proposed and investigated in this work. The EDFL utilized a combination of compound-ring cavity filter and a self-injection locked mechanism to generate a stable SLM output with an OSNR greater than 72 dB. The maximum wavelength drift and maximum peak power fluctuation over 60 min were maintained at low values of 0.0041 nm and 0.16 dB. Moreover, a narrow linewidth of 1.82 kHz at a measuring time of 0.002 s was realized. Furthermore, the research also investigated output power variations with different pump powers, relaxation oscillation, and the dependence of output central wavelength on the axial strain. [ABSTRACT FROM AUTHOR]

• A highly stable single-longitudinal-mode erbium-doped fiber laser was proposed. • A novel mode-selection filter, composed of two Type-Ⅱ fiber rings and a 1.5 m SA was used to realize SLM output. • The maximum wavelength drift was not observed and the maximum peak power fluctuation was kept at a low level of 0.16 dB. • The minimum linewidth at an integration time of 0.005 s was 2.8809 kHz. Single-longitudinal-mode (SLM) fiber lasers have the advantages of stable output, long coherence length, and low noise. However, several fiber lasers still maintain multiple longitudinal mode outputs. Thus, a highly stable SLM erbium-doped fiber laser (EDFL) was proposed and investigated. The dual-ring compound cavity (DRCC) filter, composed of two Type-Ⅱ fiber rings, and a 1.5 m unpumped erbium-doped fiber (EDF) was used as a mode-selection filter. The mode-selection capability of the DRCC filter and unpumped EDF was investigated and discussed theoretically and experimentally. The proposed EDFL could generate stable SLM output with an optical signal-to-noise ratio of ∼ 64 dB over 60 min. The maximum wavelength drift was not observed on an optical spectrum analyzer and the maximum peak power fluctuation was kept at a low level of 0.16 dB. The output power variations with different pump powers, the relative intensity noise, the relaxation oscillation, and the linewidth at different integration times were investigated. Furthermore, the performance of the proposed EDFL acted as a strain sensor and temperature sensor with sensitivities of 1.0 pm/με and 11.4 pm/℃ were also discussed. [ABSTRACT FROM AUTHOR]

N6-methyladenosine (m6A) stands as the most prevalent modified form of RNA in eukaryotes, pivotal in various biological processes such as regulating RNA stability, translation, and transcription. All members within the YT521-B homology (YTH) gene family are categorized as m6A reading proteins, capable of identifying and binding m6A modifications on RNA, thereby regulating RNA metabolism and functioning across diverse physiological processes. YTH domain-containing 2 (YTHDC2), identified as the latest member of the YTH family, has only recently started to emerge for its biological function. Numerous studies have underscored the significance of YTHDC2 in human physiology, highlighting its involvement in both tumor progression and non-tumor diseases. Consequently, this review aims to further elucidate the pathological mechanisms of YTHDC2 by summarizing its functions and roles in tumors and other diseases, with a particular focus on its downstream molecular targets and signaling pathways. [ABSTRACT FROM AUTHOR]

Purpose: Human-induced marine environmental noise, such as commercial shipping and seismic exploration, is concentrated in the low-frequency range. Meanwhile, low-frequency sound signals can achieve long-distance propagation in water. To meet the requirements of long-distance underwater detection and communication, this paper aims to propose an micro-electro-mechanical system (MEMS) flexible conformal hydrophone for low-frequency underwater acoustic signals. The substrate of the proposed hydrophone is polyimide, with silicon as the piezoresistive unit. Design/methodology/approach: This paper proposes a MEMS heterojunction integration process for preparing flexible conformal hydrophones. In addition, sensors prepared based on this process are non-contact flexible sensors that can detect weak signals or small deformations. Findings: The experimental results indicate that making devices with this process cannot only achieve heterogeneous integration of silicon film, metal wire and polyimide, but also allow for customized positions of the silicon film as needed. The success rate of silicon film transfer printing is over 95%. When a stress of 1 Pa is applied on the x-axis or y-axis, the maximum stress on Si as a pie-zoresistive material is above, and the average stress on the Si film is around. Originality/value: The flexible conformal vector hydrophone prepared by heterogeneous integration technology provides ideas for underwater acoustic communication and signal acquisition of biomimetic flexible robotic fish. [ABSTRACT FROM AUTHOR]