Search

In this work, the fractional Gross–Pitaevskii equation and fractional Radhakrishnan–Kundu Lakshmanan equation are investigated. A large number of new soliton solutions are obtained by implementing a simple and effective mathematical method, which is called the fractional unified solver method. Moreover, the 3D and 2D graphs are plotted to elaborate on the dynamic characteristics of these acquired solutions. [ABSTRACT FROM AUTHOR]

Under the current research, the local fractional (3+1)-dimensional modified Zakharov–Kuznetsov equation (MZKE) is explored. With the Mittag–Leffler function (MLF) defined on the Cantor sets (CS), four special functions, namely the SHχ(ℑχ), CHχ(ℑχ), SEχ(ℑχ) and CSχ(ℑχ) are extracted to construct an auxiliary function. Then the auxiliary function, along with Yang’s non-differentiable (ND) transformation, is manipulated to explore the ND exact solutions (ESs). By means of the proposed method, four different sets of the ND ESs are found in just one step. The nonlinear dynamics of the ND exact solutions on the CS are illustrated graphically. Furthermore, the ND exact solutions for χ =ln 2/ln3 and the classic exact solutions for χ = 1 are also compared and discussed in detail via the 2-D curves. The attained results reveal that the method is a simple but effective tool to deal with local fractional PDEs arising in physics and maths. [ABSTRACT FROM AUTHOR]

Total coronary atherosclerotic plaque activity across the entire coronary arterial tree is associated with patient-level clinical outcomes. We aimed to investigate whether vessel-level coronary atherosclerotic plaque activity is associated with vessel-level myocardial infarction. In this secondary analysis of an international multicenter study of patients with recent myocardial infarction and multivessel coronary artery disease, we assessed vessel-level coronary atherosclerotic plaque activity using coronary 18F-sodium fluoride positron emission tomography to identify vessel-level myocardial infarction. Increased 18F-sodium fluoride uptake was found in 679 of 2,094 coronary arteries and 414 of 691 patients. Myocardial infarction occurred in 24 (4%) vessels with increased coronary atherosclerotic plaque activity and in 25 (2%) vessels without increased coronary atherosclerotic plaque activity (HR: 2.08; 95% CI: 1.16-3.72; P = 0.013). This association was not demonstrable in those treated with coronary revascularization (HR: 1.02; 95% CI: 0.47-2.25) but was notable in untreated vessels (HR: 3.86; 95% CI: 1.63-9.10; P interaction = 0.024). Increased coronary atherosclerotic plaque activity in multiple coronary arteries was associated with heightened patient-level risk of cardiac death or myocardial infarction (HR: 2.43; 95% CI: 1.37-4.30; P = 0.002) as well as first (HR: 2.19; 95% CI: 1.18-4.06; P = 0.013) and total (HR: 2.50; 95% CI: 1.42-4.39; P = 0.002) myocardial infarctions. In patients with recent myocardial infarction and multivessel coronary artery disease, coronary atherosclerotic plaque activity prognosticates individual coronary arteries and patients at risk for myocardial infarction. [Display omitted] [ABSTRACT FROM AUTHOR]

Let ℒ 2 = (- Δ) 2 + V 2 be the Schrödinger-type operator on ℝ n ( n ≥ 5 ), let H ℒ 2 1 ⁢ (ℝ n) be the Hardy space related to ℒ 2 , and let BMO θ ⁢ (ρ) be the BMO-type space introduced by Bongioanni, Harboure and Salinas. In this paper, we investigate the boundedness of commutator [ b , T α , β , j ] , which is generated by the Riesz transform T α , β , j = V 2 ⁢ α ⁢ ∇ j ⁡ ℒ 2 - β , j = 1 , 2 , 3 , and b ∈ BMO θ ⁢ (ρ) . Here, 0 < α ≤ 1 - j 4 , j 4 < β ≤ 1 , β - α = j 4 , and the nonnegative potential V belongs to both the reverse Hölder class RH s with s ≥ n 2 and the Gaussian class associated with (- Δ) 2 . The L p boundedness of [ b , T α , β , j ] is obtained, and it is also shown that [ b , T α , β , j ] is bounded from H ℒ 2 1 ⁢ (ℝ n) to weak L 1 ⁢ (ℝ n) . [ABSTRACT FROM AUTHOR]

The current work is concerned with some novel solutions of the new extended (3 + 1)-dimensional Boiti–Leon–Manna–Pempinelli equation (BLMPE) that plays a key role in the incompressible fluid. The N-soliton solutions (NSSs) are extracted by virtue of the Hirota form which is developed using the Cole–Hopf transform. Based on the NSSs, we elaborate the resonance conditions of the soliton molecules and derive the soliton molecules of the 2-solitons, 3-solitons and 4-solitons on the (x, y)-, (x, z)- and (y, z)-planes. Additionally, we also explore some novel hybrid interaction solutions including the interaction between the soliton molecule and solitons and the interaction between the breather solution and the solitons. Correspondingly, the dynamic properties of the solutions are depicted graphically. The derived solutions in this study are all new and can enlarge the exact solutions of the new extended (3 + 1)-dimensional BLMPE. Besides, they can enable us to understand nonlinear dynamic behaviours better. [ABSTRACT FROM AUTHOR]

The current research aims to look into the exact solutions (ESs) of the (2 + 1)-dimensional Boiti–Leon–Manna–Pempinelli equation (BLMPE), which describes the irrotational-incompressible fluid. The Hirota bilinear equation of the problem under consideration is developed by applying the Cole–Hopf transform. Then, the ansatz function, combined with the symbolic computation, is utilised to extract the ESs. Some new types of ESs like the multi-wave complexiton solution (MWCS), multi-wave solution (MWS) and the interaction wave solution (IWS) are successfully constructed. Furthermore, ESs such as the travelling wave solution (TWS) are also explored via the modified Kudryashov method. The dynamic characteristics of the ESs are described graphically using the Mathematica software and their physical explanations are presented. Compared with the publicly available literature, the obtained ESs are all new and have not yet been reported. The ideas in this work can be used to investigate the ESs of the other PDEs that appear in physics. [ABSTRACT FROM AUTHOR]

The primary aim of this work is to investigate the nonlinear fractional Schrödinger equation, which is adopted to describe the ultra-short pulses in optical fibers. A variety of new soliton solutions and periodic solutions are constructed by implementing three efficient mathematical approaches, namely, the improved fractional F-expansion method, fractional Bernoulli (G′/G)-expansion method and fractional cosine-sine method. Moreover, the dynamic properties of these obtained solutions are discussed by plotting some 3D and 2D figures. The employed three analytical methods can be widely adopted to solve different types of fractional evolution equations. [ABSTRACT FROM AUTHOR]

This research mainly concerned with some new solutions of the (3 + 1)‐dimensional nonlinear evolution equation (NEE). First, we extract the resonant multiple soliton solutions (RMSSs) by taking advantage of the linear superposition principle (LSP) and weight algorithm (WA). Then the non‐singular complexiton and singular complexiton solutions are developed by introducing pairs of the conjugate parameters. Besides, the complex multiple‐soliton solutions are also explored with the aid of the bilinear approach. The graph descriptions of the attained solutions are paraded to show the dynamical properties. The outcomes of this work are all new and are desirous to bring some new perspective to the investigation of the complexiton solutions to the other partial differential equations (PDEs). [ABSTRACT FROM AUTHOR]

By means of He’s fractal derivative, a new fractal (2 + 1)-dimensional Zakharov–Kuznetsov–Benjamin–Bona–Mahony equation is extracted in this paper. The semi-inverse method is employed to establish the generalized fractal variational principle. The generalized fractal variational principle can show the conservation laws through the energy form in the fractal space. Moreover, some semi-domain solutions are also explored by applying the variational approach and the one-step method namely Wang’s direct mapping method-II. The dynamics of the extracted solutions on the Cantor set are unveiled graphically. The findings of this study are expected to provide some new insights into the exploration of the fractal PDEs. [ABSTRACT FROM AUTHOR]

In this work, soluble and low-molecular-weight phenolic resol was cross-linking solidified by a solvothermal method using hexamethylenetetramine as a curing agent, which was modified with hydrophobic functional groups and sulfonated by chlorosulfonic acid. Modified and sulfonated phenolic resins were used as catalysts for the dehydration of sorbitol to isosorbide, and the effects of surface hydrophobicity, acid type and acid amount on sorbitol conversion and isosorbide yield were investigated systematically. The results showed that the introduction of 3-MPTMS by coupling with phenolic hydroxyl groups of phenolic resins can significantly enhance the surface hydrophobicity of sulfonated phenolic resins and increase the surface acid amount by the oxidation of thiol groups in 3-MPTMS using H2O2 to sulfonic acid groups. As a result, the catalytic performance of sulfonated phenolic resins with surface hydrophobicity modification was improved obviously; about 100% sorbitol conversion and 75.44% isosorbide yield could be achieved under optimal reaction conditions. Compared to commercial acid resins, sulfonated phenolic resins offer the advantages of lower cost and a more convenient preparation process. [ABSTRACT FROM AUTHOR]

To meet the demand for higher energy density in lithium‐ion batteries and expand their application range, coupling lithium metal anodes with high‐voltage cathodes is an ideal solution. However, the compatibility between lithium metal batteries and electrolytes affects their applicability. In this study, proposes a locally concentrated electrolyte based on ethyl acetate (EA) as the solvent, lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) as the lithium salt, and lithium difluorooxoborate (LiDFOB) as a sacrificial agent to enhance the low‐temperature and high‐voltage endurance of Li//Lithium cobalt oxide (LCO) batteries. The Li//LCO battery can operate within the voltage range of 3 to 4.5 V, with an initial discharge specific capacity of 174.5 mAh g−1 at 20 °C. At −40 °C, after 200 cycles, the capacity retention rate is 87.7 %. It can operate under extreme conditions of −70 °C, with a discharge specific capacity of 112.6 mAh g−1. Additionally, LCO//HC batteries using this electrolyte demonstrate excellent performance. Present work provides a new perspective for the optimization of electrolytes for low‐temperature lithium‐ion batteries. [ABSTRACT FROM AUTHOR]

This research focuses on the nonlinear coupled Davey–Stewartson Fokas system, which models pulse propagation in monomode optical fibers. In order to find the novel periodic and solitary wave solutions of the nonlinear coupled Davey–Stewartson Fokas system, we have employed two effective mathematical techniques named as the Sine‐Gordon expansion method and the simple equation method. We found after researching into previous literature that these novel solutions are unique and have never been reported. Some 3D and 2D graphs are also used to discuss the dynamical behavior of these new solutions. [ABSTRACT FROM AUTHOR]

Colitis-associated colorectal cancer has been a hot topic in public health issues worldwide. Numerous studies have demonstrated the significance of myeloid-derived suppressor cells (MDSCs) in the progression of this ailment, but the specific mechanism of their role in the transformation of inflammation to cancer is unclear, and potential therapies targeting MDSC are also unclear. This paper outlines the possible involvement of MDSC to the development of colitis-associated colorectal cancer. It also explores the immune and other relevant roles played by MDSC, and collates relevant targeted therapies against MDSC. In addition, current targeted therapies for colorectal cancer are analyzed and summarized. [ABSTRACT FROM AUTHOR]

In this work, the (2 + 1) -dimensional Kadomtsev–Petviashvili model is investigated. A novel variational scheme, namely, the variational transform wave method (VTWM), is successfully established to seek the solitary wave solution of the Kadomtsev–Petviashvili model. Furthermore, the fractal solitary solution of fractal Kadomtsev–Petviashvili model is also studied based on the local fractional derivative. Numerical examples are given to fully demonstrate that the VTWM is straightforward, efficient and attractive. Finally, the physical properties of solitary wave solutions are demonstrated by some 3D graphs. [ABSTRACT FROM AUTHOR]

The accurate detection of biogenic amines (BAs) is an important means of ensuring the quality and safety of cephalopod seafood products. In this study, the pre‐column derivatization of high‐performance liquid chromatography (HPLC) was optimized using dansyl chloride (Dns‐Cl) to detect BAs in octopus, cuttlefish, and squid. The reasons for the formation of BAs were investigated by assessing their decarboxylase activity and the rates of decomposition. The findings demonstrated that using Dns‐Cl to optimize pre‐column derivatization enabled the separation of nine different BAs. The detection limits ranged from 0.07 to 0.25 mg/L, and the results exhibited a high level of linearity (R2 ≥ 0.997). The decarboxylase activity and biodegradation rate positively correlated with the formation of BAs at temperatures below 0°C. Notably, the decarboxylase activity of octopus, cuttlefish, and squid exhibited a significant increase with prolonged storage time, and formyltransferase and carbamate kinase may be the key decarboxylase in cephalopod products. These findings serve as a valuable reference for further investigations into the mechanisms behind BAs production and the development of control technologies for BAs in cephalopod products. This study has successfully demonstrated the effectiveness of the Dns‐Cl pre‐column derivatization‐HPLC method in accurately and efficiently detecting BAs in octopus, cuttlefish, and squid. Moreover, it highlights the influence of decarboxylase content and biodegradation rate on the formation of BAs. Importantly, this method can serve as a reference for detecting BAs in various seafood products. [ABSTRACT FROM AUTHOR]

The intelligent monitoring of cutting tools used in the manufacturing industry is steadily becoming more convenient. To accurately predict the state of tools and tool breakages, this study proposes a tool wear prediction technique based on multi-sensor information fusion. First, the vibrational, current, and cutting force signals transmitted during the machining process were collected, and the features were extracted. Next, the Kalman filtering algorithm was used for feature fusion, and a predictive model for tool wear was constructed by combining the ResNet and long short-term memory (LSTM) models (called ResNet-LSTM). Experimental data for thin-walled parts obtained under various machining conditions were utilized to monitor the changes in tool conditions. A comparison between the ResNet and LSTM tool wear prediction models indicated that the proposed ResNet-LSTM model significantly improved the prediction accuracy compared to the individual LSTM and ResNet models. Moreover, ResNet-LSTM exhibited adaptive noise reduction capabilities at the front end of the network for signal feature extraction, thereby enhancing the signal feature extraction capability. The ResNet-LSTM model yielded an average prediction error of 0.0085 mm and a tool wear prediction accuracy of 98.25%. These results validate the feasibility of the tool wear prediction method proposed in this study. [ABSTRACT FROM AUTHOR]

The lack of suitable channel semiconductor materials has been a limiting factor in the development of tunneling field-effect transistor (TFET) architectures due to the stringent criteria of both air stability and excellent gate-tunable electronic properties. Here, we report the performance limits of sub-10-nm double-gated monolayer (ML) BiN TFETs by utilizing first-principles quantum-transport simulations. We find that ML BiN possesses an indirect bandgap of 0.8 eV and effective masses of 0.24m0 and 2.24m0 for electrons and holes, respectively. The n-type BiN TFETs exhibit better performance than the p-type ones, and the on-state current can well satisfy the requirements of the International Roadmap for Devices and Systems for both high-performance and low-power standards. Notably, we find that the BiN TFETs exhibit distinguished gate controllability with an ultra-low subthreshold swing below 60 mV/decade even with a small gate length of 6 nm, which is superior to the existing field-effect transistors, such as black phosphorus TFETs, GeSe TFETs, and BiN metal–oxide–semiconductor field-effect transistors. Furthermore, the BiN TFETs are endowed with the potential to realize high switching speed and low-power consumption applications because of their extremely short delay time and ultra-low power-delay product. Our results reveal that the ML BiN is a highly competitive channel material for the next-generation TFETs. [ABSTRACT FROM AUTHOR]

In this work, a new fractal pseudo-parabolic equation is derived by means of He's fractal derivative. The semi-inverse method (SIM) is employed to develop the generalized fractal variational principle (GFVP), which can reveal the energy conservation law in the fractal space and provide some new insights on the study of the variational method. [ABSTRACT FROM AUTHOR]

In this paper, the fractional Schrödinger equation is described with beta derivative, which is used to elucidate the dynamic interaction of ultra-short pulses with quantum properties in optical fibers. This work is to study the solitary wave and periodic solutions of the fractional Schrödinger equation by employing three powerful and simple mathematical approaches like fractional Kudryashov method, fractional cosine–sine method and fractional tanh function method. The acquired outcomes illustrate that the proposed three computational approaches are simple, efficient, concise and can be adopted to study more complex phenomena. Finally, the dynamical behavior of these acquired solitary wave solutions is illustrated by sketching some 3D figures with proper parameters. [ABSTRACT FROM AUTHOR]

The primary objective of this study is to examine the behavior of the nonlinear Kaup-Newell equation. By employing the modified Kudryashov method and extended tanh function method, we have successfully derived novel solitary wave and periodic solutions. These new solutions are presented in trigonometric, hyperbolic and exponential function types. The proposed two approaches are efficient, direct and fascinating. These newly discovered solutions are illustrated using two-dimensional and three-dimensional graphs, incorporating suitable parameters values. These graphs are crucial for elucidating the dynamic properties of optical fibers. [ABSTRACT FROM AUTHOR]

Objectives: There is a strong association among risk factors for oral cancer (ORCA), such as smoking, alcohol consumption, fiber intake, and red meat intake. The apparent synergistic effects reported in previous observational studies may also underestimate the independent effects. Our study aims to further explore the potential etiology and causality of oral cancer. Materials and methods: This study used the genome-wide associations study database (GWAS) in European populations for Mendelian randomization (MR) analysis to explore exposure factors associated with ORCA and detect the genetic causality between these exposures and ORCA risk. Results: Our results demonstrated that in univariate MR analysis, the five exposure factors (celery intake, average weekly beer and cider intake, spirits intake, and pork intake) were risk factors, and oily fish intake was a safety factor, but in multivariate MR analysis, pork intake had the greatest impact on oral cancer when the five food/drink intakes were simultaneously consumed. Conclusions: The causal relationship between the five exposure factors (oily fish intake, celery intake, pork intake, average weekly beer and cider intake, and spirits intake) and oral cancer was analyzed. The causal effects of pork on oral cancer may be underestimated. Clinical relevance: Prevention of oral cancer requires better education about lifestyle-related risk factors, and improved awareness and tools for early diagnosis. Our study provides some risk factors that cannot be ignored for the cause prevention of oral cancer, such as pork intake, and its role in oral cancer prevention and control. [ABSTRACT FROM AUTHOR]

Background: Iatrogenic complications of endovascular treatment for central venous stenosis have not yet been reported. Here we present a case of a patient on maintenance hemodialysis who developed catheter-related superior vena cava syndrome and subsequently suffered from hemorrhagic pericardial tamponade after undergoing percutaneous transluminal angioplasty and stenting. Case presentation: A 72-year-old male patient presented with uremia, and had been receiving maintenance hemodialysis for the past five years. The patient initially presented with dysfunction of the dialysis catheter (a cuffed tunneled double-lumen catheter in the right internal jugular vein). Imaging examination revealed a segmental occlusion of the superior vena cava stretching from the distal end of the dialysis catheter up to right atrium entrance, apparent compensatory dilatation of the azygos vein, and abundant subcutaneous collaterals. The patient underwent percutaneous transluminal balloon dilatation and stenting (covered stent) of the superior vena cava in the Cath Lab. During the procedure, with forceful advancement of the guidewire, it was observed to progress for a distance before a "smoke" appeared, and an outward spillage of contrast agent was visible, which suggested a possible vessel puncture leading into the mediastinum. Unfortunately, postoperative hemorrhagic pericardial tamponade occurred and the patient developed cardiogenic shock. He experienced symptoms included chest tightness and breath shortness with a recorded blood pressure of 84/60mmHg. After draining 600 ml of bloody fluid through pericardiocentesis, the patient's symptoms alleviated and his condition improved. Conclusions: The case emphasizes the need for increased attention to iatrogenic endovascular injuries during catheter placement and endovascular treatment, such as causing pericardial hemorrhage leading to cardiac tamponade. [ABSTRACT FROM AUTHOR]

We report collinear strong-field terahertz (THz) generation from the organic crystal 4-N, N-dimethlamino-4-N-methyl-stilbazolium 2,4,6-trimethyl benzenesulfonate (DSTMS), driven by an industrial-grade ytterbium (Yb) laser operating at 1030 nm. The laser pulse duration is compressed from 800 to 90 fs by using a multi-pass-cell compressor. The output THz energy reaches 0.4 μ J, with a conversion efficiency of 0.22%. The spectrum covers over 0.1–6 THz with a peak electric field of 236 kV/cm. The phase matching condition and material absorption are illustrated. We demonstrate that a 1030 nm Yb-laser is used to pump organic crystal DSTMS for efficient THz generation in a simple collinear geometry, which provides a promising THz source based on an industrial-grade ultrafast laser. [ABSTRACT FROM AUTHOR]

The central purpose of this paper is to explore the nonlinear dynamics of the (2+1)-dimensional Kadomtsev–Petviashvili equation (KPE). The multiple soliton solutions (MSSs) are constructed via applying the Hirota method. Then the soliton molecules on the (x,y)-, (x,t)- and (y,t)-planes are extracted via imposing the velocity resonance conditions to the MSSs. Eventually, two effective techniques, the sub-equation approach (SEA) and the variational approach (VA), are employed to probe some other diverse wave solutions, which are the bright wave, dark wave, singular wave and the singular periodic wave solutions. The dynamics of the extracted solutions are unveiled graphically to exhibit the physical attributes. The attained solutions in this paper can enlarge the exact solutions of the (2+1)-dimensional KPE and enable us to understand the nonlinear dynamic behaviors better. [ABSTRACT FROM AUTHOR]

This work aims to explore the optical solitons of the Kaup–Newell model (KNM) which describes the glamorous technology of sub-picosecond pulses that spread via single-mode optical fibres using two innovative methods, namely Wang’s Bäcklund transformation-based method (WBTBM) and Wang’s direct mapping method (WDMM). Different kinds of exact solutions expressed in the form of the rational function, Exp function, sin–cos function, sinh–cosh function, hyperbolic function (sech function and csch function) and trigonometric function (sec function and csc function) are obtained, which include the bright soliton, dark soliton, singular soliton and other travelling wave solutions. To reveal the dynamic behaviours of the different solutions, the 3D plots, 2D contours and 2D curves are drawn with the help of the Mathematica software. The findings in this work confirm that the mentioned methods are effective, straightforward and powerful, and can be used to handle other partial differential equations (PDEs) arising in the optics. [ABSTRACT FROM AUTHOR]

AbstractTyrosol is a principle phenolic compound present in olive oil and wine with great pharmacological potentials due to its strong antioxidant property. Its application can be highly extended by increasing its lipophilicity through esterification. In this study, tyrosol esters were synthesized by enzymatic transesterification of tyrosol with vinyl esters, with a commercial lipase from Novozymes (Novozym 435, Candida antarctica lipase B (CALB) immobilized on macroporous acrylic resin beads) as the catalyst, both in organic solvents and in ionic liquids. Methyl tert-butyl ether (MTBE) was the best solvent, offering complete conversions towards the synthesis of tyrosol esters with varying chain lengths (C2-C18) within 1 h. Taking the enzymatic transesterification between tyrosol and vinyl acetate as the model reaction, 18 organic solvents and 24 ionic liquids were screened, and their solvent properties (i.e. hydrophobicity, polarity, viscosity, water activity, and partition coefficients of substrate and product) were correlated to the enzyme activity. Upon enzyme screening, four new lipases were found to be highly efficient, relative to the best-performed Novozym 435 and Lipozyme TLIM (Thermomyces lanuginosus lipase (TLL) immobilized on silica gel), in tyrosol ester synthesis. This work provides enzymatic methods of esterifying tyrosol that are much more efficient than those reported in literature, and will shed light on re-consideration of the roles of solvents in nonaqueous enzymology. [ABSTRACT FROM AUTHOR]

The fractional derivatives have been widely applied in many fields and has attracted widespread attention. This paper extracts a new fractional (3+1)-dimensional modified Zakharov–Kuznetsov equation (MZKe) with the local fractional derivative (LFD) for the first time. Two special functions, namely, the LT δ (Ξ δ) and LC δ (Ξ δ) functions that are derived on the basis of the Mittag-Leffler function (MLF) defined on the Cantor set (CS), are employed to construct the auxiliary trial function to look into the exact solutions (ESs). Aided by Yang's non-differentiable (ND) transformation, six groups of the ND ESs are found. The ND ESs on the CS for δ = ln 2 / ln 3 are depicted graphically. Additionally, as a comparison, the ESs of the classic (3+1)-dimensional MZKe for δ = 1 are also illustrated. The outcomes reveal that the derived method is powerful and effective, and can be used to deal with the other local fractional PDEs. [ABSTRACT FROM AUTHOR]

The aim of this study is to explore some semi-domain soliton solutions for the fractal (3+1)-dimensional generalized Kadomtsev–Petviashvili–Boussinesq equation (GKPBe) within He's fractal derivative. First, the fractal soliton molecules are plumbed by combining the Hirota equation and fractal two-scale transform. Second, the Bernoulli sub-equation function approach together with the fractal two-scale transform is employed to investigate the other soliton solutions, which include the kink soliton and the rough wave soliton solutions. The impact of the different fractal orders on the physical behaviors of the semi-domain soliton solutions is also discussed graphically. The methods mentioned in this research are expected to provide some new viewpoints on the behaviors of the fractal PDEs. [ABSTRACT FROM AUTHOR]

In ocean engineering, the long- and short-wave interaction system represents a crucial nonlinear evolution equation that elucidates the resonant interaction phenomenon between ocean waves. In this study, we describe the fractional long and short-wave interaction (FLSWI) system employing the M-truncated derivative. Subsequently, we employ the extended fractional tanh χ − coth χ and the fractional csc h χ methods to address the FLSWI system. These two approaches yields novel and intriguing soliton solutions. To further elucidate the derived soliton solutions, three-dimensional visualizations are constructed and analyzed. [ABSTRACT FROM AUTHOR]

In this paper, we focus on the investigations on the stochastic stability and the stochastic resonance (SR) phenomena for a FitzHugh-Nagumo system with time delay induced by a multiplicative non-Gaussian colored noise and an additive Gaussian colored noise. By use of the fast descent method, the unified colored noise approximation and the two-state theory for the SR, the stationary probability density function (SPDF) and the signal-to-noise ratio (SNR) caused by different noise terms and time delay are explored. The investigation results indicate that the two noise intensities, time delay and the departure parameter from the Gaussian noise can all reduce the probability density around the two stable states and destroy the stability of the neural system; while the two noise correlation times τ and τ 0 can both improve the probability density around both stable states and reinforce the biological stability of the neural system. As regards the SNR, it is found that the two noise intensities and the departure coefficient can all weaken the SR effect, while time delay α and the correlation time τ of the multiplicative noise will always magnify the SR phenomenon. It is worth to mention that the correlation time τ 0 of the additive noise can stimulate the SR effect, but not alter the maximum of the SNR. [ABSTRACT FROM AUTHOR]

Follow-up experimental designs are frequently employed in a wide range of scientific studies and industries. Lower bounds of average mixture discrepancy for row augmented designs are determined in this paper utilizing the level permutation technique, which is also used to analyse the uniformity of row augmented designs with asymmetrical factorials. Between the row augmented designs and its initial designs or follow-up designs, quantitative relationships of lower bounds of average mixture discrepancy are constructed. Additionally, a proposal is made for the construction algorithm of asymmetrical uniform row augmented designs. Numerical examples indicate that the asymmetrical uniform row augmented designs can be constructed with high efficiency and recommended for use in practice. [ABSTRACT FROM AUTHOR]

In this research, we focus on some novel exact solutions of the new (2 + 1)-dimensional shallow water wave equation (SWWE). First, the soliton molecules on the (x,y)-, (x,t)- and (y,t)-planes are constructed via assigning the velocity resonance conditions to the multiple soliton solutions (MSSs) that can be derived via the Hirota method. Second, the periodic wave solutions are explored by means of the new homoclinic approach. Finally, the other diverse wave solutions including the kink wave, singular wave and the singular periodic wave solutions are also plumbed by the sub-equation approach (SEA). The dynamic performances of the extracted solutions are presented graphically to unveil the nonlinear physical characteristics. As we know, the extracted solutions in this paper are all new and have not been investigated in other literature, which can help us make sense of the nonlinear dynamics of the new (2 + 1)-dimensional SWWE better. [ABSTRACT FROM AUTHOR]

Metabolic reprogramming, which is recognized as a hallmark of cancer, refers to the phenomenon by which cancer cells change their metabolism to support their increased biosynthetic demands. Tumor cells undergo substantial alterations in metabolic pathways, such as glycolysis, oxidative phosphorylation, pentose phosphate pathway, tricarboxylic acid cycle, fatty acid metabolism, and amino acid metabolism. Latest studies have revealed that long non-coding RNAs (lncRNAs), a group of non-coding RNAs over 200 nucleotides long, mediate metabolic reprogramming in tumor cells by regulating the transcription, translation and post-translational modification of metabolic-related signaling pathways and metabolism-related enzymes through transcriptional, translational, and post-translational modifications of genes. In addition, lncRNAs are closely related to the tumor microenvironment, and they directly or indirectly affect the proliferation and migration of tumor cells, drug resistance and other processes. Here, we review the mechanisms of lncRNA-mediated regulation of glucose, lipid, amino acid metabolism and tumor immunity in gastrointestinal tumors, aiming to provide more information on effective therapeutic targets and drug molecules for gastrointestinal tumors. [ABSTRACT FROM AUTHOR]

Introduction: This study was to investigate the diagnostic value of percutaneous closed pleural brushing (CPBR) followed by cell block technique for malignant pleural effusion (MPE) and the predictive efficacy of pleural fluid carcinoembryonic antigen (CEA) for epidermal growth factor receptor (EGFR) mutations in lung adenocarcinoma patients with MPE. Methods: All patients underwent closed pleural biopsy (CPB) and CPBR followed by cell block examination. MPE‐positive diagnostic rates between the two methods were compared. Univariate and multivariate analyses were performed to determine factors influencing the EGFR mutations. Receiver operating characteristic (ROC) curve was used to analyze the predictive efficacy of pleural fluid CEA for EGFR mutations. Results: The cumulative positive diagnostic rates for MPE after single and twice CPBR followed by cell block examination were 80.5% and 89.0%, higher than CPB (45.7%, 54.3%) (P < 0.001). Univariate analysis showed that EGFR mutation was associated with pleural fluid and serum CEA (P < 0.05). Multivariate analysis showed that pleural fluid CEA was an independent risk factor for predicting EGFR mutation (P < 0.001). The area under the curve (AUC) of pleural fluid CEA for EGFR mutation prediction was 0.774, higher than serum CEA (P = 0.043), but no difference with the combined test (P > 0.05). Conclusion: Compared with CPB, CPBR followed by the cell block technique can significantly increase the positive diagnostic rate of suspected MPE. CEA testing of pleural fluid after CPBR has a high predictive efficacy for EGFR mutation in lung adenocarcinoma patients with MPE, implying pleural fluid extracted for cell block after CPBR may be an ideal specimen for genetic testing. [ABSTRACT FROM AUTHOR]

The polymer translocation through a nanopore from a donor space (or named cis side) to a receiver space (trans side) in the chaperone-induced crowded environment has attracted increasing attention in recent years due to its significance in biological systems and technological applications. In this work, we mainly focus on the effects of chaperone concentration and chaperone-polymer interaction on the polymer translocation. By assuming the polymer translocation to be a quasi-equilibrium process, the free energy F of the polymer can be estimated by Rosenbluth-Rosenbluth method and then the translocation time τ can be calculated by Fokker-Plank equation based on the obtained free energy landscape. Our calculation results show that the translocation time can be controlled by independently tuning the chaperone concentration and chaperone-polymer interaction at the cis side or the trans side. There exists a critical chaperone-polymer attraction ε*=−0.2 at which the volume exclusion and interaction effects of the chaperone can balance each other. Additionally, we also find that at large chaperone-polymer attraction, the translocation time is mainly governed by the diffusion coefficient of the polymer. [ABSTRACT FROM AUTHOR]

• Vibro-acoustic modulation analysis is carried out to identify the micro-cracks in steel strands. • Modulated signal bispectrum is proposed to analyze the nonlinear signal of contact-type defect. • The modulated signal bispectrum provides clear peak detection under high noise conditions. • Numerical and experimental tests of straight/helical wire and multi-wire strands are verified. Under continuous environmental erosion and long-time high tension, fatigue micro-cracks of bridge cables appear frequently to challenge the reliability of cables. The vibro-acoustic modulation analysis is adopted because of its sensitivity to contact-type defects, especially fatigue cracks. In this paper, using multiple sets of low-frequency vibration and high-frequency ultrasonic excitation, the propagation of the ultrasonic wave in the steel strands is studied. Then, the modulated signal bispectrum is proposed to improve the detection reliability of nonlinear modulation components in the nonlinear vibro-acoustic modulation signal of the contact-type defect. The numerical simulations and laboratory tests of straight wire, helical wire, and multi-wire strands are carried out for micro-crack detection to verify the robustness of the proposed method. Compared with the traditional method, the modulated signal bispectrum can still produce clearer peak detection under high noise conditions. The results show that it provides a promising, dynamic and rapid cable defect detection technique. [ABSTRACT FROM AUTHOR]

Introduction: There are sex differences in the extent, severity, and outcomes of coronary artery disease. We aimed to assess the influence of sex on coronary atherosclerotic plaque activity measured using coronary 18F-sodium fluoride (18F-NaF) positron emission tomography (PET), and to determine whether 18F-NaF PET has prognostic value in both women and men.In a post-hoc analysis of observational cohort studies of patients with coronary atherosclerosis who had undergone 18F-NaF PET CT angiography, we compared the coronary microcalcification activity (CMA) in women and men.Baseline 18F-NaF PET CT angiography was available in 999 participants (151 (15%) women) with 4282 patient-years of follow-up. Compared to men, women had lower coronary calcium scores (116 [interquartile range, 27–434] versus 205 [51–571] Agatston units; p = 0.002) and CMA values (0.0 [0.0-1.12] versus 0.53 [0.0-2.54], p = 0.01). Following matching for plaque burden by coronary calcium scores and clinical comorbidities, there was no sex-related difference in CMA values (0.0 [0.0-1.12] versus 0.0 [0.0-1.23], p = 0.21) and similar proportions of women and men had no 18F-NaF uptake (53.0% (n = 80) and 48.3% (n = 73); p = 0.42), or CMA values > 1.56 (21.8% (n = 33) and 21.8% (n = 33); p = 1.00). Over a median follow-up of 4.5 [4.0–6.0] years, myocardial infarction occurred in 6.6% of women (n = 10) and 7.8% of men (n = 66). Coronary microcalcification activity greater than 0 was associated with a similarly increased risk of myocardial infarction in both women (HR: 3.83; 95% CI:1.10-18.49; p = 0.04) and men (HR: 5.29; 95% CI:2.28–12.28; p < 0.001).Although men present with more coronary atherosclerotic plaque than women, increased plaque activity is a strong predictor of future myocardial infarction regardless of sex.Methods: There are sex differences in the extent, severity, and outcomes of coronary artery disease. We aimed to assess the influence of sex on coronary atherosclerotic plaque activity measured using coronary 18F-sodium fluoride (18F-NaF) positron emission tomography (PET), and to determine whether 18F-NaF PET has prognostic value in both women and men.In a post-hoc analysis of observational cohort studies of patients with coronary atherosclerosis who had undergone 18F-NaF PET CT angiography, we compared the coronary microcalcification activity (CMA) in women and men.Baseline 18F-NaF PET CT angiography was available in 999 participants (151 (15%) women) with 4282 patient-years of follow-up. Compared to men, women had lower coronary calcium scores (116 [interquartile range, 27–434] versus 205 [51–571] Agatston units; p = 0.002) and CMA values (0.0 [0.0-1.12] versus 0.53 [0.0-2.54], p = 0.01). Following matching for plaque burden by coronary calcium scores and clinical comorbidities, there was no sex-related difference in CMA values (0.0 [0.0-1.12] versus 0.0 [0.0-1.23], p = 0.21) and similar proportions of women and men had no 18F-NaF uptake (53.0% (n = 80) and 48.3% (n = 73); p = 0.42), or CMA values > 1.56 (21.8% (n = 33) and 21.8% (n = 33); p = 1.00). Over a median follow-up of 4.5 [4.0–6.0] years, myocardial infarction occurred in 6.6% of women (n = 10) and 7.8% of men (n = 66). Coronary microcalcification activity greater than 0 was associated with a similarly increased risk of myocardial infarction in both women (HR: 3.83; 95% CI:1.10-18.49; p = 0.04) and men (HR: 5.29; 95% CI:2.28–12.28; p < 0.001).Although men present with more coronary atherosclerotic plaque than women, increased plaque activity is a strong predictor of future myocardial infarction regardless of sex.Results: There are sex differences in the extent, severity, and outcomes of coronary artery disease. We aimed to assess the influence of sex on coronary atherosclerotic plaque activity measured using coronary 18F-sodium fluoride (18F-NaF) positron emission tomography (PET), and to determine whether 18F-NaF PET has prognostic value in both women and men.In a post-hoc analysis of observational cohort studies of patients with coronary atherosclerosis who had undergone 18F-NaF PET CT angiography, we compared the coronary microcalcification activity (CMA) in women and men.Baseline 18F-NaF PET CT angiography was available in 999 participants (151 (15%) women) with 4282 patient-years of follow-up. Compared to men, women had lower coronary calcium scores (116 [interquartile range, 27–434] versus 205 [51–571] Agatston units; p = 0.002) and CMA values (0.0 [0.0-1.12] versus 0.53 [0.0-2.54], p = 0.01). Following matching for plaque burden by coronary calcium scores and clinical comorbidities, there was no sex-related difference in CMA values (0.0 [0.0-1.12] versus 0.0 [0.0-1.23], p = 0.21) and similar proportions of women and men had no 18F-NaF uptake (53.0% (n = 80) and 48.3% (n = 73); p = 0.42), or CMA values > 1.56 (21.8% (n = 33) and 21.8% (n = 33); p = 1.00). Over a median follow-up of 4.5 [4.0–6.0] years, myocardial infarction occurred in 6.6% of women (n = 10) and 7.8% of men (n = 66). Coronary microcalcification activity greater than 0 was associated with a similarly increased risk of myocardial infarction in both women (HR: 3.83; 95% CI:1.10-18.49; p = 0.04) and men (HR: 5.29; 95% CI:2.28–12.28; p < 0.001).Although men present with more coronary atherosclerotic plaque than women, increased plaque activity is a strong predictor of future myocardial infarction regardless of sex.Conclusion: There are sex differences in the extent, severity, and outcomes of coronary artery disease. We aimed to assess the influence of sex on coronary atherosclerotic plaque activity measured using coronary 18F-sodium fluoride (18F-NaF) positron emission tomography (PET), and to determine whether 18F-NaF PET has prognostic value in both women and men.In a post-hoc analysis of observational cohort studies of patients with coronary atherosclerosis who had undergone 18F-NaF PET CT angiography, we compared the coronary microcalcification activity (CMA) in women and men.Baseline 18F-NaF PET CT angiography was available in 999 participants (151 (15%) women) with 4282 patient-years of follow-up. Compared to men, women had lower coronary calcium scores (116 [interquartile range, 27–434] versus 205 [51–571] Agatston units; p = 0.002) and CMA values (0.0 [0.0-1.12] versus 0.53 [0.0-2.54], p = 0.01). Following matching for plaque burden by coronary calcium scores and clinical comorbidities, there was no sex-related difference in CMA values (0.0 [0.0-1.12] versus 0.0 [0.0-1.23], p = 0.21) and similar proportions of women and men had no 18F-NaF uptake (53.0% (n = 80) and 48.3% (n = 73); p = 0.42), or CMA values > 1.56 (21.8% (n = 33) and 21.8% (n = 33); p = 1.00). Over a median follow-up of 4.5 [4.0–6.0] years, myocardial infarction occurred in 6.6% of women (n = 10) and 7.8% of men (n = 66). Coronary microcalcification activity greater than 0 was associated with a similarly increased risk of myocardial infarction in both women (HR: 3.83; 95% CI:1.10-18.49; p = 0.04) and men (HR: 5.29; 95% CI:2.28–12.28; p < 0.001).Although men present with more coronary atherosclerotic plaque than women, increased plaque activity is a strong predictor of future myocardial infarction regardless of sex. [ABSTRACT FROM AUTHOR]

The signal transducer and activator of transcription 3 (STAT3), a member of the STAT family, resides in the nucleus to regulate genes essential for vital cellular functions, including survival, proliferation, self-renewal, angiogenesis, and immune response. However, continuous STAT3 activation in tumor cells promotes their initiation, progression, and metastasis, rendering STAT3 pathway inhibitors a promising avenue for cancer therapy. Nonetheless, these inhibitors frequently encounter challenges such as cytotoxicity and suboptimal biocompatibility in clinical trials. A viable strategy to mitigate these issues involves delivering STAT3 inhibitors via drug delivery systems (DDSs). This review delineates the regulatory mechanisms of the STAT3 signaling pathway and its association with cancer. It offers a comprehensive overview of the current application of DDSs for anti-STAT3 inhibitors and investigates the role of DDSs in cancer treatment. The conclusion posits that DDSs for anti-STAT3 inhibitors exhibit enhanced efficacy and reduced adverse effects in tumor therapy compared to anti-STAT3 inhibitors alone. This paper aims to provide an outline of the ongoing research and future prospects of DDSs for STAT3 inhibitors. Additionally, it presents our insights on the merits and future outlook of DDSs in cancer treatment. The integration of drug delivery systems with inhibitors that target STAT3 effectively impedes the STAT3 signaling pathway in cancer. Achieved through modalities such as chemotherapy, immunotherapy, and targeted therapy, this integration consequently amplifies the therapeutic efficacy. [Display omitted] [ABSTRACT FROM AUTHOR]

The acceleration performance of turbofan engine is mainly limited by the surge boundary of high-pressure compressor (HPC). A certain amount of surge margin (SM) is reserved between the boundary and the acceleration schedule (AS) of acceleration control to avoid the risk caused by intake distortion, etc. However, the performance improvement by low SM design is the requirement for advanced engines. Hence it must execute a fault-tolerant strategy for the impact of sensor error, fuel metering error, etc. This paper proposes a method by adopting four ASs for weighted average to replace the single AS. The weights are altered by the multi-layer perceptron with reference to the real-time fuel results from four ASs, intake condition and rotor speed. For safety and accuracy, an exponential Gumbel loss function is introduced into the model training. The simulation results demonstrate that the method can significantly tolerate the impact of a single fault and the normal deviations of other factors without causing SM of HPC to be less than 3.6%. These also indicate that the acceleration time on the ground does not exceed acceptable 5 s, with a median that is 0.34 s less than the minimum method of two ASs within the flight envelope. • The method can tolerate a single fault without the surge and sharp performance drop. • The four dissimilar acceleration schedules are used for the total estimation accuracy. • An asymmetric loss function is introduced to balance the safety and performance. [ABSTRACT FROM AUTHOR]

• A novel combined prediction system for SWH prediction is proposed. • Developed an integrated feature extraction method. • Multi-criteria decision-making method is introduced to select sub-models. • A multi-objective homogeneous nuclear molecular optimization is proposed. • A hybrid kernel density estimation method is developed. Accurate prediction of significant wave height is paramount for the effective design, operation, and maintenance of wave energy converters. However, current research falls short in achieving precise and stable point predictions, along with comprehensive uncertainty analysis of significant wave height. To address this gap, this study presents a comprehensive significant wave height combined prediction system. This integrated system encompasses outlier detection utilizing Autoencoders, sophisticated feature engineering, a multi-criteria decision-based model selection methodology, a multi-objective homogeneous nuclear molecular optimization algorithm, and a hybrid kernel density estimation technique. To tackle the critical issue of model selection within ensemble prediction, we introduce a multi-criteria compromise solution ranking algorithm known as VIKOR for the selection of sub-models. Additionally, a novel multi-objective homogeneous nuclear molecular optimization algorithm is proposed, which incorporates joint opposing selection and an elite retention strategy to effectively manage multiple objectives simultaneously, yielding Pareto optimal solutions for combining weights. Furthermore, a hybrid kernel density estimation approach is developed, surpassing previous methods reliant on a single kernel function and fixed bandwidth, thereby achieving a more precise fit to the distribution of wave height data. The effectiveness of the proposed model is rigorously evaluated using wave height datasets from three distinct locations. The experimental results convincingly demonstrate that the significant wave height combined prediction system outperforms existing solutions, excelling in both point and interval predictions of significant wave height. [ABSTRACT FROM AUTHOR]

• Laquinimod can ameliorate mitochondrial dysfunction induced by oxidative stress in nucleus pulposus cell. • Laquinimod can mitigate the degeneration of intervertebral discs induced by acupuncture in rat. • Laquinimod can effectively regulate the metabolic homeostasis of the intervertebral disc by mitigating the inflammatory response induced by oxidative stress. Low back pain (LBP) caused by intervertebral disc degeneration (IVDD) is a significant global health concern. It is necessary to investigate the underlying pathological mechanisms leading to IVDD and develop precise treatment strategies for this condition. Considering the well-established anti-inflammatory properties and ability to reduce oxidative stress in various diseases, for the first time we aim to explore the potential of Laquinimod in alleviating IVDD. We used hydrogen peroxide (H 2 O 2) to simulate the oxidative stress microenvironment in IVDD, and Laquinimod for intervention purposes. Western blot analysis, quantitative real-time polymerase chain reaction (qRT-PCR), enzyme-linked immunosorbent assay (ELISA), and immunofluorescence assay were used to measure the expression levels of inflammatory cytokines, catabolic enzymes, and markers of extracellular matrix (ECM) synthesis in nucleus pulposus (NP) cells. In addition, dichlorofluorescin-diacetate (DCFH-DA) and JC-1 fluorescent probes, flow cytometry analysis, and qRT-PCR were used to measure mitochondrial function and apoptosis in NP cells under conditions of oxidative stress. An acupuncture-induced rat model of IVDD was established to further evaluate the efficacy of Laquinimod in alleviating IVDD in vivo. Our findings showed that Laquinimod significantly reduced the oxidative stress-induced inflammatory response in NP cells, downregulated the expression of catabolic enzymes, and markedly enhanced ECM degradation by inhibiting the NF-κB signaling pathway. The administration of Laquinimod concurrently improved the mitochondrial functional state and reduced apoptosis in NP cells. Additionally, in vivo experiments in rats showed that Laquinimod significantly alleviated acupuncture-induced IVDD. Collectively, the findings of this study provide new insights into the therapeutic potential of Laquinimod as a treatment for oxidative stress-induced IVDD. [ABSTRACT FROM AUTHOR]

This paper proposes an impact detection method based on the ratio of mechanoluminescence (ML) intensity, as an improvement over traditional methods that rely on absolute ML intensity. The study utilized two types of ML materials, ZnS:Cu2+ and ZnS:Mn2+, which were physically mixed and embedded them in polydimethylsiloxane (PDMS) to fabricate a flexible film sensor. A drop ball experimental setup was constructed, and the ML spectrum of the film sensor under the impact of a small ball was collected through a spectrometer. This established the relationship between impact velocity and the ratio of ML intensities. Experiments proved that the distance of spectral collection has a minimal effect on the measurement results of this method. Compared to traditional methods based on absolute ML intensity, this method has stronger resistance to environmental interference and better applicability. This new impact detection method based on the ratio of ML intensities has broad application prospects in future engineering applications, safety assessments, and material testing. [Display omitted] • Utilizing two different mechanoluminescent materials mixed together to create a flexible film sensor. • A quantitative relationship is established between impact velocity and the ratio of emitted light intensities. • This impact detection method demonstrates good resistance to environmental interference. [ABSTRACT FROM AUTHOR]

• PtO 2 ˉ anion has two energetically degenerate isomers. • The D ∞h symmetric linear structure competed with C 2v symmetric bent structure. • PtO 2 ˉ anion indicate that its σ and π double bonding patterns. • PtO 2 neutral exhibits σ and π antiaromaticity. This study investigates the structures and bonding properties of gas-phase PtO 2 ˉ anion and PtO 2 neutral using anion photoelectron spectroscopy and theoretical calculations. Notably, both species adopt a D ∞h symmetric linear O−Pt−O structure, with PtO 2 neutral featuring notably shorter Pt–O bond lengths. Charge transfer from the central Pt atom to the terminal O 2 motifs is evident in both clusters, as indicated by Natural Population Analysis (NPA). Chemical bonding analysis reveals σ and π double bonding patterns in PtO 2 ˉ anion, while PtO 2 neutral demonstrates σ and π antiaromaticity. This research enhances our understanding of platinum oxide clusters and their potential in developing co-catalysts for efficient solar-driven water splitting. [ABSTRACT FROM AUTHOR]

This paper focuses on addressing a critical challenge in 3D printing: managing energy consumption. 3D printing has emerged as a transformative technology in manufacturing, but its energy demands are a key concern for cost-effectiveness and sustainability. To tackle this challenge, an energy management system is proposed to leverage manifold model morphing and semi-supervised machine learning, to reduce production costs for 3D printing. The manifold model is a mathematical representation of the 3D object to be printed, and the refinement process involves optimizing the morphing parameters of the manifold model to achieve desired printing outcomes. To enable flexibility in the grasping space, the semi-supervised machine learning is then incorporated to leverage unlabeled data, enhancing the accuracy and robustness of the energy management system. The proposed system addresses the challenges of limited labeled data and complex morphologies of biological products in layered additive manufacturing. The energy management system is more applicable to soft robotics and biomedical products. The performance of the proposed system is evaluated through extensive experiments that demonstrate its effectiveness and efficacy in predicting and managing energy consumption in 3D printing. Our system offers a practical solution for estimating energy consumption in the design stage, and thus guides the designers to adopt the optimal part geometry and process planning for cleaner production. The results highlight that the proposed system is capable of optimizing energy usage in 3D printing, contributing to the advancement of green and sustainable industrial practices. • A manifold morphing method is proposed to generate multiple family-products. • A kinematics model of the self-grasping manifold is constructed for validation. • A semi-supervised deep network is designed to leverage generated family-products. • The system addresses the challenges of limited sample data in energy management. [ABSTRACT FROM AUTHOR]

• The recovery and recrystallization behavior of an yttria dispersion reinforced tungsten plate with 67 % rolled thickness reduction was investigated in detail. • The stored energy of rolled microstructure is texture dependent. • The recrystallized texture inherits the deformed texture and is mainly composed of γ fiber texture. • Yttria particles can inhibit the migration of the front of recrystallized grain and lead to the form of concave grain. The thermal stability of an yttria particle dispersion strengthening tungsten (W-2vol%Y 2 O 3) plate with 67 % rolling thickness reduction (WY67) fabricated by powder metallurgy and warm rolling is investigated through isochronous annealing and isothermal annealing. Hardness testing of annealed specimens allows tracking the degradation of the mechanical properties and electron backscatter diffraction (EBSD) was used to characterize the corresponding microstructure. Isochronous annealing for 1 hour between 1150 °C and 1450 °C indicates that the recrystallization temperature of WY67 is about 1400 °C. Herein, the recovery kinetics, recrystallization kinetics, and the evolution of microstructure and texture of WY67 during isothermal annealing at temperatures ranging from 1300 ℃ to 1450 ℃ were investigated in detail. The effect of both the heterogeneity of the deformed microstructure and the yttria particles on the recovery and recrystallization was further studied. The results show that the stored energy of the deformed grains of yttria dispersion strengthened tungsten is texture-dependent and the grain with γ-fiber (normal direction // <111>) texture has the largest stored energy of 546 KJ/m3. The grains with higher stored energy are conducive to recrystallized nucleus/grain growth rather than nucleation during subsequent annealing. The recrystallized texture inherits the deformed texture and is mainly composed of γ-fiber texture. There are more pre-existing potential recrystallization nuclei in the elongated grains with larger deformation in the as-rolled microstructure. Micron-sized yttria particles can stimulate the formation of recrystallization nuclei through particle-stimulated nucleation mechanism, nevertheless, this is not the dominant nucleation mode for WY67 during recrystallization in this study. Fine (submicron) yttria particles hinder the recovery and recrystallization processes through the Smith–Zener pinning effect. [ABSTRACT FROM AUTHOR]

Simultaneous removal of antibiotics and heavy metals from the wastewater is still a sophisticated task with great challenge. Interestingly, •O 2 - as a long-lived and highly active specie can simultaneously remove antibiotics and heavy metals. Herein, we design a S-type heterojunction photocatalyst, which can efficiently generate •O 2 -. Characterizations and DFT calculation demonstrate that internal electric field provides powerful propulsion for migration of photo generated carriers between Zn 0.78 Cd 0.22 S and g-C 3 N 4 , effectively extends electronic life, thereby enhances the production of •O 2 -. Photocatalytic reaction rate constants under optimal composite ratio conditions were 3.1-times (ciprofloxacin) and 5.9-times (Cr (VI)) higher than Zn 0.78 Cd 0.22 S under the coexisting pollutant system. Benefiting from the inbuilt electric field to stimulate electron transfer and utilization as well as the dual function of •O 2 -, it reveals the possibility of practical wastewater treatment in the internal circulating fluidized bed reactor. [Display omitted] • A novel S-type heterojunction catalyst consisting of Zn 0.78 Cd 0.22 S and g-C 3 N 4. • The catalyst shows excellent photocatalytic activity on removal of CIP and Cr (VI). • Zn 0.78 Cd 0.22 S/g-C 3 N 4 can generate •O 2 - efficiently. • Built-in electric field effectively extends electronic life. [ABSTRACT FROM AUTHOR]

The efficient capture of radioactive iodine and sensitive detection of picric acid are very important to environmental protection. Herein, we synthesized two new flexible 4,4′-thiodianiline (TDA)-based covalent organic frameworks (TTDA and HTDA) by using simple Schiff-base polycondensation reactions with flexible 4,4′-thiodianiline (TDA) and 2,4,6-tris(4-formylphenoxy)-1,3,5-triazine (TPT − 3 − CHO) and hexa(4-formyl-phenoxy)cyclotriphosphazene (NOP − 6 − CHO). The flexible TDA-based COFs are porous, crystalline, and show high thermal stability and good chemical stability. Due to the high content of heteroatoms, abundant aromatic rings, and orderly network, it is conducive to electron transfer, the as-prepared flexible TDA-based COFs show outstanding dual properties of iodine adsorption and fluorescence sensing. The maximum iodine capacities of TTDA and HTDA are as high as 3.34 and 4.38 g g−1, respectively. The flexible TDA-based COFs can be used for sensing picric acid with low limits of detection (LODs) of 1.25 × 10−9 and 1.67 × 10−9 mol L−1 and high quenching constants (K SV) of 6.00 × 104 and 4.88 × 104 L mol−1, respectively. • Two new flexible TDA-based COFs with dual functions of iodine adsorption and fluorescence sensing PA were synthesized by Schiff base reaction. [ABSTRACT FROM AUTHOR]

Magnesium ions (Mg2+) are essential for the folding, functional expression, and structural stability of RNA molecules. However, predicting Mg2+–binding sites in RNA molecules based solely on RNA structures is still challenging. The molecular surface, characterized by a continuous shape with geometric and chemical properties, is important for RNA modelling and carries essential information for understanding the interactions between RNAs and Mg2+ ions. Here, we propose an approach named RNA–magnesium ion surface interaction fingerprinting (RMSIF), a geometric deep learning-based conceptual framework to predict magnesium ion binding sites in RNA structures. To evaluate the performance of RMSIF, we systematically enumerated decoy Mg2+ ions across a full-space grid within the range of 2 to 10 Å from the RNA molecule and made predictions accordingly. Visualization techniques were used to validate the prediction results and calculate success rates. Comparative assessments against state-of-the-art methods like MetalionRNA, MgNet, and Metal3DRNA revealed that RMSIF achieved superior success rates and accuracy in predicting Mg2+-binding sites. Additionally, in terms of the spatial distribution of Mg2+ ions within the RNA structures, a majority were situated in the deep grooves, while a minority occupied the shallow grooves. Collectively, the conceptual framework developed in this study holds promise for advancing insights into drug design, RNA co-transcriptional folding, and structure prediction. [ABSTRACT FROM AUTHOR]