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Hibernation, a survival strategy in mammals for extreme climates, induces physiological phenomena such as ischemia–reperfusion and metabolic shifts that hold great potential for advancements in modern medicine. Despite this, the molecular mechanisms underpinning hibernation remain largely unclear. This study used RNA‐seq and Iso‐seq techniques to investigate the changes in liver transcriptome expression of Rhinolophus pusillus during hibernation and active periods, as well as under different microhabitat temperatures. We identified 11 457 differentially expressed genes during hibernation and active periods, of which 395 showed significant differential expression. Genes associated with fatty acid catabolism were significantly upregulated during hibernation, whereas genes related to carbohydrate metabolism and glycogen synthesis were downregulated. Conversely, immune‐related genes displayed differential expression patterns: genes tied to innate immunity were significantly upregulated, while those linked to adaptive immunity and inflammatory response were downregulated. The analysis of transcriptomic data obtained from different microhabitat temperatures revealed that R. pusillus exhibited an upregulation of genes associated with lipid metabolism in lower microhabitat temperature. This upregulation facilitated an enhanced utilization rate of triglyceride, ultimately resulting in increased energy provision for the organism. Additionally, R. pusillus upregulated gluconeogenesis‐related genes regardless of the microhabitat temperature, demonstrating the importance of maintaining blood glucose levels during hibernation. Our transcriptomic data reveal that these changes in liver gene expression optimize energy allocation during hibernation, suggesting that liver tissue adaptively responds to the inherent stress of its function during hibernation. This study sheds light on the role of differential gene expression in promoting more efficient energy allocation during hibernation. It contributes to our understanding of how liver tissue adapts to the stressors associated with this state. [ABSTRACT FROM AUTHOR]

• Develop an electromechanical model to couple vehicle-track and traction drive systems. • Wheel polygon wear evolution analysis is performed including effects of interharmonic. • The pulsating torque with specific interharmonic excites the wheelset resonance at 70 km/h. The formation and development of wheel polygon wear (WPW) present significant challenges to the safety of railway vehicle operations. It is widely accepted that WPW occurs due to the mechanical vibration within the wheel-rail system. The output torque produced by the traction motor acts as the primary power source for the vehicle's movement. The pulsating torque, resulting from interharmonics can directly impact the wheelset's dynamic behavior, contributing to the occurrence of WPW. However, the precise mechanism by which interharmonics affect WPW remains incompletely understood. Therefore, this paper aims to establish the link between interharmonics originating from the electric traction drive system and the wheelset vibration. A comprehensive WPW evolution model that incorporates an electromechanical coupling model and a wheel wear calculation model is developed. This model allows to elucidate the intricate mechanism by which interharmonics impact WPW. The analysis indicates that when the locomotive is running at 70 km/h, the pulsating torque generated by the | 5 f − 7 f 0 | interharmonic can excite the 1st-order bending mode of the wheelset. This excitation triggers wheelset resonance, which ultimately leads to the development of 20th-order WPW. [ABSTRACT FROM AUTHOR]