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Introduced by the United Nations, Sustainable Development Goals (SDGs) aim at facilitating inclusive sustainable development. Responsiveness to SDGs is considered a key to addressing pressing development problems. The current literature focuses on the responsiveness of varied public organizations to SDGs, whereas SDGs' responsiveness of policy innovation labs (PILs) is understudied. Aiming to address both persistent and emerging social and environmental problems, PILs are aligned with SDGs. On the other hand, PILs seek innovative ways to generate policy solutions in collaboration with citizens through experimental methods and thus are more committed to the local public rather than international organizations. This paper investigates to what extent and in what way PILs respond to SDGs during policy formulation processes, both implicitly and explicitly. Data draws on a database the authors developed, identifying 211 European PILs. Thematic coding of PILs' websites reveals that 62.1% of the PILs implicitly promote at least one SDG. Additionally, sustainable cities and communities (SDG11) and good health and well-being (SDG3) are the two SDGs with the highest implicit-response rates, respectively. We apply grounded theory analysis from semi-structured interviews with senior PIL employees of 31 PILs to gauge their explicit views of SDGs. This inductive approach reveals three dimensions to SDGs: levels of responsiveness, different practices, and considerations that guide PILs on whether to comply with SDGs. A better understanding of PILs' response to SDGs provides a more nuanced portrayal of PILs as organizations aiming to craft innovative policy solutions that align with international frameworks. [ABSTRACT FROM AUTHOR]