15 results on '"Wiggins, Lisa"'
Search Results
2. Neurodevelopmental assessment of normocephalic children born to Zika virus exposed and unexposed pregnant people
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Alger, Jackeline, Cafferata, María Luisa, López, Raquel, Wiggins, Lisa D., Callejas, Allison, Castillo, Mario, Fúnes, Jenny, Rico, Fátima, Valencia, Diana, Varela, Douglas, Alvarez, Zulma, Berrueta, Mabel, Bock, Harry, Bustillo, Carolina, Calderón, Alejandra, Ciganda, Alvaro, García-Aguilar, Jorge, García, Kimberly, Gibbons, Luz, Gilboa, Suzanne M., Harville, Emily W., Hernández, Gustavo, López, Wendy, Lorenzana, Ivette, Luque, Marco T., Maldonado, Carlos, Moore, Cynthia, Ochoa, Carlos, Parham, Leda, Pastrana, Karla, Paternina-Caicedo, Angel, Rodríguez, Heriberto, Stella, Candela, Tannis, Ayzsa F., Wesson, Dawn M., Zúniga, Concepción, Tong, Van T., and Buekens, Pierre
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- 2024
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3. Depressive symptoms and activity engagement in autistic adolescents and those with other developmental disabilities
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Wiggins, Lisa D., Daniels, Julie, Overwyk, Katie, Croen, Lisa, DiGuiseppi, Carolyn, Bradley, Chyrise, Powell, Patrick, Dichter, Gabriel, Moody, Eric, and Pazol, Karen
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- 2024
- Full Text
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4. Remote Delivery of Allied and Behavioral Healthcare During COVID-19 for Children With Developmental Disabilities
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Wiggins, Lisa D., Tian, Lin H., Tinker, Sarah C., Yeargin-Allsopp, Marshalyn, DiGuiseppi, Carolyn G., Nadler, Cy, Powell, Patrick S., Moody, Eric J., Durkin, Maureen S., Fallin, M. Danielle, Ryerson, A. Blythe, Thierry, JoAnn M., Robinson, Britney, and Pazol, Karen
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- 2024
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5. COVID-19 Pandemic Impacts on Behavioral and Emotional Health of Young Children With Autism
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Pokoski, Olivia M., Crain, Hayley M., Furnier, Sarah M., Gangnon, Ronald E., Nadler, Cy, Moody, Eric J., Pazol, Karen, Stanley, Maria A., Wiggins, Lisa D., and Durkin, Maureen S.
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- 2024
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6. Racial and ethnic disparities in the co‐occurrence of intellectual disability and autism: Impact of incorporating measures of adaptive functioning
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Furnier, Sarah M., primary, Gangnon, Ronald, additional, Daniels, Julie L., additional, Ellis Weismer, Susan, additional, Nadler, Cy, additional, Pazol, Karen, additional, Reyes, Nuri M., additional, Rosenberg, Steven, additional, Rubenstein, Eric, additional, Wiggins, Lisa D., additional, Yeargin‐Allsopp, Marshalyn, additional, and Durkin, Maureen S., additional
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- 2024
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7. Economic impacts of the COVID-19 pandemic on families of children with autism and other developmental disabilities
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Pokoski, Olivia M., primary, Crain, Hayley, additional, DiGuiseppi, Carolyn, additional, Furnier, Sarah M., additional, Moody, Eric J., additional, Nadler, Cy, additional, Pazol, Karen, additional, Sanders, Jessica, additional, Wiggins, Lisa D., additional, and Durkin, Maureen S., additional
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- 2024
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8. Provider reported implementation barriers to hepatitis C elimination in Washington State.
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Cox-North, Paula, Wiggins, Lisa, Stockton, Jon, Huriaux, Emalie, Fliss, Mary, Evaskus, Leta, Pike, Kenneth, Basu, Anirban, and Kohler, Pamela
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HEPATITIS C prevention , *HEPATITIS C treatment , *HEALTH services accessibility , *CROSS-sectional method , *SELF-evaluation , *HUMAN services programs , *RESEARCH funding , *DISEASE eradication , *FISHER exact test , *CHI-squared test , *DESCRIPTIVE statistics , *MEDICAL screening , *COMPARATIVE studies , *DATA analysis software , *SOCIAL stigma , *LABOR supply - Abstract
Background: Despite curative treatment options since 2014, only 12% of individuals in Washington State diagnosed with Hepatitis C (HCV) received treatment in 2018. Washington State agencies launched an elimination plan in 2019 to promote access to and delivery of HCV screening and treatment. The purpose of this study is to evaluate provider and health system barriers to successful implementation of HCV screening and treatment across Washington State. Methods: This is a cross-sectional online survey of 547 physicians, nurse practitioners, physician assistants, and clinical pharmacists who provide care to adult patients in Washington State conducted in 2022. Providers were eligible if they worked in a primary care, infectious disease, gastroenterology, or community health settings. Questions assessed HCV screening and treating practices, implementation barriers, provider knowledge, observed stigma, and willingness to co-manage HCV and substance use disorder. Chi-squared or fishers exact tests compared characteristics of those who did and did not screen or treat. Results: Provider adoption of screening for HCV was high across the state (96%), with minimal barriers identified. Fewer providers reported treating HCV themselves (28%); most (71%) referred their patients to another provider. Barriers identified by those not treating HCV included knowledge deficit (64%) and lack of organizational support (24%). The barrier most identified in those treating HCV was a lack of treating clinicians (18%). There were few (< 10%) reports of observed stigma in settings of HCV treatment. Most clinicians (95%) were willing to prescribe medication for substance use disorders to those that were using drugs including alcohol. Conclusion: Despite widespread screening efforts, there remain barriers to implementing HCV treatment in Washington State. Lack of treating clinicians and clinician knowledge deficit were the most frequently identified barriers to treating HCV. To achieve elimination of HCV by 2030, there is a need to grow and educate the clinician workforce treating HCV. [ABSTRACT FROM AUTHOR]
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- 2024
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9. Using adaptive behavior scores to convey level of functioning in children with autism spectrum disorder: Evidence from the Study to Explore Early Development.
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Furnier, Sarah M, Ellis Weismer, Susan, Rubenstein, Eric, Gangnon, Ronald, Rosenberg, Steven, Nadler, Cy, Wiggins, Lisa D, and Durkin, Maureen S
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MOTOR ability ,COGNITIVE testing ,RESEARCH funding ,AUTISM ,FUNCTIONAL assessment ,PSYCHOLOGICAL adaptation ,SEVERITY of illness index ,DESCRIPTIVE statistics ,INTELLECTUAL disabilities ,CHILD development ,CHILD behavior ,SOCIALIZATION ,EVALUATION ,CHILDREN - Abstract
We examined relationships between measures of adaptive behavior, cognitive ability, and autism symptom severity in 1458 preschool-aged children with autism from the Study to Explore Early Development. While publications commonly describe autistic children as "low-" or "high-functioning" based on cognitive ability, relying solely on cognitive scores may obscure meaningful variation in functioning. We found significant heterogeneity in adaptive behavior scores of children with cognitive scores both above and below the threshold of two or more standard deviations below the population mean specified in the diagnostic criteria for intellectual disability (ID). Although cognitive and adaptive behavior scores were strongly associated in our sample, considerable variation in overall adaptive behavior and more than half in socialization and motor skills was unaccounted for by cognitive ability, autism symptom severity, and other covariates. Among children who could be designated "low-functioning" based on cognitive scores, 39.7% had composite adaptive behavior scores indicating no significant delays, while among those who might be designated "high-functioning," 9.0% had significant delays in overall adaptive behavior and 22.2% in socialization. These results suggest adaptive behavior scores capture variations in the autism phenotype not accounted for by other measures we considered. Autistic people are often described as "low-" or "high-functioning" based on their scores on cognitive tests. These terms are common in publications and in everyday communication. However, recent research and feedback from the autistic community suggests that relying on cognitive ability alone to describe functioning may miss meaningful differences in the abilities of autistic children and adults and in the kinds of support they may need. Additional methods are needed to describe "functioning" in autistic children. We examined whether scores from a test measuring adaptive behaviors would provide information on the functional abilities of children with autism that is different from cognitive ability and autism symptom severity. Adaptive behaviors include age-appropriate skills that allow people to function in their everyday lives and social interactions. We found that a large amount of the variation in adaptive behavior scores was not explained by cognitive development, autism symptom severity, and behavioral and emotional problems. In addition, there was a wide range of adaptive ability levels in children with autism in our study, including in those with low, average, or high cognitive scores. Our results suggest that adaptive behavior scores could provide useful information about the strengths and support needs of autistic children above and beyond measures of cognitive ability and autism symptom severity. Adaptive behavior scores provide important information on the needs of autistic people. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
10. Health and Education Services During the COVID-19 Pandemic Among Young Children with Autism Spectrum Disorder and Other Developmental Disabilities.
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Pazol, Karen, Tian, Lin H., DiGuiseppi, Carolyn, Durkin, Maureen S., Fallin, M. Daniele, Moody, Eric J., Nadler, Cy, Powell, Patrick S., Reyes, Nuri, Robinson, Britney, Ryerson, A. Blythe, Thierry, JoAnn M., Tinker, Sarah C., Wiggins, Lisa D., and Yeargin-Allsopp, Marshalyn
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- 2024
- Full Text
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11. Risk factors and clinical correlates of sensory dysfunction in preschool children with and without autism spectrum disorder.
- Author
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Wiggins, Lisa D., Overwyk, Katie, Daniels, Julie, Barger, Brian, Crain, Hayley, Grzadzinski, Rebecca, Moody, Eric, Reynolds, Ann, Reyes, Nuri, Rosenberg, Cordelia, Rosenberg, Steven, and Pazol, Karen
- Abstract
Sensory dysfunction is a common feature of autism spectrum disorder (ASD). The objectives of this analysis were to examine risk factors and clinical correlates of sensory dysfunction in preschool children with and without ASD. Children aged 2–5 years were enrolled in a multi‐site case–control study. Data were collected in eight areas across the United States in three phases. Caregivers completed an interview with questions on assisted delivery, maternal alcohol use, maternal anxiety during pregnancy, pregnancy weight gain, neonatal jaundice, preterm birth, and child sensory diagnosis given by a healthcare provider. Caregivers also completed an interview and questionnaires on sensory symptoms and clinical correlates of sensory dysfunction in their child. There were 2059 children classified as ASD, 3139 as other developmental delay or disability (DD), and 3249 as population comparison (POP). Caregivers reported significantly more sensory diagnoses and sensory symptoms in children classified as ASD than DD or POP (23.7%, 8.6%, and 0.8%, respectively, for a sensory diagnosis and up to 78.7% [ASD] vs. 49.6% [DD] for sensory symptoms). Maternal anxiety during pregnancy and neonatal jaundice were significantly associated with a sensory diagnosis and certain sensory symptoms in children with ASD and DD. Children's anxiety, attention deficits/hyperactivity, and sleep problems were significantly albeit subtly correlated with both a sensory diagnosis and sensory symptoms in children with ASD and DD. These findings support sensory dysfunction as a distinguishing symptom of ASD in preschool children and identify risk factors and clinical correlates to inform screening and treatment efforts in those with atypical development. Lay Summary: We found that sensory dysfunction was more common in children with autism than children without autism. Maternal anxiety during pregnancy and neonatal jaundice were related to children's sensory outcomes, as were and children's anxiety, attention deficits/hyperactivity, and sleep problems. Screening for sensory dysfunction in children with specific risk factors and clinical characteristics may help identify appropriate treatment strategies. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
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12. Child Age at Time of First Maternal Concern and Time to Services Among Children with Autism Spectrum Disorder.
- Author
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Van Dyke J, Rosenberg SA, Crume T, Reyes N, Alexander AA, Barger B, Fitzgerald R, Hightshoe K, Moody EJ, Pazol K, Rosenberg CR, Rubenstein E, Wiggins L, and DiGuiseppi C
- Abstract
Objective: Early treatment of autism spectrum disorder (ASD) can improve developmental outcomes. Children with ASD from minority families often receive services later. We explored factors related to child's age at time of mother's first concerns about child's development and subsequent time to service initiation among children with ASD., Methods: Analysis included 759 preschool-age children classified with ASD based on comprehensive evaluations. Factors associated with retrospectively reported child age at time of first maternal concern and subsequent time to service initiation were investigated using multiple linear regression and Cox proportional hazards., Results: Earlier maternal concern was associated with multiparity, ≥1 child chronic condition, externalizing behaviors, and younger gestational age, but not race/ethnicity. Time to service initiation was longer for children of non-Latino Black or other than Black or White race and higher developmental level and shorter for children with ≥1 chronic condition and older child age at first maternal concern., Conclusion: Parity, gestational age, and child health and behavior were associated with child age at first maternal concern. Knowledge of child development in multiparous mothers may allow them to recognize potential concerns earlier, suggesting that first time parents may benefit from enhanced education about normal development. Race/ethnicity was not associated with child's age when mothers recognized potential developmental problems; hence, it is unlikely that awareness of ASD symptoms causes racial/ethnic disparities in initiation of services. Delays in time to service initiation among children from racial/ethnic minority groups highlight the need to improve their access to services as soon as developmental concerns are recognized., Competing Interests: Disclosure: The authors declare no conflict of interest., (Copyright © 2024 Written work prepared by employees of the Federal Government as part of their official duties is, under the U.S. Copyright Act, a “work of the United States Government” for which copyright protection under Title 17 of the United States Code is not available. As such, copyright does not extend to the contributions of employees of the Federal Government.)
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- 2024
- Full Text
- View/download PDF
13. Using adaptive behavior scores to convey level of functioning in children with autism spectrum disorder: Evidence from the Study to Explore Early Development.
- Author
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Furnier SM, Ellis Weismer S, Rubenstein E, Gangnon R, Rosenberg S, Nadler C, Wiggins LD, and Durkin MS
- Subjects
- Humans, Male, Female, Child, Child, Preschool, Severity of Illness Index, Cognition, Adolescent, Child Development, Autism Spectrum Disorder psychology, Autism Spectrum Disorder physiopathology, Adaptation, Psychological
- Abstract
Lay Abstract: Autistic people are often described as "low-" or "high-functioning" based on their scores on cognitive tests. These terms are common in publications and in everyday communication. However, recent research and feedback from the autistic community suggests that relying on cognitive ability alone to describe functioning may miss meaningful differences in the abilities of autistic children and adults and in the kinds of support they may need. Additional methods are needed to describe "functioning" in autistic children. We examined whether scores from a test measuring adaptive behaviors would provide information on the functional abilities of children with autism that is different from cognitive ability and autism symptom severity. Adaptive behaviors include age-appropriate skills that allow people to function in their everyday lives and social interactions. We found that a large amount of the variation in adaptive behavior scores was not explained by cognitive development, autism symptom severity, and behavioral and emotional problems. In addition, there was a wide range of adaptive ability levels in children with autism in our study, including in those with low, average, or high cognitive scores. Our results suggest that adaptive behavior scores could provide useful information about the strengths and support needs of autistic children above and beyond measures of cognitive ability and autism symptom severity. Adaptive behavior scores provide important information on the needs of autistic people., Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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- 2024
- Full Text
- View/download PDF
14. The Human Phenotype Ontology in 2024: phenotypes around the world.
- Author
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Gargano MA, Matentzoglu N, Coleman B, Addo-Lartey EB, Anagnostopoulos AV, Anderton J, Avillach P, Bagley AM, Bakštein E, Balhoff JP, Baynam G, Bello SM, Berk M, Bertram H, Bishop S, Blau H, Bodenstein DF, Botas P, Boztug K, Čady J, Callahan TJ, Cameron R, Carbon SJ, Castellanos F, Caufield JH, Chan LE, Chute CG, Cruz-Rojo J, Dahan-Oliel N, Davids JR, de Dieuleveult M, de Souza V, de Vries BBA, de Vries E, DePaulo JR, Derfalvi B, Dhombres F, Diaz-Byrd C, Dingemans AJM, Donadille B, Duyzend M, Elfeky R, Essaid S, Fabrizzi C, Fico G, Firth HV, Freudenberg-Hua Y, Fullerton JM, Gabriel DL, Gilmour K, Giordano J, Goes FS, Moses RG, Green I, Griese M, Groza T, Gu W, Guthrie J, Gyori B, Hamosh A, Hanauer M, Hanušová K, He YO, Hegde H, Helbig I, Holasová K, Hoyt CT, Huang S, Hurwitz E, Jacobsen JOB, Jiang X, Joseph L, Keramatian K, King B, Knoflach K, Koolen DA, Kraus ML, Kroll C, Kusters M, Ladewig MS, Lagorce D, Lai MC, Lapunzina P, Laraway B, Lewis-Smith D, Li X, Lucano C, Majd M, Marazita ML, Martinez-Glez V, McHenry TH, McInnis MG, McMurry JA, Mihulová M, Millett CE, Mitchell PB, Moslerová V, Narutomi K, Nematollahi S, Nevado J, Nierenberg AA, Čajbiková NN, Nurnberger JI Jr, Ogishima S, Olson D, Ortiz A, Pachajoa H, Perez de Nanclares G, Peters A, Putman T, Rapp CK, Rath A, Reese J, Rekerle L, Roberts AM, Roy S, Sanders SJ, Schuetz C, Schulte EC, Schulze TG, Schwarz M, Scott K, Seelow D, Seitz B, Shen Y, Similuk MN, Simon ES, Singh B, Smedley D, Smith CL, Smolinsky JT, Sperry S, Stafford E, Stefancsik R, Steinhaus R, Strawbridge R, Sundaramurthi JC, Talapova P, Tenorio Castano JA, Tesner P, Thomas RH, Thurm A, Turnovec M, van Gijn ME, Vasilevsky NA, Vlčková M, Walden A, Wang K, Wapner R, Ware JS, Wiafe AA, Wiafe SA, Wiggins LD, Williams AE, Wu C, Wyrwoll MJ, Xiong H, Yalin N, Yamamoto Y, Yatham LN, Yocum AK, Young AH, Yüksel Z, Zandi PP, Zankl A, Zarante I, Zvolský M, Toro S, Carmody LC, Harris NL, Munoz-Torres MC, Danis D, Mungall CJ, Köhler S, Haendel MA, and Robinson PN
- Subjects
- Humans, Phenotype, Genomics, Algorithms, Rare Diseases, Biological Ontologies
- Abstract
The Human Phenotype Ontology (HPO) is a widely used resource that comprehensively organizes and defines the phenotypic features of human disease, enabling computational inference and supporting genomic and phenotypic analyses through semantic similarity and machine learning algorithms. The HPO has widespread applications in clinical diagnostics and translational research, including genomic diagnostics, gene-disease discovery, and cohort analytics. In recent years, groups around the world have developed translations of the HPO from English to other languages, and the HPO browser has been internationalized, allowing users to view HPO term labels and in many cases synonyms and definitions in ten languages in addition to English. Since our last report, a total of 2239 new HPO terms and 49235 new HPO annotations were developed, many in collaboration with external groups in the fields of psychiatry, arthrogryposis, immunology and cardiology. The Medical Action Ontology (MAxO) is a new effort to model treatments and other measures taken for clinical management. Finally, the HPO consortium is contributing to efforts to integrate the HPO and the GA4GH Phenopacket Schema into electronic health records (EHRs) with the goal of more standardized and computable integration of rare disease data in EHRs., (© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.)
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- 2024
- Full Text
- View/download PDF
15. Risk factors and clinical correlates of sensory dysfunction in preschool children with and without autism spectrum disorder.
- Author
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Wiggins LD, Overwyk K, Daniels J, Barger B, Crain H, Grzadzinski R, Moody E, Reynolds A, Reyes N, Rosenberg C, Rosenberg S, and Pazol K
- Subjects
- Female, Pregnancy, Child, Humans, Infant, Newborn, Child, Preschool, United States, Developmental Disabilities diagnosis, Case-Control Studies, Risk Factors, Autism Spectrum Disorder complications, Autism Spectrum Disorder epidemiology, Autism Spectrum Disorder diagnosis, Jaundice, Neonatal complications, Premature Birth
- Abstract
Sensory dysfunction is a common feature of autism spectrum disorder (ASD). The objectives of this analysis were to examine risk factors and clinical correlates of sensory dysfunction in preschool children with and without ASD. Children aged 2-5 years were enrolled in a multi-site case-control study. Data were collected in eight areas across the United States in three phases. Caregivers completed an interview with questions on assisted delivery, maternal alcohol use, maternal anxiety during pregnancy, pregnancy weight gain, neonatal jaundice, preterm birth, and child sensory diagnosis given by a healthcare provider. Caregivers also completed an interview and questionnaires on sensory symptoms and clinical correlates of sensory dysfunction in their child. There were 2059 children classified as ASD, 3139 as other developmental delay or disability (DD), and 3249 as population comparison (POP). Caregivers reported significantly more sensory diagnoses and sensory symptoms in children classified as ASD than DD or POP (23.7%, 8.6%, and 0.8%, respectively, for a sensory diagnosis and up to 78.7% [ASD] vs. 49.6% [DD] for sensory symptoms). Maternal anxiety during pregnancy and neonatal jaundice were significantly associated with a sensory diagnosis and certain sensory symptoms in children with ASD and DD. Children's anxiety, attention deficits/hyperactivity, and sleep problems were significantly albeit subtly correlated with both a sensory diagnosis and sensory symptoms in children with ASD and DD. These findings support sensory dysfunction as a distinguishing symptom of ASD in preschool children and identify risk factors and clinical correlates to inform screening and treatment efforts in those with atypical development., (© 2023 International Society for Autism Research and Wiley Periodicals LLC. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA.)
- Published
- 2024
- Full Text
- View/download PDF
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