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Anna Meiliana,1,2 Nurrani Mustika Dewi,2,3 Irma Rahayu Latarissa,1 Melisa Intan Barliana,3,4 Sofa Dewi Alfian,1,4 Trilis Yulianti,2 Andi Wijaya2 1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 2Prodia Clinical Laboratory, Jakarta, Indonesia; 3Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 4Center of Excellence for Pharmaceutical Care Innovation, Universitas Padjadjaran, Sumedang, IndonesiaCorrespondence: Anna Meiliana, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM. 21, Jatinangor, West Java, 45363, Indonesia, Email anna.meiliana@unpad.ac.idBackground: Sarcopenia is characterized by the progressive loss of skeletal muscle mass and poses a significant health challenge for older adults by increasing the risk of disability and decreasing quality of life. Yoga considers as a low-risk and beneficial exercise for older adults. This research aims to evaluate the potential of yoga practice as a preventive strategy against sarcopenia in Indonesian older adults.Methods: An observational cross-sectional research was conducted including 41 older adults aged 60– 87 years. The research focused on key biomarkers and functional assessments, including serum insulin-like growth factor 1 (IGF-1) levels, telomere length, gait speed, hand grip strength, and SARC-F questionnaire scores.Results: The results showed that participants aged 71– 80 years who practiced yoga for more than a year had significantly higher IGF-1 levels (p=0.04). While improvements in gait speed, hand grip strength, and SARC-F scores were observed, these changes were not statistically significant, and no significant differences were found in telomere length.Conclusion: Yoga in older adults was associated with higher IGF-1 levels and potential improvements in upper and lower extremity strength, though these findings were not statistically significant and did not influence telomere length. Yoga practice shows potential as an emerging adjuvant option but can not be applied as a single strategy for sarcopenia prevention in older adults.Keywords: aging, frailty, quality of life, yoga

A particular emphasis will be placed on the banner manufacturing service that Surya Printing Lampung offers to accomplish the purpose of this research, which is to investigate the influence of the promotion mix (7P) on the purchasing decision of consumers. A total of 96 samples, as part of this investigation, were used to perform multiple regression. The assistance of SPSS version 23 was used. According to the obtained regression analysis, factors such as value, position, location, and procedures, as well as physical evidence, have a favorable and significant impact through statistics on retail customers' purchasing decision. Off-product and people variables, on the other hand, do not provide evidence of such a link. While this is going on, the marketing mix (7P), which is determined by the F test, is affecting the decision to purchase banner manufacturing services from Surya Printing Lampung. Keywords: Purchasing Decision ;Marketing Mix (7P); Banner

This study evaluates the potential of utilizing tuna bone byproducts for acid-soluble collagen (ASC) extraction in Indonesia, targeting the biomedical industry’s growing collagen demand. Through the SuperPro Designer Simulator, the research assesses the economic feasibility of four varying input capacities (50, 100, 500, and 1000 kg). The simulation reveals that the most economical production process occurs with 1000 kg of raw materials, yielding a net present value (NPV) of $3,848,000, an internal rate of return (IRR) of 35.55%, and a payback period (PBP) of 2.16 years. The 1000-kg scenario emerged as the most economical input capacity due to its ability to adequately cover the substantial initial investment required. This outcome highlights the importance of scale efficiencies and operational optimizations in enhancing profitability, suggesting that large-scale operations are essential for justifying the significant capital expenditures involved. This project faces significant challenges in the limited availability of raw materials and the current extraction method’s efficiency, which could hinder the feasibility of scaling up production. This study identifies strategic solutions to these challenges by reducing investment through contract and shared manufacturing systems to lower upfront costs and improve the extraction process for higher efficiency and yield. These measures aim to address material scarcity and enhance production method efficacy, making the project more sustainable and economically viable. This study advocates further research and development to optimize the tuna bone byproduct extraction process as a solution to establish a competitive approach for collagen production within Indonesia’s biodiversity-rich maritime sector.

Background: The distinction between sharia and conventional practices has enabled sharia banks to withstand monetary crises. It is crucial to assess Sharia Commercial Banks' performance using capital adequacy ratios, operating expenses to income, net operating margin, and non-performing financing. These metrics help increase bank income through return on assets and address high financing issues, ensuring operational efficiency and alignment with management expectations. Purpose: This research aims to determine the factors that influence the performance of Sharia Commercial Banks which are proxied by return on assets as the dependent variable, capital adequacy ratio, operating expenses to operating income and net operating margin as the independent variable and non-performing financing as the intervening variable. Design/methodology/approach: This research is quantitative research using secondary data through financial reports. The total population from 2017 to 2023 is 16 banks. The analytical method used in this research is panel data regression with the help of the Eviews application through the Chow, Hausman and Lagrange tests. Finding/result: The research results show that the capital adequacy ratio has no effect on non-performing financing, operating expenses to operating income has no effect on non-performing financing, net operating margin has an effect on non-performing financing, the capital adequacy ratio has no effect on return on assets, operating expenses to operating income has an effect on return on assets and net operating margin has no effect on return on assets. Then the indirect influence is that non-performing financing is unable to mediate the influence of capital adequacy ratio on return on assets, non-performing financing is unable to mediate the influence of operating expenses to operating income on return on assets and non-performing financing is unable to mediate the influence of net operating margin on returns. Conclusion: The capital adequacy ratio, operating expenses to operating income and net operating margin have no influence on non-performing financing, then the capital adequacy ratio, net operating margin and non-performing financing have no influence on returns. on assets, while operating expenses to operating income have an influence on return on assets. An indirect influence can be conveyed that non-performing financing is unable to mediate the capital adequacy ratio, operating expenses to operating income, net operating margin to return on assets. This research can be used as a guide for assessing business performance through the factors that influence it. Originality/value (state of the art): In assessing the relationship between capital adequacy ratio, operating expenses to operating income and net operating margin to non-performing financing mediated by return on assets, this research explores the contributing factors to the prosperity of developing countries, especially Indonesia, which can help investors and policy makers in making decisions. appropriate way to improve company performance. Keywords: capital adequacy ratio, net operating margin, return on assets, non-performing financing, operating expenses on operating income

Consumption of protein by young children is known to support children’s growth and weight gain and thus may help prevent stunting. This study aimed to investigate variation in protein consumption between age groups, socioeconomic status (SES), and residential type among children aged 6-35 months in Indonesia. We analyzed data from the National Individual Food Consumption Survey (SKMI) 2014, which included 3,449 children. Our findings revealed that protein intake increased with children’s age in both urban and rural, ranging from 14.9 to 42.5 g/d in urban areas and 12.6 to 40.3 g/d in rural areas. In both urban and rural settings, protein intake increases significantly with better SES, from 33.4 to 37.8 g/d and 31.6 to 39.5 g/d, respectively. More younger children (6-11 months) had protein inadequacy than older age (73.9 vs 17.6% in urban and 82.8 vs 24.4% in rural areas). Conversely, older children from all SES had mean protein intake higher than the RDA. The primary protein sources were cereals (i.e. rice, plant protein), followed by offal, fish, and meat. This suggests that nutrition education along with improving protein consumption by younger children is crucial for growth and development as well as preventing stunting.

German cockroaches have been reported to have developed resistance to 42 active insecticide ingredients. An effort to minimize the development of resistance in German cockroaches is to use organic insecticides, one of which is a secondary metabolite from the entomopathogenic fungus Beauveria bassiana (B10). The purpose of this study was to determine the susceptibility of German cockroaches to the organic insecticide B10, which contains secondary metabolites of B. bassiana. This study used an experimental method with a completely randomized design consisting of ten treatments, namely concentrations of 0, 0.1, 0.5, 1, 5, 10, 20, 30, 40, and 50% (v / w). Each treatment unit used ten male German cockroaches which were repeated three times. Mortality data were analyzed using ANOVA followed by Duncan's test at a significance level of p

Poly(ethylene oxide) (PEO) with an oxygen group serves as a reactive site for the pathway of lithium‐ion transport. Reducing the PEO crystal domain in solid electrolytes is an extremely efficient approach for enhancing the mobility of ions. The present study applied various EO/Li molar ratios to modify the physical and electrochemical properties of PEO nanocomposite reinforced by nanocellulose. An elevated lithium salt concentration causes a gradual decline in crystallinity and mechanical strength. The electrochemical performance of the 13 EO/Li molar ratio voltammogram and charge–discharge shows efficient Li‐ion transport with 5.6 × 10−4 S/cm conductivity at room temperature and 131 mA h g−1 initial discharge capacity. The shifting glass transition and melting point at lower temperatures (−40.5 to −44.5°C and 45.3–43.8°C) suggest greater ion mobility throughout the large non‐crystalline structure. Lithium ions are limited by membrane weakening and re‐crystallization caused by high lithium salt (EM_11) concentrations. EM_13 has the highest specific capacity, operating voltage, and lithium transfer number depends on balanced electrochemical performance and physical features. XPS surface chemistry analysis explains LiF, Li2CO3, and Li2O solid electrolyte interfaces (SEI) in EM samples. A lower Li2O (11.62 at.%) than LiF (38.4 at.%) after cycling enhances Li‐ion diffusion and cell reversibility. [ABSTRACT FROM AUTHOR]

Lignin is a complex chemical heterogeneous polymer that forms a physical barrier to lignocellulose's biological and chemical hydrolysis, making lignocellulosic biomass challenging to degrade. Ligninolytic microorganisms play an essential role in lignin degradation by producing extracellular enzymes. Lignin peroxidase and manganese peroxidase are enzymes that play a role in lignin degradation. Forty-one bacterial isolates have been isolated from soil, kitchen waste, leaf litter, and cow dung. However, the ligninolytic activity of these isolates has yet to be discovered. This research aimed to determine the ligninolytic ability of bacteria isolated from soil, leaf litter, kitchen waste, and cow dung based on lignin peroxidase and manganese peroxidase activity. The study was conducted stages: isolate recultured, qualitative and quantitative testing of lignin peroxidase activity based on degradation of methylene blue dye, and qualitative and quantitative testing of manganese peroxidase activity based on degradation of phenol red dye. A total of four bacterial isolates from soil (Tn9, Tn14, Tn16, and Tn17) and two bacterial isolates from cow dung (KS2 and KS5) showed qualitative and quantitative lignin peroxidase activity. Manganese peroxidase activity was also shown by four isolates from soil (Tn2, Tn6, Tn14, and Tn16), one isolate from kitchen waste (SD1), and one isolate from cow dung (KS5) both qualitatively and quantitatively. The nine bacterial isolates that showed lignin peroxidase and manganese peroxidase activity have potential as lignin-degrading biological agents. [ABSTRACT FROM AUTHOR]

New Zealand's freshwater is under increasing pressure from intensified dairy farming. This study assesses agricultural nitrogen loads from small pastoral catchments contributing to eutrophication and periodic algae blooms in a lake. Using the Soil and Water Assessment Tool (SWAT+), we simulated hydrological processes and nutrient loads, incorporating water (δ2H, δ18O) and nitrate (δ15N, δ18O) isotope data to improve model performance. The SWAT+ model was calibrated and validated with flow and nitrate data, achieving R2 values of 0.65–0.90, Nash-Sutcliffe efficiency (NSE) of 0.46–0.82, and percent bias (PBIAS) between 10.24% and 33.48%. The study demonstrates that stable isotope insights can enhance SWAT+ modelling accuracy and highlight the need for better fertilizer management to reduce nutrient loads. [ABSTRACT FROM AUTHOR]

This study aims to analyze the influence of liquidity, earnings management, independent commissioners, and executive compensation of tax aggressiveness. The population in the study is a Banking Company Registered in Indonesia Stock Exchange in the period 2021-2022. The sample is taken by using purposive sampling method, where the banking company that issued the financial statements, did not move sector, listed its shares and did not have negative profit during the period 2021-2022. The design in the study is hypothesis testing, where the sample consists of 60 samples. Data processing using multiple linear regression with eviews 13.The results of this study found that liquidity, earnings management and independent komisais affect tax aggressiveness, while executive compensation does not affect the aggressiveness of taxes. Based on total adjusted R-Square results prove that liquidity, earnings management, independent commissionist, and executive compensation only affect 65.8%, while 24.2% is influenced by other variable not tested in this research. [ABSTRACT FROM AUTHOR]

Tetracycline contamination adversely affects aquatic ecosystems and increases the likelihood of antibiotic-resistant bacterium development, posing substantial risks to both environmental and human health. Consequently, there is a pressing need for efficient technologies to break down and eliminate tetracycline from water sources. This study aimed to synthesis a Fe3O4/Chi-PVA@NiO composite for photocatalytic degradation of tetracycline. Crosslinked chitosan (Chi) and polyvinyl alcohol (PVA) were applied to enhance the mechanical strength and increasing the physical and chemical stability of composites. XRD, UV-DRS, SEM-EDS, VSM, and FTIR were employed for characterization. The composite material exhibits magnetic characteristic, evidenced by a saturation magnetization of 67.13 emu/g and a band gap measuring 1.86 eV. The magnetic characteristics enhance the separation efficiency of the composite following the photocatalytic process with an external magnet and low band gap values, which enable degradation to occur under visible light radiation. The maximum degradation efficiency was attained at a pH of 5, a tetracycline concentration of 20 mg/L, a composite dosage of 0.5 g/L, and an irradiation time of 100 min with a degradation efficiency of 98.20%. The rate of degradation kinetics approximates a pseudo-first-order model in which the value of the degradation constant decreases as the concentration of tetracycline increases. The catalyst exhibited outstanding stability and reusability, achieving a high degradation efficiency of 94.10% over five consecutive cycles. The FTIR analysis revealed no notable alterations in the functional groups of the composite both prior and following the photocatalytic degradation process. This research offers an efficient and eco-friendly approach for removing tetracycline contaminants from the environment. [ABSTRACT FROM AUTHOR]

Objectives The World Health Organization has promoted the integration of smoking cessation programs into normal dental treatment since they have significant positive effects on oral health. However, there are stillmany barriers including a lack of knowledge about the smoking cessation counseling (SCC). The high incidence of smoking is an important health challenge in Indonesia. This study determined the relationships between sociodemographic factors and knowledge about the effects of smoking on oral health, as well as knowledge of, attitudes about, and barriers to SCC among clinical dental students in Indonesia. Materials and Methods This was a cross-sectional study utilizing a questionnaire involving clinical dental students throughout Indonesia. Clinical dental students from 32 dental schools in Indonesia were invited to participate in the study. Twenty-seven dental schools agreed to participate in the study and the estimated sample size was 416 participants. The questionnaire included sociodemographic data, smoking status, knowledge about the effects of smoking on oral health, and knowledge of, attitudes about, and barriers to SCC. Statistical Analysis Mann–Whitney U and Kruskal–Wallis tests were used to determine differences in knowledge about the effects of smoking on oral health and the knowledge of, attitudes about, and barriers to SCC among clinical dental students' sociodemographic factors and smoking status. The Spearman's correlation analysis was used to determine the correlation between knowledge of, attitudes about, and barriers to SCC. Results A total of 614 students participated in the study. Significant differences were found in students' knowledge regarding the effects of smoking based on smoking status, SCC based on educational stages, attitudes based on sex and smoking status, and barriers based on sex (p < 0.05). Significant relationships were found between students' knowledge of the effects of smoking and of SCC (r = 0.226), knowledge of the effects of smoking and attitudes about SCC (r = 0.110), knowledge of and attitudes about SCC (r = 0.162), knowledge of and barriers to SCC (r = –0.17), as well as attitudes about and barriers to SCC (i = –0.224). Conclusion Clinical dental students' knowledge regarding SCC are lacking, but they have positive attitude regarding SCC. It is necessary to improve education quality in every dental educational institution related to SCC. [ABSTRACT FROM AUTHOR]

Mathematical literacy is essential for tackling the issues of the 21st century. Creating educational videos that connect mathematical concepts to their practical use in daily life is important. This study has the following goals: 1) to create interactive video learning tools that enhance students' mathematical literacy; 2) to assess the suitability of these learning video tools according to input from both experts and students; and 3) to evaluate how effective the interactive learning videos are in boosting students' mathematical literacy skills. This study employs a research and development approach, utilizing a modified version of the ASSURE model, which involves only four of its six steps: 1) analyzing; 2) setting objectives; 3) choosing methods, media, and materials; and 4) using the media. The findings of the study include: 1) the creation of an interactive learning video aimed at enhancing students' mathematical literacy; 2) validation results from media specialists showed a score of 91.25%, categorized as very good; 3) validation results for the media content also scored 91.25%, falling under the very good category; and 4) there was a medium improvement in students' mathematical literacy skills, reflected by an N-Gain value of 0.61. Therefore, the interactive learning videos are effective tools for promoting students' mathematical literacy skills. [ABSTRACT FROM AUTHOR]