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Anna Meiliana,1,2 Nurrani Mustika Dewi,2,3 Irma Rahayu Latarissa,1 Melisa Intan Barliana,3,4 Sofa Dewi Alfian,1,4 Trilis Yulianti,2 Andi Wijaya2 1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 2Prodia Clinical Laboratory, Jakarta, Indonesia; 3Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 4Center of Excellence for Pharmaceutical Care Innovation, Universitas Padjadjaran, Sumedang, IndonesiaCorrespondence: Anna Meiliana, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM. 21, Jatinangor, West Java, 45363, Indonesia, Email anna.meiliana@unpad.ac.idBackground: Sarcopenia is characterized by the progressive loss of skeletal muscle mass and poses a significant health challenge for older adults by increasing the risk of disability and decreasing quality of life. Yoga considers as a low-risk and beneficial exercise for older adults. This research aims to evaluate the potential of yoga practice as a preventive strategy against sarcopenia in Indonesian older adults.Methods: An observational cross-sectional research was conducted including 41 older adults aged 60– 87 years. The research focused on key biomarkers and functional assessments, including serum insulin-like growth factor 1 (IGF-1) levels, telomere length, gait speed, hand grip strength, and SARC-F questionnaire scores.Results: The results showed that participants aged 71– 80 years who practiced yoga for more than a year had significantly higher IGF-1 levels (p=0.04). While improvements in gait speed, hand grip strength, and SARC-F scores were observed, these changes were not statistically significant, and no significant differences were found in telomere length.Conclusion: Yoga in older adults was associated with higher IGF-1 levels and potential improvements in upper and lower extremity strength, though these findings were not statistically significant and did not influence telomere length. Yoga practice shows potential as an emerging adjuvant option but can not be applied as a single strategy for sarcopenia prevention in older adults.Keywords: aging, frailty, quality of life, yoga

New Zealand's freshwater is under increasing pressure from intensified dairy farming. This study assesses agricultural nitrogen loads from small pastoral catchments contributing to eutrophication and periodic algae blooms in a lake. Using the Soil and Water Assessment Tool (SWAT+), we simulated hydrological processes and nutrient loads, incorporating water (δ2H, δ18O) and nitrate (δ15N, δ18O) isotope data to improve model performance. The SWAT+ model was calibrated and validated with flow and nitrate data, achieving R2 values of 0.65–0.90, Nash-Sutcliffe efficiency (NSE) of 0.46–0.82, and percent bias (PBIAS) between 10.24% and 33.48%. The study demonstrates that stable isotope insights can enhance SWAT+ modelling accuracy and highlight the need for better fertilizer management to reduce nutrient loads. [ABSTRACT FROM AUTHOR]

Objectives The World Health Organization has promoted the integration of smoking cessation programs into normal dental treatment since they have significant positive effects on oral health. However, there are stillmany barriers including a lack of knowledge about the smoking cessation counseling (SCC). The high incidence of smoking is an important health challenge in Indonesia. This study determined the relationships between sociodemographic factors and knowledge about the effects of smoking on oral health, as well as knowledge of, attitudes about, and barriers to SCC among clinical dental students in Indonesia. Materials and Methods This was a cross-sectional study utilizing a questionnaire involving clinical dental students throughout Indonesia. Clinical dental students from 32 dental schools in Indonesia were invited to participate in the study. Twenty-seven dental schools agreed to participate in the study and the estimated sample size was 416 participants. The questionnaire included sociodemographic data, smoking status, knowledge about the effects of smoking on oral health, and knowledge of, attitudes about, and barriers to SCC. Statistical Analysis Mann–Whitney U and Kruskal–Wallis tests were used to determine differences in knowledge about the effects of smoking on oral health and the knowledge of, attitudes about, and barriers to SCC among clinical dental students' sociodemographic factors and smoking status. The Spearman's correlation analysis was used to determine the correlation between knowledge of, attitudes about, and barriers to SCC. Results A total of 614 students participated in the study. Significant differences were found in students' knowledge regarding the effects of smoking based on smoking status, SCC based on educational stages, attitudes based on sex and smoking status, and barriers based on sex (p < 0.05). Significant relationships were found between students' knowledge of the effects of smoking and of SCC (r = 0.226), knowledge of the effects of smoking and attitudes about SCC (r = 0.110), knowledge of and attitudes about SCC (r = 0.162), knowledge of and barriers to SCC (r = –0.17), as well as attitudes about and barriers to SCC (i = –0.224). Conclusion Clinical dental students' knowledge regarding SCC are lacking, but they have positive attitude regarding SCC. It is necessary to improve education quality in every dental educational institution related to SCC. [ABSTRACT FROM AUTHOR]

Tetracycline contamination adversely affects aquatic ecosystems and increases the likelihood of antibiotic-resistant bacterium development, posing substantial risks to both environmental and human health. Consequently, there is a pressing need for efficient technologies to break down and eliminate tetracycline from water sources. This study aimed to synthesis a Fe3O4/Chi-PVA@NiO composite for photocatalytic degradation of tetracycline. Crosslinked chitosan (Chi) and polyvinyl alcohol (PVA) were applied to enhance the mechanical strength and increasing the physical and chemical stability of composites. XRD, UV-DRS, SEM-EDS, VSM, and FTIR were employed for characterization. The composite material exhibits magnetic characteristic, evidenced by a saturation magnetization of 67.13 emu/g and a band gap measuring 1.86 eV. The magnetic characteristics enhance the separation efficiency of the composite following the photocatalytic process with an external magnet and low band gap values, which enable degradation to occur under visible light radiation. The maximum degradation efficiency was attained at a pH of 5, a tetracycline concentration of 20 mg/L, a composite dosage of 0.5 g/L, and an irradiation time of 100 min with a degradation efficiency of 98.20%. The rate of degradation kinetics approximates a pseudo-first-order model in which the value of the degradation constant decreases as the concentration of tetracycline increases. The catalyst exhibited outstanding stability and reusability, achieving a high degradation efficiency of 94.10% over five consecutive cycles. The FTIR analysis revealed no notable alterations in the functional groups of the composite both prior and following the photocatalytic degradation process. This research offers an efficient and eco-friendly approach for removing tetracycline contaminants from the environment. [ABSTRACT FROM AUTHOR]